Design and verification of correct, efficient and secure concurrent systems. This project aims to provide methods for the design and verification of correct, secure and efficient concurrent software that are scalable and mechanised. Computers with multiple processors are now the norm and are used in a wide range of safety, security and mission critical software applications such as transport, health and infrastructure. These multi-core architectures have the potential to lead to important effici ....Design and verification of correct, efficient and secure concurrent systems. This project aims to provide methods for the design and verification of correct, secure and efficient concurrent software that are scalable and mechanised. Computers with multiple processors are now the norm and are used in a wide range of safety, security and mission critical software applications such as transport, health and infrastructure. These multi-core architectures have the potential to lead to important efficiency gains, but can introduce complex and error-prone behaviours that cannot be managed using traditional software development approaches. This project will produce better, scalable and mechanised methods for the design and verification of such software which is expected to reduce the prevalence of failures in efficient, modern software.Read moreRead less
Environmental Influences In The Establishment Of The Epigenetic Landscape In Children
Funder
National Health and Medical Research Council
Funding Amount
$695,097.00
Summary
The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells ....The DNA in each of our cells does not exist alone, it is packaged into complex structures called chromosomes, through association with many different proteins. The distribution of these proteins varies along the length of a chromosome depending on the type of cell and this phenomenon is called 'epigenetics', literally meaning 'above the DNA'. Epigenetic analysis is the study of how proteins and other molecules can change the activity of a gene without changing the DNA sequence. All of our cells use epigenetic changes to help control how they grow and develop. Evidence suggests a direct link between diet and environmental influences on our epigenetic profile. Recent research has traced the origins of many of the health problems of adult life back to the earliest periods of development _ to the time spent in the womb and the first few years of life. If we are born with a low birth weight, we are more likely to get sick later in life. Overwhelming evidence exists that the environment in the womb is critical for a healthy birth weight (and health in later life) and it is thought that epigenetics may be the missing link between this environment, low birth weight, and therefore health in later life. In addition, mounting evidence supports a general link between epigenetic de-regulation and predisposition to disease. However, the timing and the overall contribution of environmental- genetic influences to the establishment of faulty epigenetic markings remain largely unknown. Twins are the best model to study this link as they share similar (but not identical environments) and some share identical genetic makeup. Using twins, Dr Jeffrey Craig and his team will investigate the factors in the prenatal environment that modify specific cells, leading to low birth weight and increase disease risk later in life. They predict that this occurs via specific changes in gene activity caused by epigenetic disruption.Read moreRead less
Early Nutrition, Epigenetics And Developmental Outcomes In Children.
Funder
National Health and Medical Research Council
Funding Amount
$550,093.00
Summary
Increasing evidence demonstrates that early nutrition, including in pregnancy, has long lasting programming effects on later health of children. Evidence implicates epigenetics (literally ‘above DNA’) in mediating these effects. The most convincing data exists for obesity and related disorders such as metabolic syndrome, diabetes, and heart disease. The focus of this project is on understanding how ‘epigenetic’ mechanisms are influencing the way our genes function to cause these disorders.
