A Randomized Clinical Trial Comparing Effectiveness Of 4RIF And 9INH For Treatment Of Latent TB Infection
Funder
National Health and Medical Research Council
Funding Amount
$496,875.00
Summary
Treatment of latent tuberculosis infection (LTBI) is one intervention that is known to prevent the occurrence of active TB. Current treatment is based on a six to nine month course of isoniazid. The treatment has side effects in some people and many people do not complete the treatment. The present study is to test an alternative treatment regimen (4 months of rifampicin) which has fewer side-effects and is more likely to be completed.
Maximising The Effectiveness Of Interactive Automated Programs For Smoking Cessation
Funder
National Health and Medical Research Council
Funding Amount
$922,582.00
Summary
This project is to design, implement and trial automated programs to help smokers quit. It makes use of the powers of modern computing and telecommunications. It uses information the person provides to personally tailor advice and assistance to smokers as they progress from beginning to think about quitting through to being a stable, happy non-smoker. In particular, we are interested in the relative value of detailed advice as compared with the capacity of modern messaging technology (SMS, voice ....This project is to design, implement and trial automated programs to help smokers quit. It makes use of the powers of modern computing and telecommunications. It uses information the person provides to personally tailor advice and assistance to smokers as they progress from beginning to think about quitting through to being a stable, happy non-smoker. In particular, we are interested in the relative value of detailed advice as compared with the capacity of modern messaging technology (SMS, voice, images) to provide a set of prompts and reminders that help smokers manage a quit attempt and help prevent them relapsing back to smoking. Once we have developed the interventions, we will subject them to a rigorous scientific trial to see how effective they are and also how cost-effective they prove. Our hope is that these programs will provide a cheap, accessible and effective way of helping smokers to quit and thus help reduce the huge toll of smoking-related disease.Read moreRead less
Improving the performance of Australian social insurance schemes. Applying methods from computational social science, this project aims to develop a novel, multi-level modeling framework to assist transport injury, workplace injury and disability insurance schemes consistently achieve and maintain standards of high performance as recognised by international benchmarks. By creating a virtual laboratory for policy-makers and scheme managers, it expects to generate a comprehensive understanding of ....Improving the performance of Australian social insurance schemes. Applying methods from computational social science, this project aims to develop a novel, multi-level modeling framework to assist transport injury, workplace injury and disability insurance schemes consistently achieve and maintain standards of high performance as recognised by international benchmarks. By creating a virtual laboratory for policy-makers and scheme managers, it expects to generate a comprehensive understanding of mechanisms driving insurance scheme performance, enabling comparison of anticipated outcomes in response to legislative changes, policy changes and management decisions. The project aims to help schemes avoid human and financial failure, benefitting people with injuries and disabilities while reducing scheme costs.Read moreRead less
A New Direction For TB Control In Highly Endemic Countries: A RCT Of Active Case Finding
Funder
National Health and Medical Research Council
Funding Amount
$1,362,910.00
Summary
Tuberculosis is the number 1 health problem in Vietnam . Many people with TB do not know they have the disease but are infectious to others. Hence, the disease continues to spread. This project will investigate the role of x-ray screening to detect and treat more people with TB, particularly those who do not have symptoms. This may be an important element of future TB control programs in Vietnam and elsewhere in our region.
Determining The Impact Of Opioid Substitution Therapy Upon Mortality And Recidivism Among Prisoners: A 22-year Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$354,114.00
Summary
This study will quantify the impact of opioid substitution therapy (OST; methadone or buprenorphine) on two important outcomes for opioid dependent prisoners: mortality, particularly in the post-release period; and subsequent criminal activity. The study will have almost 600,000 person-years of follow-up over 22 years, allowing fine grained analyses of disadvantaged subpopulations. The study has clear implications for the health of this population, crime reductions, and cost savings.
Software Quality Improvement Through Static Analysis and Annotation. Software forms the basis of critical infrastructure that supports industries such as electronic commerce. Flaws in the software can lead to failure of the overall system, or allow the security mechanisms of the software to be by-passed. This project is developing methods to improve the quality of software by finding common flaws that lead to security vulnerabilities or runtime failures. Within Australia, it is estimated that th ....Software Quality Improvement Through Static Analysis and Annotation. Software forms the basis of critical infrastructure that supports industries such as electronic commerce. Flaws in the software can lead to failure of the overall system, or allow the security mechanisms of the software to be by-passed. This project is developing methods to improve the quality of software by finding common flaws that lead to security vulnerabilities or runtime failures. Within Australia, it is estimated that there are approximately 75,000 software developers who make substantial use of C/C++ and who could benefit from the availability of better automatic static analysis tools to improve both the quality of the code they produce and their productivity.Read moreRead less
National Non-human Primate Breeding And Research Facility
Funder
National Health and Medical Research Council
Funding Amount
$2,640,742.00
Summary
Some biomedical research is best undertaken on primates, in order to allow the greatest relevance to understanding health and disease in humans. Examples of such research include studies into diseases like HIV-AIDS and much of the research into understanding the human brain and nervous system. The National Health and Medical Research Committee (NHMRC), through its Animal Welfare Committee, has taken an international leadership position in ensuring that any non-human primates used for biomedical ....Some biomedical research is best undertaken on primates, in order to allow the greatest relevance to understanding health and disease in humans. Examples of such research include studies into diseases like HIV-AIDS and much of the research into understanding the human brain and nervous system. The National Health and Medical Research Committee (NHMRC), through its Animal Welfare Committee, has taken an international leadership position in ensuring that any non-human primates used for biomedical research are bred and housed in the best possible facilities and looked after with the highest level of care available. To ensure this quality of care, it is NHMRC policy to only use animals that have been bred and reared specifically for research purposes. The National Non-Human Primate Breeding and Research Facility, hosted by Monash University, ensures that Australian community has access to macaque monkeys and marmosets to carry out research under the highest quality conditions. Additionally the colonies will provide a key resource in any national response to pandemics and bioterrorism for vaccine and response development.Read moreRead less