Development of a Cost-Effective Organic-Inorganic Nanocomposite for High Quality Gravure Printing. Gravure printing is the printing process of choice for long runs and high quality. The conventional process involves the manufacture of copper-plated, chrome-coated cylinders into which the desired image is engraved. The cylinders have high manufacturing and operating costs. The chemicals used in the process are highly toxic and therefore pose major threats to humans and environment. This proposa ....Development of a Cost-Effective Organic-Inorganic Nanocomposite for High Quality Gravure Printing. Gravure printing is the printing process of choice for long runs and high quality. The conventional process involves the manufacture of copper-plated, chrome-coated cylinders into which the desired image is engraved. The cylinders have high manufacturing and operating costs. The chemicals used in the process are highly toxic and therefore pose major threats to humans and environment. This proposal outlines the first attempts to develop a new and innovative hybrid organic-inorganic nanocomposite material to replace the copper plating and chrome coating. The success of the project will offer high quality, affordable and environmentally friendly printing service to both local and international clientele.
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3D integrated crystalline UV optical lens-fiber couplers for astronomy. This project aims to create micro-optics for astronomical and bio medical applications by 3D sculpturing them out of crystals by ultra-short pulse lasers. This project will introduce a new 3D fabrication approach of optical probes which have self-aligned micro-optical elements and optical fibres for a wide spectral range and with high quality optical surfaces. Expected outcomes of this project include building new capabiliti ....3D integrated crystalline UV optical lens-fiber couplers for astronomy. This project aims to create micro-optics for astronomical and bio medical applications by 3D sculpturing them out of crystals by ultra-short pulse lasers. This project will introduce a new 3D fabrication approach of optical probes which have self-aligned micro-optical elements and optical fibres for a wide spectral range and with high quality optical surfaces. Expected outcomes of this project include building new capabilities in micro-optical probes for industrial environments, establishing new solutions for international astronomy partners, and developing new techniques to image through optical fibres. This should provide significant benefits by improving astronomical instrumentation and also lead to less invasive endoscopy.Read moreRead less
Advanced lanthanide-doped nanomaterials for new-generation security inks. Current security labelling technologies using pattern coding (“barcoding”) and/or UV-excited phosphorescent inks are relatively easily counterfeited. The project aims to identify optimal design, fabrication and surface treatment of infrared-excited lanthanide nanoparticles for use as pigments in UV-curable polymer inks. This is expected to result in a new-generation of jet-printable security inks with ultimate capability f ....Advanced lanthanide-doped nanomaterials for new-generation security inks. Current security labelling technologies using pattern coding (“barcoding”) and/or UV-excited phosphorescent inks are relatively easily counterfeited. The project aims to identify optimal design, fabrication and surface treatment of infrared-excited lanthanide nanoparticles for use as pigments in UV-curable polymer inks. This is expected to result in a new-generation of jet-printable security inks with ultimate capability for multidimensional coding (using multiple luminescence wavelengths and lifetimes) and robust readability. Expected outcomes are world leadership in codable inks for secure labelling against counterfeiting, greatly enhancing both global ink-product sales and the value of Australian exports subject to product substitution.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100068
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This pr ....Bioinspired liposome-based smart sensors. This project aims to develop a liposome-based biosensor technology that mimics cell sensory systems. Selective detection of compounds is increasingly important for food, health and environmental monitoring. Biosensor development faces long-standing challenges such as response time, sensitivity, specificity, and multiplexing. On the other hand, cells can sense and discriminate multiple biomolecules in seconds with high sensitivity and specificity. This project aims to harness cells’ exquisite biological properties to improve current detection techniques. It will integrate liposome-based sensors with microfluidics to perform analytical tasks ranging from food safety to diagnostics.Read moreRead less
Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cos ....Nanoarchitectured multifunctional porous superparamagnetic nanoparticles. This project aims to develop a method for the direct detection of biomarkers based on a new class of highly porous superparamagnetic nanoparticles with peroxidase-like activity. The particles will be used as dispersible capture agents for isolating specific targets in biological samples, and electrocatalytic nanozymes for naked-eye evaluation and electrochemical detection. The project is expected to develop simple, low-cost, portable devices for the analysis of exosomes and exosomal miRNA in biological samples. The future development of this technology into diagnostic devices will improve patient outcomes by enabling earlier disease diagnosis and improved monitoring of treatment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100073
Funder
Australian Research Council
Funding Amount
$468,474.00
Summary
