Human Epilepsy: Understanding Biology To Improve Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$16,657,948.00
Summary
Our team of neurologists, molecular geneticists, physiologists and brain imaging specialists and leads the world in the discovery of the genetic causes of epilepsy. Through this work we will identify genes underlying epilepsy and study how genetic variations result in the development of seizures. Advanced brain imaging will be used to understand the effects of genetic variation on brain structure and function. This study may lead to new diagnostic methods and treatments for epilepsy.
Musculoskeletal Pain And Disability: Improving Outcomes Through Conservative Interventions
Funder
National Health and Medical Research Council
Funding Amount
$8,549,204.00
Summary
Musculoskeletal conditions (particularly back pain and osteoarthritis) are highly prevalent and have a major impact on health and well being of Australians. This Program aims to resolve the major priorities in the field: optimal methods to target the right treatment to the right person at the right time through our unique strategy to understand mechanisms and identify patient subgroups, and establish optimal methods to overcome barriers to translation of research to policy and practice.
Clinical, Public Health And Policy Interventions To Combat Cardiovascular Diseases
Funder
National Health and Medical Research Council
Funding Amount
$24,025,090.00
Summary
This program will generate and translate evidence from high-quality research designed to inform the decisions of health care providers and policy makers about best strategies for the prevention and treatment of cardiometabolic conditions. The program, with both domestic and global relevance, will address a spectrum of issues, with translational outcomes for clinical research.
This proposal is for a team of researchers and clinicians to explore the molecular control of the lymphatic vasculature. This network of lymphatic vessels, located in organs throughout the body, is critical for regulation of tissue fluid and immune function. It will identify new molecular pathways controlling lymphatic vessels and their interactions with other cells in the body and identify new diagnostic approaches and molecular targets for medicines to treat human diseases including cancer.