Subject-specific computational models for accurate evaluation of muscle function in human locomotion. The purpose of this project is to advance current understanding of muscle function during human locomotion. The most significant outcome will be the development of novel computational tools that can play a pivotal role in the healthcare industry through the prevention, diagnosis and treatment of movement disorders.
Large-scale three dimensional deformation of the lithosphere by subduction and mantle flow. We will be modelling of the dynamics of the Earth's crust and shallow lithosphere in response to the huge stresses created by plate motions. For Australia these stresses are transmitted from the distant plate boundaries, but they have a direct controlling influence on the evolution of the petroleum rich basins of Australia. These basins have reached maturity; further exploration will be in deep water wher ....Large-scale three dimensional deformation of the lithosphere by subduction and mantle flow. We will be modelling of the dynamics of the Earth's crust and shallow lithosphere in response to the huge stresses created by plate motions. For Australia these stresses are transmitted from the distant plate boundaries, but they have a direct controlling influence on the evolution of the petroleum rich basins of Australia. These basins have reached maturity; further exploration will be in deep water where geophysical prospecting methods are unreliable. Model-driven "exploration geodynamics" methods such as those we are developing will be needed to support traditional exploration techniques in these areas.Read moreRead less
Three dimensional computational models of geological basin and hinterland evolution incorporating lithospheric mantle and surface processes. Petroleum exploration in deepwater areas offshore Australia is becoming increasingly important as more accessible, shallow water oil reserves near exhaustion. Geological simulation is an important tool for understanding deep water basins where geophysical imaging techniques are less effective. This project will develop 3D computational models relevant to un ....Three dimensional computational models of geological basin and hinterland evolution incorporating lithospheric mantle and surface processes. Petroleum exploration in deepwater areas offshore Australia is becoming increasingly important as more accessible, shallow water oil reserves near exhaustion. Geological simulation is an important tool for understanding deep water basins where geophysical imaging techniques are less effective. This project will develop 3D computational models relevant to understanding the development and evolution of geological basins and the sediments that fill them. The models will be integrated with available offshore data for potentially prospective Australian basins in the Northwest Shelf and the Southern Australian margin.Read moreRead less
Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also ....Co-design and dynamic mission optimisation of hypersonic flight vehicles. This project aims to deliver fundamental knowledge by integrating the modelling and control with the design of next generation hypersonic platforms. In an era where Australia's national security reliance on geographic isolation and support from allied forces are being challenged, the research outcomes of this project will play an important role in understanding the capabilities of hypersonic systems. The project will also have significant spillover benefits into other complex system domains, where computational tools can be used to aid in design leading to high embedded-IP products for Australian industry. Furthermore, the proposal encompasses a strong research training aspect, with graduates exposed to leading edge industry and academia.Read moreRead less
Reducing The Greatest Uncertainty In Radiotherapy.
Funder
National Health and Medical Research Council
Funding Amount
$594,197.00
Summary
The weakest link in radiotherapy is defining treatment volumes (contouring). Lack of accuracy and consistency in clinical trial contouring has been shown to result in reduced patient outcomes. Manual review of contouring is resource intensive, expensive and for advanced treatments unachievable in a timely fashion. We will assess an automated approach to contouring assessment using 4 clinical trial datasets, changing practice for future studies and enabling consistent assessment in the clinic.
Industrial Transformation Research Hubs - Grant ID: IH130200012
Funder
Australian Research Council
Funding Amount
$2,748,358.00
Summary
ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, ....ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, inaccessible remote and deep exploration targets. The Hub will fuse multidimensional data into five dimensional basin models (space and time, with uncertainty estimates) by coupling the evolution of mantle flow, crustal deformation, erosion and sedimentary processes, achieving a quantum leap in basin modelling and petroleum systems analysis.Read moreRead less
Thermo-mechanical interactive atlas of basin evolution. We propose to create a thermo-mechanical interactive atlas of basin evolution as a desktop geodynamic modelling resource for exploration geologists. The atlas will allow the user to iteratively run our 2D/3D basin modelling software ELLIPSIS to alter model parameters until they match observed basin geometries or thermal history. Model iteration will be based on interactive user evaluation of model outputs and genetic algorithms, which pr ....Thermo-mechanical interactive atlas of basin evolution. We propose to create a thermo-mechanical interactive atlas of basin evolution as a desktop geodynamic modelling resource for exploration geologists. The atlas will allow the user to iteratively run our 2D/3D basin modelling software ELLIPSIS to alter model parameters until they match observed basin geometries or thermal history. Model iteration will be based on interactive user evaluation of model outputs and genetic algorithms, which progressively modify the solution set by mimicking the evolutionary behavior of biological systems (selection, cross-over and mutation), until an acceptable result is achieved. The interactive atlas will be applied to Australian and international case studies.Read moreRead less
Special Research Initiatives - Grant ID: SR0354793
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a mul ....A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a multidisciplinary spectrum. This will drive an integrated and accelerated program of discovery and technological development, enhancing Australia's leadership in this crucial field and helping to highlight new biotechnology opportunities and capture social and economic benefits for the nation. Read moreRead less
Special Research Initiatives - Grant ID: SR0354575
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and me ....Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and metadata modelling between these traditionally separate research groups, with the outcome of improving research efficiency and lowering costs. EON-ITNET will form an alliance with the Caltech-based GeoFramework, which is advancing a novel object-oriented data analysis environment, binding community software for Earth visualisation and simulation to 4D data bases.Read moreRead less
The Initiation and 3D Evolution of Instabilities in the Deep Continental Lithosphere. This project is part of a new international initiative in the Geodynamics of the Australian Plate bringing together studies of the active tectonics of the boundary regions of our plate and the ancient analogues of these processes which are locked into the stable interior of the Australian continent. The proposed research is a good fit to the Identification and Extraction of Deep Earth Resources priority goal. D ....The Initiation and 3D Evolution of Instabilities in the Deep Continental Lithosphere. This project is part of a new international initiative in the Geodynamics of the Australian Plate bringing together studies of the active tectonics of the boundary regions of our plate and the ancient analogues of these processes which are locked into the stable interior of the Australian continent. The proposed research is a good fit to the Identification and Extraction of Deep Earth Resources priority goal. Detachment of the lithosphere is associated with fertile mantle being emplaced at shallow depth below the crust; an important precursory event for mineralization. The project builds upon AuScope (NCRIS 5.13) to create infrastructure for a new, smart resource exploration and extraction industry based on modelling and simulation.Read moreRead less