The feasibility, acceptability and cost-effectiveness of nurse-led models of chronic disease management in general practice. This study directly relates to the National Research Priority of 'promoting and maintaining good health' through our approach to trial a new and innovative model of chronic disease management specifically for CVD and Type II diabetes in general practice. This project aims to test a new model of health service delivery - that is, the use of a practice nurse to provide chro ....The feasibility, acceptability and cost-effectiveness of nurse-led models of chronic disease management in general practice. This study directly relates to the National Research Priority of 'promoting and maintaining good health' through our approach to trial a new and innovative model of chronic disease management specifically for CVD and Type II diabetes in general practice. This project aims to test a new model of health service delivery - that is, the use of a practice nurse to provide chronic disease care rather than a general practitioner. Our strategy involves collaboration with health providers, stakeholders and consumers to help achieve this by providing patient education and disease management through a registered nurse in general practice.Read moreRead less
Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic ....Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic wounds are associated with significant hidden burdens on the community resulting from loss of mobility, decreased functional ability, social isolation and loss of participation in the workforce/society. This study will provide much needed information on management of this chronic disease to promote improved quality of life, health and independence in this population.Read moreRead less
From Suspician to Intervention : Improving responsiveness to abuse of the elderly in acute and sub-acute health care. Early identification of risk and an integrated multidisciplinary response across the health service would be effective in responding to the multiple and complex behavioural and social issues which contribute to aged abuse as it presents in emergency, acute and sub-acute care, but are currently often ignored in health services and the literature. We propose that effective use of ....From Suspician to Intervention : Improving responsiveness to abuse of the elderly in acute and sub-acute health care. Early identification of risk and an integrated multidisciplinary response across the health service would be effective in responding to the multiple and complex behavioural and social issues which contribute to aged abuse as it presents in emergency, acute and sub-acute care, but are currently often ignored in health services and the literature. We propose that effective use of this "window of opportunity in health care" could extend the level of community response to this vulnerable group of people. Read moreRead less
The use of social marketing strategies and adult education principles to improve asthma self management in older people. Asthma is estimated to affect up to 10 per cent of people aged 65+ some of whom experience the condition for the first time later in life. Mortality rates from asthma in Australia are highest in the older population and statistics show that older people are most likely to be admitted to hospital following attendance at an Emergency Department for asthma. Older people lack aw ....The use of social marketing strategies and adult education principles to improve asthma self management in older people. Asthma is estimated to affect up to 10 per cent of people aged 65+ some of whom experience the condition for the first time later in life. Mortality rates from asthma in Australia are highest in the older population and statistics show that older people are most likely to be admitted to hospital following attendance at an Emergency Department for asthma. Older people lack awareness about asthma, often manage it poorly, and their health related quality of life is impacted by asthma. There is disparity in asthma information, management and service provision targeted specifically to the needs of the elderly. This project will provide much-needed evidence on the effectiveness of carefully researched and targeted programs for older asthmatics.Read moreRead less
Economic and Social Benefits of treating and preventing influenza in Aged Care Facilities. Influenza is a deadly issue for the elderly, their carers and the community. It reduces quality of life and productivity through hospitalisation and work absenteeism. By preventing influenza using an antiviral drug for residents and staff in aged care facilities there should be considerable economic and social benefits. This controlled scientific experiment will determine how much disease and death can be ....Economic and Social Benefits of treating and preventing influenza in Aged Care Facilities. Influenza is a deadly issue for the elderly, their carers and the community. It reduces quality of life and productivity through hospitalisation and work absenteeism. By preventing influenza using an antiviral drug for residents and staff in aged care facilities there should be considerable economic and social benefits. This controlled scientific experiment will determine how much disease and death can be averted and provide real data that is critical to planning for an influenza pandemic. It will direct where emphasis should be placed between the control measures of infection control (eg hand-washing, masks), vaccination and use of antiviral drugs. Annual outbreaks will be curtailed.Read moreRead less
Discovery Indigenous Researchers Development - Grant ID: DI0560757
Funder
Australian Research Council
Funding Amount
$160,896.00
Summary