Nanoimprint systems: expanding research capability of roll to roll printer. This project aims to strengthen Australian research activities in the development of advanced multifunctional materials through the purchase of thermal and ultraviolet (UV) nano-imprint lithography modules to expand the nanofabrication capacity of roll-to-roll printer line. The various processes used to make nano-sized devices and components fall into two major categories, coating and patterning. Integrating the thermal ....Nanoimprint systems: expanding research capability of roll to roll printer. This project aims to strengthen Australian research activities in the development of advanced multifunctional materials through the purchase of thermal and ultraviolet (UV) nano-imprint lithography modules to expand the nanofabrication capacity of roll-to-roll printer line. The various processes used to make nano-sized devices and components fall into two major categories, coating and patterning. Integrating the thermal and UV nanoimprint lithography modules into the roll-to-roll printer line will provide a unique and simple materials fabrication platform. It will combine coating and nanolithography processes in a low cost, high-throughput and high-resolution format for advanced nanofabrication of microelectronic, telecommunication, biomedical and energy devices.Read moreRead less
Seeing is believing: Microscopy-capable single-molecule bioelectronics. This project aims to create new biophysical tools for single-molecule sensing by advancing the state-of-the-art in nanoscale bioelectronic devices. The goal is to generate novel bioelectronic devices optimised for fabrication on microscope coverslip (170 micron glass) for compatibility with new low-cost platforms for advanced biological microscopy. Expected outcomes include the first organic electrochemical transistors inter ....Seeing is believing: Microscopy-capable single-molecule bioelectronics. This project aims to create new biophysical tools for single-molecule sensing by advancing the state-of-the-art in nanoscale bioelectronic devices. The goal is to generate novel bioelectronic devices optimised for fabrication on microscope coverslip (170 micron glass) for compatibility with new low-cost platforms for advanced biological microscopy. Expected outcomes include the first organic electrochemical transistors interfaced to constrained area lipid bilayers for studying membrane proteins at single-molecule level and nanoscale transistors for electrostatically detecting motile microtubules in in-vitro molecular motor assays for biocomputation. The intended benefit is innovation in capabilities and manufacturing of bioelectronics.Read moreRead less
Trapping and Watching Biomolecular Complexes near Nanopores. This project aims to develop a technology to trap and interrogate nanosized molecular complexes in their natural state. Nanosized complexes in water provide the core machinery of biological systems and require detailed understanding to help unravel fundamental biological mechanisms. A prototype of a methodology has been developed to trap and interrogate nanoscaled objects as small as 190 nanometres within a nanopore device. By performi ....Trapping and Watching Biomolecular Complexes near Nanopores. This project aims to develop a technology to trap and interrogate nanosized molecular complexes in their natural state. Nanosized complexes in water provide the core machinery of biological systems and require detailed understanding to help unravel fundamental biological mechanisms. A prototype of a methodology has been developed to trap and interrogate nanoscaled objects as small as 190 nanometres within a nanopore device. By performing research to fully understand, miniaturise and develop this method further, this project aims to enable the quantitative observation of nanoscaled biological machinery involved in cell-to-cell communication and DNA unfolding. Such a technology platform may have applications in areas such as biology, biotechnology and advanced materials.Read moreRead less
Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the r ....Cell Membrane Coated Photonic Crystal to study Receptor-Ligand Interactions. The current gold-standard assays for examining receptor-ligand interactions require expensive and costly fluorescent or radioactive labels or proteomics processes. This project aims to develop Artificial Photonic Cells by directly coating photonic crystals with cell membranes. The Artificial Photonic Cells retain the protein receptors in their native cell membrane environment and allow for label-free monitoring of the receptor-ligand interactions using inexpensive miniature spectrometers - radically transforming these assays. This would generate fundamental and applied knowledge of materials sciences, photonic, and biointerfaces for label-free, ultra-sensitive, and selective assays to enable future drug and diagnostics target discovery. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100174
Funder
Australian Research Council
Funding Amount
$425,000.00
Summary
X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally ....X-Ray Nanolithography Facility: Towards the ultimate resolution. This Project aims to address the need for precise and scalable nanoscale fabrication by establishing a synchrotron-based X-Ray Nanolithography Facility. This Project expects to generate new knowledge in the areas of advanced manufacturing and nanotechnology using an innovative approach that combines coherent lithography and coherent imaging metrology. Expected outcomes of this project include an internationally unique, nationally accessible capability for manufacturing at the nanoscale and for industry-driven collaborative research. This should provide significant benefits across fields that aim to harness the unique properties of engineered nanomaterials to greatly enhance the technologies required to solve global challenges.Read moreRead less