Interfacial interactions with hydrogel biomaterials. The interactions between cells of the body and the surfaces of medical implants are controlled largely by the molecules that are adsorbed on the surface. The aim of this project is to evaluate the effect of modifying hydrogel biomaterials on the interactions of the molecules with the hydrogel. This, in turn, allows us to determine the factors affecting the control of the cell's response. The significance of this work is in the improved ability ....Interfacial interactions with hydrogel biomaterials. The interactions between cells of the body and the surfaces of medical implants are controlled largely by the molecules that are adsorbed on the surface. The aim of this project is to evaluate the effect of modifying hydrogel biomaterials on the interactions of the molecules with the hydrogel. This, in turn, allows us to determine the factors affecting the control of the cell's response. The significance of this work is in the improved ability to control cellular responses to implants. Such improved response will result in better health outcomes for patients, and outcomes in the form of papers and intellectual property.
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Male germ line transgenesis and siRNA technology for manipulating genes in domestic species. Professor Shemesh has successfully developed male germ line transgenesis in species such as bovine and chicken. This technology allows genes to be manipulated via sperm in a wide range of animals besides mice, avoiding the need for a female in vitro fertilization regimen. He is curently applying interference RNA (siRNA) transgenically to manipulate genes in vivo. Together these two technologies offer imm ....Male germ line transgenesis and siRNA technology for manipulating genes in domestic species. Professor Shemesh has successfully developed male germ line transgenesis in species such as bovine and chicken. This technology allows genes to be manipulated via sperm in a wide range of animals besides mice, avoiding the need for a female in vitro fertilization regimen. He is curently applying interference RNA (siRNA) transgenically to manipulate genes in vivo. Together these two technologies offer immense possibilities to manipulate a wide range of species for economic, biotechnological or medical research purposes. Professor Shemesh wishes to come to Adelaide to establish these technologies there as parts of ongoing research projects, related to the physiology of the ovarian hormone relaxin in aging research.Read moreRead less
A comparative study on women's policy machinery in Korea and Australia. This project aims to contribute to the better understanding of women's policy machinery in Korea and Australia in order to develop more effective policymaking and implementation. This topic is theoretically and empirically under researched. The project, as a major comparative study on women's policies in two countries will make a significant contribution to the understanding of women's policy making process in a specific nat ....A comparative study on women's policy machinery in Korea and Australia. This project aims to contribute to the better understanding of women's policy machinery in Korea and Australia in order to develop more effective policymaking and implementation. This topic is theoretically and empirically under researched. The project, as a major comparative study on women's policies in two countries will make a significant contribution to the understanding of women's policy making process in a specific national context. This research will investigate the relevance of national machineries for the advancement of women. Appropriate mechanisms through which the mainstreaming of gender can take place are considered, and the levels of governance involved - the relationship between gender mainstreaming and state structures, and the effect of this relationship on policy implementation will be examined. Thus, this research will contribute to the better understanding of how and by what processes women's interests are represented to the state policy making structures.Read moreRead less
Combining the soft with the hard: The assembly of artificial cell membranes on porous semiconductors. The platform technologies developed in this project will have a wide range of applications. They will reveal new insights into drug-membrane and drug-protein interactions underpinning development of a new generation of drugs acting on transmembrane proteins that are linked to a wide range of diseases. The development of membrane-based biosensing devices targeting ion channels, membrane active pe ....Combining the soft with the hard: The assembly of artificial cell membranes on porous semiconductors. The platform technologies developed in this project will have a wide range of applications. They will reveal new insights into drug-membrane and drug-protein interactions underpinning development of a new generation of drugs acting on transmembrane proteins that are linked to a wide range of diseases. The development of membrane-based biosensing devices targeting ion channels, membrane active peptides or toxins which can be applied to biomedical diagnostics, biotoxin detection, environmental and food control will be readily achievable. This international interdisciplinary nanobiotechnology programme and its outcomes will enhance Australia's abilities in frontier technologies and build research strength in nanobiotechnology.Read moreRead less