Middle Classes, New Media and Indie Networks in Post Authoritarian Indonesia. The study shall deepen Australians' appreciation of a little-known but strategically-placed facet of Indonesian society. It shall enhance understanding of the opinions, worldviews and cultural productions of young Indonesians, and of the culturally specific character of their digital engagements. In its focus on urban middle class Indonesians, the project shall produce new and detailed knowledge about the cultures and ....Middle Classes, New Media and Indie Networks in Post Authoritarian Indonesia. The study shall deepen Australians' appreciation of a little-known but strategically-placed facet of Indonesian society. It shall enhance understanding of the opinions, worldviews and cultural productions of young Indonesians, and of the culturally specific character of their digital engagements. In its focus on urban middle class Indonesians, the project shall produce new and detailed knowledge about the cultures and lifestyles of one of Australia's most important higher education markets, and its role in the society. Finally, the project shall deepen the Australian public's understandings of Indonesia as an increasingly complex, disjunctive society.Read moreRead less
Pop Cultures in Indonesia: a New Asian Politics of Pleasure and Identity. The study addresses one of National Research Priorities (Goal 4 'Safeguarding Australia'), by better 'understanding our region and the world', and boosting Australia's 'soft power'. Recent changes in Indonesia render much of our knowledge about that society outdated. The study will deliver a significant contribution to the urgent revitalisation of Indonesian and cultural studies. It will hopefully elevate the quality of ou ....Pop Cultures in Indonesia: a New Asian Politics of Pleasure and Identity. The study addresses one of National Research Priorities (Goal 4 'Safeguarding Australia'), by better 'understanding our region and the world', and boosting Australia's 'soft power'. Recent changes in Indonesia render much of our knowledge about that society outdated. The study will deliver a significant contribution to the urgent revitalisation of Indonesian and cultural studies. It will hopefully elevate the quality of our public debate about the world's largest Muslim populated country and Australia's neighbour, by paying serious and overdue attention to the brightest sides of contemporary Indonesia that have occupied the minds of one hundred millions or so ordinary people there.Read moreRead less
Defining Genetic And Epigenetic Variation During Early Development
Funder
National Health and Medical Research Council
Funding Amount
$996,075.00
Summary
We all began life with a set of genes inherited from our parents. However, it's now known that from the time we were in the womb onwards that genes can be turned off and on by the environment or even completely lost or gained. Even what your mother ate or how she behaved while she was pregnant could have influenced your future health. Because people are so different, we are studying the subtle differences between twins to tease out the factors that may influence our genes and our health.
Mobile Indonesians: social differentiation and digital literacies in the twenty first century. This is the first dedicated study of the social implications of mobile telephony's recent and rapid popularisation throughout the country. This project will study metropolitan, urban and rural users to understand how mobile phones create the new and unexpected social networks which will shape tomorrow's Indonesians.
Western Desert speech styles and verbal arts. Verbal arts are central to social interaction. In the Western Desert Ngaanyatjarra and Ngaatjatjarra people use special speech styles to mark particular occasions and life transitions. Led by Ngaatjatjarra linguist, researcher and educator Elizabeth Marrkilyi Ellis, the research team aims to build on a corpus of these endangered oral traditions. Following in-depth linguistics analysis the project aims to implement strategies to revitalise these endan ....Western Desert speech styles and verbal arts. Verbal arts are central to social interaction. In the Western Desert Ngaanyatjarra and Ngaatjatjarra people use special speech styles to mark particular occasions and life transitions. Led by Ngaatjatjarra linguist, researcher and educator Elizabeth Marrkilyi Ellis, the research team aims to build on a corpus of these endangered oral traditions. Following in-depth linguistics analysis the project aims to implement strategies to revitalise these endangered styles through dynamic contemporary applications thus reintegrating them into the language socialisation framework of youth. The project aims to assist Aboriginal people to safeguard their heritage and contribute to a wider public appreciation of Aboriginal languages and cultures.Read moreRead less
Social cognition and language - the design resources of grammatical diversity. This project will (a) improve Australia's capacity to interact and communicate with other cultures (b) promote advanced training and research (including 9 doctoral students) on the languages of our region (c) carry out extensive new research on 20 languages of the Pacific region, most of which represent gravely endangered cultural traditions (d) draw on the design solutions identified in these languages to develop ....Social cognition and language - the design resources of grammatical diversity. This project will (a) improve Australia's capacity to interact and communicate with other cultures (b) promote advanced training and research (including 9 doctoral students) on the languages of our region (c) carry out extensive new research on 20 languages of the Pacific region, most of which represent gravely endangered cultural traditions (d) draw on the design solutions identified in these languages to develop models appropriate to the social cognition element of human-computer and computer-computer interfacesRead moreRead less
Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. ....Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. This project will generate new knowledge of how to encourage effective word-of-mouth for pro-social behaviours. Expected outcomes include producing culturally relevant, validated resources that will significantly benefit Australia by encouraging effective conversations to promote blood donation in all communities.Read moreRead less