Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent co ....Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent corruption and other integrity violations; coordinate the work of integrity institutions; ensure their accountability; and measure the effectiveness of integrity and anti-corruption policy settings. This research is expected to contribute to better evaluation of integrity policies worldwide.Read moreRead less
Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems ....Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems analyses of dark net forums, and bringing together researchers, practitioners, theories and methods from human factors, sociotechnical systems, criminology, and cyber security—is expected to increase understanding of the dark net and improve ways of disrupting identity theft and trading.Read moreRead less
Reducing antibiotic usage in pig herds: controlling Lawsonia intracellularis by vaccination, housing and hygiene. Pigs are major consumers of antibiotics in Australia. Many of these antibiotics are fed to pigs to prevent proliferative enteritis (PE). There are increasing public concerns regarding the development and spread of antibiotic-resistant bacteria and the potential impact on human health. The adoption of an effective commercial vaccine to prevent PE will reduce the volume of antibiotics ....Reducing antibiotic usage in pig herds: controlling Lawsonia intracellularis by vaccination, housing and hygiene. Pigs are major consumers of antibiotics in Australia. Many of these antibiotics are fed to pigs to prevent proliferative enteritis (PE). There are increasing public concerns regarding the development and spread of antibiotic-resistant bacteria and the potential impact on human health. The adoption of an effective commercial vaccine to prevent PE will reduce the volume of antibiotics used in the pig industry and hence reduce the risk of antibiotic-resistant bacteria developing.Read moreRead less
Development of an anti-Chlamydia vaccine for the koala. The koala is one of Australia's main icons and a major drawcard for tourists. However, it suffers from debilitating disease due to the bacterium Chlamydia, which can lead to severe conjunctivitis, eventual blindness in both sexes, and the females develop untreatable cysts and can become infertile. This project will develop a Chlamydia vaccine to be administered to healthy and diseased koalas in zoos, sanctuaries, koala care centres, relocat ....Development of an anti-Chlamydia vaccine for the koala. The koala is one of Australia's main icons and a major drawcard for tourists. However, it suffers from debilitating disease due to the bacterium Chlamydia, which can lead to severe conjunctivitis, eventual blindness in both sexes, and the females develop untreatable cysts and can become infertile. This project will develop a Chlamydia vaccine to be administered to healthy and diseased koalas in zoos, sanctuaries, koala care centres, relocation programs and eventually perhaps even wild populations. The vaccine findings may also be transferable to other animals and may also even assist the development of a human Chlamydia vaccine.Read moreRead less
Oxide Bioceramics for Drug Delivery. Australia has the highest rate of skin cancer in the world. One out of every two Australians will develop skin cancer at some stage during their lives. On average, 740,000 new cases of skin cancer are diagnosed in Australia every year (1 million in the USA). The cost to Australia is over $200 million/year. While today more people are aware of the dangers of UV, the desire to be fashionable outweighs their health concerns. Melanotan is a novel sunscreen soluti ....Oxide Bioceramics for Drug Delivery. Australia has the highest rate of skin cancer in the world. One out of every two Australians will develop skin cancer at some stage during their lives. On average, 740,000 new cases of skin cancer are diagnosed in Australia every year (1 million in the USA). The cost to Australia is over $200 million/year. While today more people are aware of the dangers of UV, the desire to be fashionable outweighs their health concerns. Melanotan is a novel sunscreen solution: a drug that stimulates the body's natural defence mechanism against UV light. Alumina and zirconia bioceramics are ideal implantable drug delivery vehicles because of the long leaching periods possible.Read moreRead less
Molecular and antibody analysis of cytomegalovirus (CMV) infection of fetal and placental cells. CMV is a beta herpesvirus with many unknown molecular mechanisms associated with cellular infection. The virus infects placental cells in vivo, although pathogenesis of viral damage to these cells has been extremely difficult to study in vitro. We have commenced a study to i) demonstrate the molecular accompaniments of infection of placental cells in vitro, ii) determine the genotypic characteristics ....Molecular and antibody analysis of cytomegalovirus (CMV) infection of fetal and placental cells. CMV is a beta herpesvirus with many unknown molecular mechanisms associated with cellular infection. The virus infects placental cells in vivo, although pathogenesis of viral damage to these cells has been extremely difficult to study in vitro. We have commenced a study to i) demonstrate the molecular accompaniments of infection of placental cells in vitro, ii) determine the genotypic characteristics of congenital CMV infections, in collaboration with Abbott Diagnostics, and iii) produce an in vivo model of CMV infection to demonstrate the pathogenesis of cellular injury. The combination of molecular expertise at UNSW with monoclonal antibody expertise from Abbott Diagnostics mean this project is unique worldwide.Read moreRead less
Targeted crime: policing and social inclusion. This project will undertake a criminological study of the policing of targeted incidents and crime, that is, incidents and crimes motivated by bias, prejudice or hatred towards members of particular groups, communities and individuals. It will develop a best practice policing framework for targeted crimes and incidents.
Oral Delivery - A Viable Strategy for Fertility Control Vaccination of Kangaroos ? Local overabundance of kangaroos poses significant, environmental, economic, social and animal welfare problems in Australia. The only management tool available for free ranging populations is shooting. Fertility control is a highly desirable alternative but current 'hands on' methods are not cost-effective options for wild populations. Immunologically-mediated contraception has the potential to be such a manag ....Oral Delivery - A Viable Strategy for Fertility Control Vaccination of Kangaroos ? Local overabundance of kangaroos poses significant, environmental, economic, social and animal welfare problems in Australia. The only management tool available for free ranging populations is shooting. Fertility control is a highly desirable alternative but current 'hands on' methods are not cost-effective options for wild populations. Immunologically-mediated contraception has the potential to be such a management tool if the vaccine can be delivered effectively. The investigators and their colleagues have achieved contraception by vaccine injection in kangaroos. This project aims to establish proof-of-concept for arguably the only viable vaccine delivery option for free ranging macropods: Oral delivery via an edible pellet or lick.Read moreRead less
Nanophotonic metamaterials as anti-counterfeit devices in Australian banknotes. This project will demonstrate the application of novel materials as the basis for next generation security features on banknotes. Such elements play a key role in maintaining the integrity of Australia's currency since they present a significant barrier to counterfeiting.
Biological phosphorous removal for wastewater treatment. The aim is to provide a scientific basis for understanding how phosphorous can be removed in wastewater treatment plants, using environmentally safe biological methods rather than by using chemicals. This is expected to lead to improved performance in wastewater treatment plants, which will be of economic and environmental benefit, particularly to regional communities in inland Australia.