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Phase III Trial Of Radical Chemo-radiation Vs Radiation Alone In The Management Of Localised Bladder TCC.
Funder
National Health and Medical Research Council
Funding Amount
$194,875.00
Summary
This trial aims to see if the combination of Chemotherapy and Radiation treatment is indeed superior in eradicating the tumor and preserving the Bladder in a greater number of patients as compared to Radiation treatment alone. If the final results from this study do show chemoradiotherapy to be significantly superior to radiation alone, without an increase in morbidity ( especially long term side effects ) , this may lay the platform for a greater proportion of patients with localised bladder ca ....This trial aims to see if the combination of Chemotherapy and Radiation treatment is indeed superior in eradicating the tumor and preserving the Bladder in a greater number of patients as compared to Radiation treatment alone. If the final results from this study do show chemoradiotherapy to be significantly superior to radiation alone, without an increase in morbidity ( especially long term side effects ) , this may lay the platform for a greater proportion of patients with localised bladder cancer, being in the first instance considered for this organ( bladder) preserving approach something which has become a reality at a number of other sites of cancer with the use of multimodality treatment.Read moreRead less
Ethnographic, Treatment, And Policy Responses To Patients Presenting For Care With Chronic Medically Unexplained Symptoms In Viet Nam: A Randomised Control Trial Of Cognitive Behaviour Therapy, Structured Care And Treatment As Usual
Funder
National Health and Medical Research Council
Funding Amount
$485,417.00
Summary
The current research will undertake a clinical trial of psychological treatments for medically unexplained symptoms (MUS) in Viet Nam. MUS have been identified as highly prevalent in Viet Nam and place a substantial burden on an under resourced health care sector. The research will help to advance international understandings of the MUS and their treatment and provide assistance to a country identified by the World Health Organisation mhGAP initiative for intensive mental health assistance.
The Role Of Trauma Related Anger And The Cycles Of Violence In Post Conflict Countries: A Follow Up Study In Timor Leste
Funder
National Health and Medical Research Council
Funding Amount
$560,618.00
Summary
Our 2004 East Timor study showed that men who suffered abuses remain angry. We will follow-up these men to see if those who remained angry were more likely to be involved in social unrest and violence. We will also find out what factors make angry men more likely to act violently. This study will provide information to help agencies assist men overcome anger to avoid future violence.
Why Do Australian Teenagers Fall Pregnant? Exploring The Antecedents Of Teenage Pregnancy.
Funder
National Health and Medical Research Council
Funding Amount
$542,100.00
Summary
Teenage pregnancy is a major health, social and economic issue for Australia. The teenage birth rate in Australia is higher than many other developed countries and of additional concern is the very high pregnancy and termination rate. Teenage pregnancy places the mother and child at greater risk of lifelong adverse outcomes. Despite research over more than 3 decades, we have only a simplistic understanding of what are likely complex mechanisms leading to early pregnancy. This is thought to be th ....Teenage pregnancy is a major health, social and economic issue for Australia. The teenage birth rate in Australia is higher than many other developed countries and of additional concern is the very high pregnancy and termination rate. Teenage pregnancy places the mother and child at greater risk of lifelong adverse outcomes. Despite research over more than 3 decades, we have only a simplistic understanding of what are likely complex mechanisms leading to early pregnancy. This is thought to be the reason for the failure of nearly all teenage pregnancy prevention efforts worldwide. In addition, there has been little study of this issue in Australian teenagers, and none in Aboriginal teenagers for whom pregnancy is more common and carries worse outcomes. This 2-stage project seeks to elucidate complex biological, psychological, and social pathways to unplanned pregnancy in the teenage years. In Phase 1, perceptions, values and beliefs will be explored in a qualitative study. Aboriginal and non-Aboriginal teenagers attending antenatal, termination and family planning clinics will be interviewed. Data from these interviews will generate new hypotheses regarding pregnancy risk in this age group. In Phase 2, 600 teenagers from schools, antenatal and termination clinics will be surveyed using computerised questionnaires. They will be asked about beliefs (identified in phase 1) and a range of other individual, family, and environmental factors identified in other studies to be risk factors for early pregnancy. Statistical analysis will be used to determine how multiple risk factors interact or combine to shape sexual and childbearing behaviour. This study will lead to new understandings of teenage pregnancy in Australia, and more effective teenage pregnancy intervention programs. Because few researchers in Australia, or elsewhere, have taken such a comprehensive approach to data collection and analysis, the results will be of international significance.Read moreRead less