Identification and Characterisation of Genes involved in the Copper Regulation of the Human Alzheimer's Disease Amyloid-Beta Precursor Protein (APP) Gene. Alzheimer's disease (AD) is the most common form of dementia in the ageing population. This research project aims to identify and characterise new genes involved in the copper regulation of the Alzheimer's disease gene. This may lead to the development of novel therapeutic targets and clinical intervention strategies as well as early diagnost ....Identification and Characterisation of Genes involved in the Copper Regulation of the Human Alzheimer's Disease Amyloid-Beta Precursor Protein (APP) Gene. Alzheimer's disease (AD) is the most common form of dementia in the ageing population. This research project aims to identify and characterise new genes involved in the copper regulation of the Alzheimer's disease gene. This may lead to the development of novel therapeutic targets and clinical intervention strategies as well as early diagnostic procedures in preventative healthcare for the treatment of AD. The benefits would affect the international community as a whole, potentially minimising the socio-economic costs arising from the predicted world-wide increase in AD in the ageing population.Read moreRead less
New fermentation and purification production technologies for menaquinone-7 for promoting bone and cardiovascular health. We will develop a significantly more cost-efficient and environmentally friendly process for the production of vitamin K (menaquinone-7, or MK7) to manufacture food supplements for humans and animals. MK7 will increase bone regeneration and minimise the risk of cardiovascular disease. It has the potential to reduce the costs of these conditions for the community, and to incre ....New fermentation and purification production technologies for menaquinone-7 for promoting bone and cardiovascular health. We will develop a significantly more cost-efficient and environmentally friendly process for the production of vitamin K (menaquinone-7, or MK7) to manufacture food supplements for humans and animals. MK7 will increase bone regeneration and minimise the risk of cardiovascular disease. It has the potential to reduce the costs of these conditions for the community, and to increase the quality of life for Australia's ageing population. Orthopaedic diseases are also a major veterinary issue, and our advance should make MK7 a more widely used available supplementary food for animals such as horses and dogs. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453623
Funder
Australian Research Council
Funding Amount
$164,640.00
Summary
Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in re ....Peripheral quantitative computed tomography facility for analysing bone material and structural properties. We aim to establish a facility that allows non-invasive measurement of apparent material and structural properties of small animal and human bone using leading-edge technology, peripheral quantitative computed tomography (pQCT). pQCT measurements, incorporated into our fundamental bone research will improve our understanding of the role of mechanical, environmental and local factors in regulating bone and mineral metabolism and altering bone properties. This has implications for maximising bone strength and promoting optimal health throughout life. The facility will be used for a diverse range of multidisciplinary basic bone research and is vital in order to maintain international competitiveness in the field.Read moreRead less
Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage. A deficiency in the protein haem oxygenase-1 causes severe biological consequences in animals and humans. These include decreased reproduction, retarded development, the inability of the body to handle iron, chronic inflammation and increased susceptibility to age-associated diseases. This study will determine how a deficiency of the protein alters cells at the level of genes, proteins and protein function ....Cellular Responses to Adversity: Oxidative Stress and Protection Against Oxidative Damage. A deficiency in the protein haem oxygenase-1 causes severe biological consequences in animals and humans. These include decreased reproduction, retarded development, the inability of the body to handle iron, chronic inflammation and increased susceptibility to age-associated diseases. This study will determine how a deficiency of the protein alters cells at the level of genes, proteins and protein functions. By doing so, the project will illuminate how haem oxygenase-1 alters cell functions in a beneficial way. This information will eventually assist in preventing the serious disorders associated with deficiency of haem oxygenase-1. It will also provide the basis for novel treatments to slow down age-associated diseases.Read moreRead less
Increasing and Sustaining Physical Activity Levels of Sedentary Older Adults by Improving Social Support and Links with Local Community Resources. This project will promote the health of older people by linking them with local physical activity resources and social support to encourage them to increase and sustain their levels of physical activity. This project uses an innovative approach to tackle one of the key behavioural risk factors for older people, namely physical inactivity, identified b ....Increasing and Sustaining Physical Activity Levels of Sedentary Older Adults by Improving Social Support and Links with Local Community Resources. This project will promote the health of older people by linking them with local physical activity resources and social support to encourage them to increase and sustain their levels of physical activity. This project uses an innovative approach to tackle one of the key behavioural risk factors for older people, namely physical inactivity, identified by the national ageing strategy. The intervention model will provide, for the first time, a sustainable local community vehicle for engaging and sustaining sedentary older people in physical activity. It is anticipated that the community will adopt the model once its efficacy is demonstrated.Read moreRead less