Early Indicators Of Noise Injury: Are Decreased Auditory Processing Skills Evident In Noise-exposed Adults Prior To Diagnosis Of Hearing Loss?
Funder
National Health and Medical Research Council
Funding Amount
$367,605.00
Summary
Recent research indicates that noise-exposed individuals with similar hearing thresholds to non-noise exposed counterparts are more likely to have diminished temporal and spectral auditory processing abilities. This research aims to determine the relationship between noise exposure levels and auditory processing difficulties; the influence of musical training in ameliorating these difficulties; and a neurological model of causation, operation and possible remediation of these difficulties.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775702
Funder
Australian Research Council
Funding Amount
$337,000.00
Summary
Climate controlled physical containment 2 (PC2) and pathogen/ insect contained glasshouse facility. The Australian economy relies heavily on agricultural production. The outcomes of the projects supported by these growth facilities will be of economic benefit to the nation by producing new knowledge of plant-insect and plant-pathogen interactions, how plants acquire essential nutrients, and how they respond to environmental stress. The research outcomes will benefit the environment by increasin ....Climate controlled physical containment 2 (PC2) and pathogen/ insect contained glasshouse facility. The Australian economy relies heavily on agricultural production. The outcomes of the projects supported by these growth facilities will be of economic benefit to the nation by producing new knowledge of plant-insect and plant-pathogen interactions, how plants acquire essential nutrients, and how they respond to environmental stress. The research outcomes will benefit the environment by increasing legume production and so reducing land degradation and risk of nitrate contamination of waterways and lowering the environmental risk from agrochemicals by developing safer strategies for control of pests and diseases. In addition, a number of projects that will benefit from the glasshouse facilities aim to produce healthier and safer foods.Read moreRead less
Predicting Language Skills From Early Auditory Speech Discrimination In Infants With Hearing Loss: Implications For Early Management And Intervention
Funder
National Health and Medical Research Council
Funding Amount
$706,113.00
Summary
Now that newborn hearing checks are available, hearing loss can be picked up soon after birth and hearing aids are fitted shortly after. Although procedures exist for checking that the devices make sounds audible, there is no way to evaluate their effectiveness for supporting a child’s auditory discrimination. This study aims to 1) develop new clinical tools for assessing infants’ auditory discrimination, and 2) determine whether early discrimination predicts spoken language at 3 years of age.
An investigation of respiration in stuttering. Australia leads the world in stuttering research, and this project will maintain that profile. The research aims to establish if breathing has a causal role in stuttering. The new knowledge produced will support or weaken current theories of the cause of stuttering and will contribute to understanding the nature of the disorder. In particular, it will be applied to develop more effective and efficient treatments for chronic stuttering.
Establishing the relationship between anxiety and stuttering. The present project will establish basic knowledge about the disorder of stuttering, which will contribute to offsetting the personal and community costs of the disorder by guiding empirical investigations into its nature and the development of future treatments. Further benefits at the population level will occur by provision to the public of basic information about the disorder assembled from this project. By conveying information f ....Establishing the relationship between anxiety and stuttering. The present project will establish basic knowledge about the disorder of stuttering, which will contribute to offsetting the personal and community costs of the disorder by guiding empirical investigations into its nature and the development of future treatments. Further benefits at the population level will occur by provision to the public of basic information about the disorder assembled from this project. By conveying information from the present project to clinicians who treat stuttering patients, the project will benefit Australians who stutter.Read moreRead less
New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput anal ....New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput analytical cultivation, molecular networking, and chemical and biological analyses, expected outcomes include an enhanced ability to explore and exploit valuable chemistry hidden within microbial genomes, leading to the discovery of new classes of natural antiparasitic to safeguard livestock.
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Studies Of The Effects Of Asymmetric Hearing Loss On The Brain
Funder
National Health and Medical Research Council
Funding Amount
$920,076.00
Summary
Hearing loss impairs the normal development and maintenance of auditory pathways. Irreversible pathologies persist when hearing is not restored in a timely manner. While cochlear implantation is the accepted treatment for profound sensorineural hearing loss, there is significant variability in outcomes. Some of this variability is linked to the degree of hearing asymmetry. Thus, we propose to study brain changes in the auditory system that accompany asymmetric hearing impairment.
The Role Of Nuclear Architecture In The DNA Damage Response
Funder
National Health and Medical Research Council
Funding Amount
$561,966.00
Summary
The goal of the proposed research is to understand how dynamic changes to the chromatin genome packaging network, interact with the DNA damage response and gene expression machinery, to repair damaged DNA and the impact this has on cancer biology. To do so we are combining cutting edge molecular biology techniques with innovative novel microscopy methods developed by our research team, that far exceed the spatiotemporal resolution currently used to study chromatin biology.
Chemicals in compostable food contact paper packaging materials. The aim of this project is to understand the presence of persistent chemicals in recyclable and compostable food contact materials (FCMs). These types of products are destined for recycling or biowaste streams that bridge the gap from take-make-dispose and into a circular economy. Currently, the knowledge of the chemicals in these products is limited but we need to ensure that they are safe and do not unnecessarily contaminate reso ....Chemicals in compostable food contact paper packaging materials. The aim of this project is to understand the presence of persistent chemicals in recyclable and compostable food contact materials (FCMs). These types of products are destined for recycling or biowaste streams that bridge the gap from take-make-dispose and into a circular economy. Currently, the knowledge of the chemicals in these products is limited but we need to ensure that they are safe and do not unnecessarily contaminate resource recovery streams. It is expected that this project will develop a framework that could be used by industry and government to prevent chemicals of concern persisting in a circular economy, providing environmental and economic benefits through reduced risk of chemical exposure and unnecessary remediation costs.Read moreRead less