When Prometheus Needs A Hand – How Human Amnion Epithelial Cells Resolve Fibrosis And Regenerate The Liver
Funder
National Health and Medical Research Council
Funding Amount
$530,653.00
Summary
Cirrhosis can progress to end stage disease for which transplantation provides the only hope for survival. Liver donors in Australia are scarce; the need for donor organs is increasing. Using stem cells to repair and regenerate damaged liver may provide an alternative to organ transplantation. We are studying placental stem cells that can decrease inflammation and increase progenitor cells to repair and regenerate liver. Our goal is to use these stem cells as treatment for human liver disease
Aboriginal and non-Aboriginal sex-offenders in Australia: Assessing risk for practice and policy. A key priority of Australian governments is to improve community safety through reducing the risk of sex offenders re-offending after release from prison. This project will assess the validity of tools used to predict the risk of sexual offender recidivism and identify alternate risk assessment tools for Indigenous and non-Indigenous sex offenders.
Understanding The Acute And Cumulative Metabolic Effects Of Prolonged Sitting In Adults
Funder
National Health and Medical Research Council
Funding Amount
$416,597.00
Summary
Sedentary behaviour (sitting time) has been linked to an increased risk of chronic illnesses, including type 2 diabetes and obesity, but recent evidence suggests that light-intensity activity (non-exercise activities of daily living) is associated with reduced risk. These studies will examine whether breaking up sitting time with frequent short periods of activity can overcome the negative effects of prolonged sitting on blood glucose and blood fats in overweight older adults.
Better Planning for and Managing Asymmetric Threats to Australia's Security: Applying the Field Anomaly Relaxation (FAR) Systems Thinking Approach. Despite an enviable national security condition, Australia is at risk in an information-abundant world that increasingly spawns asymmetric threats such as information terrorism. What is needed are enhanced strategic and operational structures to improve the nation's security and ensure sound futures planning. This research focuses on applying the Fie ....Better Planning for and Managing Asymmetric Threats to Australia's Security: Applying the Field Anomaly Relaxation (FAR) Systems Thinking Approach. Despite an enviable national security condition, Australia is at risk in an information-abundant world that increasingly spawns asymmetric threats such as information terrorism. What is needed are enhanced strategic and operational structures to improve the nation's security and ensure sound futures planning. This research focuses on applying the Field Anomaly Relaxation (FAR) systems thinking approach to asymmetric information warfare threats to Australia. This is a new approach previously developed by ECU researchers investigating risk and innovation in the armed forces. It will now be extended to improve professional practice and the knowledge and skill base of Australia's information defence practitioners.Read moreRead less
Improving social and economic outcomes for children of incarcerated mothers. This project aims to identify how children’s experiences of maternal incarceration shape their life course. These children are one of the most vulnerable yet invisible groups in society and are rising in number. This project intends to interrogate system contact with child protection, justice, education and health agencies using a unique linked dataset across 30 years and over three generations, to describe social and e ....Improving social and economic outcomes for children of incarcerated mothers. This project aims to identify how children’s experiences of maternal incarceration shape their life course. These children are one of the most vulnerable yet invisible groups in society and are rising in number. This project intends to interrogate system contact with child protection, justice, education and health agencies using a unique linked dataset across 30 years and over three generations, to describe social and economic outcomes and how prison, child and maternal characteristics affect them. The project expects to provide critical evidence that can inform prevention strategies, with the potential to disrupt intergenerational patterns of profound disadvantage and reduce the social and economic costs of maternal incarceration to individuals and society.Read moreRead less
View and shape invariant modeling of human actions for smart surveillance. This project aims to enable surveillance cameras to interpret videos and detect unexpected activity in real time. Existing surveillance cameras are unable to interpret videos. Because most are not monitored in real time, they play no role in improving security response time. The project plans to develop algorithms to detect actions from any camera viewpoint in continuous videos, a capability that is imperative for smart s ....View and shape invariant modeling of human actions for smart surveillance. This project aims to enable surveillance cameras to interpret videos and detect unexpected activity in real time. Existing surveillance cameras are unable to interpret videos. Because most are not monitored in real time, they play no role in improving security response time. The project plans to develop algorithms to detect actions from any camera viewpoint in continuous videos, a capability that is imperative for smart surveillance yet missing in current techniques. This would improve security and safety response time to events that need immediate attention, such as crimes and medical emergencies, and offer autonomous aids to elderly care, smart homes, child minding, patient monitoring and post-trauma rehabilitation.Read moreRead less
Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women ....Reducing young women’s offending through improved service delivery . Young women’s contact with justice and welfare agencies has increased rapidly across Australia and the world, creating a crisis that is costly and harmful, especially for young Indigenous women. Pathways into these systems are gendered; but the systems were designed to address the needs of young male offenders. This project therefore aims to discover how these systems could be better designed to improve outcomes for young women. The project uses a novel approach that gives young women a voice in how five Anglicare end-users (the research partners) and other end-users can enhance their service provision in the welfare and justice sectors and become models of best practice.Read moreRead less
Regulation of Indigenous Safety Strategies: Night Patrols & Policy. This project aims to identify the qualities that make Indigenous night patrols (NPs) unique, to inform and improve the capacities of agencies and regulatory authorities and indigenous communities to work together, leading to greater security, peace and safety. Crime and safety in Aboriginal communities remains a major concern. NPs, an Australian innovation developed by Aboriginal communities, have become key players in local cri ....Regulation of Indigenous Safety Strategies: Night Patrols & Policy. This project aims to identify the qualities that make Indigenous night patrols (NPs) unique, to inform and improve the capacities of agencies and regulatory authorities and indigenous communities to work together, leading to greater security, peace and safety. Crime and safety in Aboriginal communities remains a major concern. NPs, an Australian innovation developed by Aboriginal communities, have become key players in local crime reduction strategies, and carry the endorsement of both government and Aboriginal communities. However, they are operating in an environment of increased ‘top-down’ control and regulation. Does greater accountability to government weaken NP’s ‘cultural’ accountability to communities? This project explores the qualities that make NPs unique. This includes the prominent, and neglected, role of Indigenous women as patrollers and clients, who may lose out should NPs become like mainstream community safety mechanisms.Read moreRead less
Remediation of Underground Contaminant Source Areas using Nano-scale, Zero Valent Iron and Potassium Permanganate. Land in parts of Australia valued in the hundreds of millions of dollars is currently contaminated by organic compounds to levels unsuitable for human health and safety . At many of these contaminated sites, the contamination is present as pure, separate phase oil that is trapped due to geology or other physical reasons. This remaining oil is a long term source of contamination, a ....Remediation of Underground Contaminant Source Areas using Nano-scale, Zero Valent Iron and Potassium Permanganate. Land in parts of Australia valued in the hundreds of millions of dollars is currently contaminated by organic compounds to levels unsuitable for human health and safety . At many of these contaminated sites, the contamination is present as pure, separate phase oil that is trapped due to geology or other physical reasons. This remaining oil is a long term source of contamination, and is exceptionally difficult to remediate. The proposed research will investigate a novel and highly effective approach to destroying this contamination in the ground, helping to restore the value and utility of the land.Read moreRead less
The identification, prevention and management of chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises a number of research methods to advance our understanding and provide new directions for cardiovascular disease prevention and management.