Development Of A Take-home Rehabilitation Device That Improves Visual Stability And Balance In Patients With Peripheral Vestibular Injury
Funder
National Health and Medical Research Council
Funding Amount
$789,377.00
Summary
The balance system senses head motion via the balance organs, one in each inner ear, and stabilises vision during head movements. Without it, every time you walk, run, or drive on a bumpy road, the world appears to bounce. We have developed a device shown to reliably 'train up' the balance system. Our aim is to develop this device further for effective take-home rehabilitation.
Preclinical Development Of Q2361, A Transforming New Drug For Skin Cancer Prevention In Organ Transplant Recipients
Funder
National Health and Medical Research Council
Funding Amount
$724,957.00
Summary
Patients that receive organ transplants need additional medications in order to prevent organ rejection. Unfortunately, these drugs carry an unwanted side-effect - they permit the development of skin cancer. Currently, other than surgery, little can be done to help these patients. Our preliminary data suggest that a new drug may prevent these skin cancers from forming. This project aims to deliver key insights into the influence of this drug and its role in skin cancer prevention.
A portable device that can measure glycosylated haemoglobin (HbA1c) in the home will be developed. HbA1c is an important biomarker of the average blood glucose levels over the preceding three months and hence guides a diabetic regarding their blood glucose treatment regime. A 1% decrease in HbA1c levels is associated with a dramatic decrease in chronic health complications from diabetes. The HbA1c meter that will be developed will be able to operate with existing glucose meter technologies.
The aim of this proposal is to test the safety of a novel immunotherapy based on Helicobacter pylori platform technology to treat childhood allergies. Repeated oral administration of killed H. pylori mimics colonisation in the stomach and assists the development of a balanced immune system without the associated disease risk of live H. pylori. To achieve this goal Professor Barry Marshall has assembled a cross-disciplinary team of experts from Industry, Academia and Clinic.
Development Of A Blood-based Screening Test For Colorectal Neoplasia; Biomarker Expression In Circulating Tumor Cells And Tumor-derived Microvesicles
Funder
National Health and Medical Research Council
Funding Amount
$513,938.00
Summary
A blood-based test for bowel cancer and the premalignant lesion (i.e. adenomas) has potential to improve several aspects of screening for bowel cancer – improved capacity to detect lesions in well people who do not suspect their presence, avoidance of faecal sampling and fewer false-positive results. There is no reliable simple screening test for adenomas. This study aims at developing a practical blood test based on a device that filters and enriches cells from blood that carry these markers