Exploiting Database Technologies for the Visualization and Analysis of Measured and Simulated Plant Structures in Bioinformatics. The project will contribute to both bioinformatics and database research at both the national and international levels, although this project is specifically focusing on plant architecture but it has great potential other fields such as solving computationally difficult problems of branching in nature such as DNA and crystal related research. The results of this resea ....Exploiting Database Technologies for the Visualization and Analysis of Measured and Simulated Plant Structures in Bioinformatics. The project will contribute to both bioinformatics and database research at both the national and international levels, although this project is specifically focusing on plant architecture but it has great potential other fields such as solving computationally difficult problems of branching in nature such as DNA and crystal related research. The results of this research can be applied to all kinds of plants such as rice, cotton, rose etc.Read moreRead less
Understanding The Sources Of Campylobacter In Australia
Funder
National Health and Medical Research Council
Funding Amount
$546,720.00
Summary
Campylobacter is a key cause of foodborne disease in Australia, with rates of illness amongst the highest in the world. Our project brings together academic, government and industry partners to harness new genetic techniques to better identify sources and risk factors for Campylobacter infection. The project will assist health agencies to include genomics in public health, with findings directly informing government policies and industry practices to minimise disease caused by Campylobacter.
Mechanism design for next generation random access wireless protocols. Australia is well placed to take the lead in replacing carbon-intensive travel by teleconferencing, because of its isolation and geographic dispersion. Because these large distances introduce inevitable delays, it is important that the network itself add as little delay as possible for such real-time services. Our novel and practical resource allocation scheme will enable Australians (including Australian industries and rural ....Mechanism design for next generation random access wireless protocols. Australia is well placed to take the lead in replacing carbon-intensive travel by teleconferencing, because of its isolation and geographic dispersion. Because these large distances introduce inevitable delays, it is important that the network itself add as little delay as possible for such real-time services. Our novel and practical resource allocation scheme will enable Australians (including Australian industries and rural communities) to receive better service at lower cost. This project will put Australia on the international stage as a leading contributor to wireless Internet technology. We will provide training for PhD students and postdoctoral fellows in this important area.Read moreRead less
Biofocussed Prostate Cancer RadioTherapy (BiRT): A Personalised Approach To Delivering The Right Dose To The Right Place
Funder
National Health and Medical Research Council
Funding Amount
$753,565.00
Summary
We propose a new approach to treating prostate cancer with radiotherapy to move from the standard whole prostate treatment to a personalised treatment that varies radiation intensity throughout the prostate. We will mathematically combine features that influence radiotherapy effect from advanced imaging, clinical and biopsy information. This model will map out the radiotherapy dose required at each part of the prostate, to maximise killing of the cancer whilst minimising harm to normal tissue
Fellowship Application, Ed Stanley: Pluripotent Stem Cells & Medical Research
Funder
National Health and Medical Research Council
Funding Amount
$638,517.00
Summary
Human Pluripotent Stem Cells are immortal cells that have the ability to turn into any of the cell types found in the body. This means that it is now possible to generate a variety of human cell types in the laboratory, to study how they work, and to find out what goes wrong in different diseases. In this context, the overall aim of my research is to develop pluripotent stem cells for the study of human disease and generate tools that will enable others to use these cells in their own research.
Data Fusion Techniques for Electro-Mechanical Braking Systems. The main focus of this project is to develop data fusion techniques for clamp force estimation and optimum utilisation of redundant information in a brake-by-wire system. Efficient integration of redundant information in an EMB system is expected to significantly improve the reliability and fault tolerance of such systems. The need for costly and complicated clamp force measurement sensors in electric callipers will also be eliminate ....Data Fusion Techniques for Electro-Mechanical Braking Systems. The main focus of this project is to develop data fusion techniques for clamp force estimation and optimum utilisation of redundant information in a brake-by-wire system. Efficient integration of redundant information in an EMB system is expected to significantly improve the reliability and fault tolerance of such systems. The need for costly and complicated clamp force measurement sensors in electric callipers will also be eliminated by accurate estimation of the clamp force signal, through fusion of more readily available measurements. Development of the proposed data fusion techniques influences the design of future EMBs and enhances the functionality of existing brake-by-wire systems.Read moreRead less
The estimation of genotype-phenotype relationships from family data and of animal abundance from capture-recapture data with frequent capture occasions: A semiparametric approach. Semiparametric statistical methods allow researchers to only model those features of their data that are of interest, but still allow standard statistical inferences to be made about these features. The aim here is to develop non standard applications of semiparametric statistical methods in the estimation of genotype ....The estimation of genotype-phenotype relationships from family data and of animal abundance from capture-recapture data with frequent capture occasions: A semiparametric approach. Semiparametric statistical methods allow researchers to only model those features of their data that are of interest, but still allow standard statistical inferences to be made about these features. The aim here is to develop non standard applications of semiparametric statistical methods in the estimation of genotype-phenotype relationships from family data and the estimation of animal abundance from capture-recapture data. The methods will be applied to real data and their theoretical properties developed. The practical significance of the project is the flexible new statistical methods that will become available to researchers. The theoretical significance will be the insights into semiparametric methods gained by developing these nonstandard applications. The expected outcomes are the new statistical procedures and the resulting theoretical insights into semiparametric statistics.Read moreRead less
Eliminating Hepatitis C Transmission By Enhancing Hepatitis C Care And Treatment In Primary Health Care Settings.
Funder
National Health and Medical Research Council
Funding Amount
$1,221,831.00
Summary
In developed countries, people who inject drugs (PWID) are the group at greatest risk of hepatitis C (HCV) infection but few PWID receive HCV treatment. With the advent of highly effective non-interferon based treatments HCV elimination, although ambitious, is now being seriously considered globally. This partnership grant will explore the feasibility of eliminating HCV transmission by enhancing HCV care and treatment for PWID in primary health care settings.
Centre For Research Excellence In Total Joint Replacement OPtimising OUtcomes, Equity, Cost Effectiveness And Patient Selection (OPUS)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Joint replacement surgery is one of the most successful surgeries performed in Australia and globally. With an ageing population, demand for this procedure will increase dramatically, placing burden on a constrained health system. This Centre targets the journey of patients undergoing joint replacement surgery, seeking to optimise patient safety and outcomes, in addition to improving efficiencies and equitablity of this important surgical procedure.
Planetary Pulsations: Exploring Links between Superplumes, Supercontinents, and Superchrons with 3-D Spherical Mantle Convection Models. This project advances the tools and knowledge base regarding historic motions of tectonic plates (including the Australian continent). This furthers understanding of the current and past state of stress in the Earth's surface, ultimately improving ways of characterizing earthquake hazard and mineral exploration. This project also benefits researchers interpre ....Planetary Pulsations: Exploring Links between Superplumes, Supercontinents, and Superchrons with 3-D Spherical Mantle Convection Models. This project advances the tools and knowledge base regarding historic motions of tectonic plates (including the Australian continent). This furthers understanding of the current and past state of stress in the Earth's surface, ultimately improving ways of characterizing earthquake hazard and mineral exploration. This project also benefits researchers interpreting the climate record as two processes which effected the ancient climate are investigated: major outbursts of greenhouse gases during periods of major volcanism and the reorientation of the planet with respect to its spin axis. The results are obtained with these computer simulations highlight Australia's emerging strength in supercomputing on the international scene.
Read moreRead less