Assessment Of The Utility Of Genomics For Sydney Rock Oyster Breeding
Funder
Fisheries Research and Development Corporation
Funding Amount
$620,000.00
Summary
Genomics is routinely used across many livestock and plant breeding industries. It is now practical, within certain considerations, to consider applying genomic selection to aquaculture breeding programs due to significant cost reductions in the last decade. Its use in aquaculture breeding programs is increasing and genomics has already been researched for oyster breeding by USC (Vu et al. 2021a; Vu et al. 2021b).
Genomic selection has the potential to reduce the cost of estimating bre ....Genomics is routinely used across many livestock and plant breeding industries. It is now practical, within certain considerations, to consider applying genomic selection to aquaculture breeding programs due to significant cost reductions in the last decade. Its use in aquaculture breeding programs is increasing and genomics has already been researched for oyster breeding by USC (Vu et al. 2021a; Vu et al. 2021b).
Genomic selection has the potential to reduce the cost of estimating breeding values, which presently is a costly and challenging exercise with SROs and also may potentially increase genetic progress and selection accuracy for the SRO BP. The research proposed in this application will evaluate if it is possible to increase genetic progress for the productivity traits of QX disease resistance and growth as well as the product quality trait of meat condition. Increased QX survival and growth are particularly important traits for the SRO industry at this current time due to Port Stephens, the second largest SRO producing estuary in NSW, reeling from the impact of QX disease outbreaks. Climate change resilience is a new trait being investigated for incorporation into the breeding program for industry to respond to this threat. We would also like to assess whether genomics can provide a pathway to increase selection for resilience.
This project has been developed in line with the Oysters Australia Strategic Plan 2020 and the FRDC R&D Plan 2020-2025. The outcomes from this project will assess the feasibility of increasing selection accuracy for traits that improve productivity (growth and meat condition) as well as reduce impacts caused by QX disease and climate change through breeding for resilience. The outcomes will assess the possibility to improve genetic selections for multiple traits such that oysters can be selected on their ability to adapt to new climate conditions, survive QX disease whilst having faster growth and better meat condition. Additionally, this project will build new knowledge skills and networks through a NSW DPI, The University of the Sunshine Coast and The University of New South Wales alliance as well as create post-doctoral study opportunities. These meet the goals in Program 1, 2 and 3 outlined in the 2020-2025 Oysters Australia Strategic Plan.
With respect to the FRDC R&D Plan 2020-2025, this project will build capacity and create knowledge through developing skills and networks between NSW DPI, The University of the Sunshine Coast and The University of NSW to breed oysters that offer oyster businesses greater profitability, reduced risk and that can adapt to changing environments.
This project will explore alternative methods to what is presently used for SRO breeding to assess feasibility of genomic selection and what might be required today to move towards genomic selection in the future. This project will start compiling a reference library for SROs that can be used in the future and promote innovation in SRO breeding to integrate the technology developed from this project. Moreover, costs associated with genomic selection are reducing which increases the value proposition for incorporation into the future. The ultimate success and transfer of outcomes from this project to end user beneficiaries will be through incorporation of these new technologies into the SRO breeding program. Objectives: 1. Collect tissue samples using non-lethal methods and tagging to identify oysters 2. Sequence the whole genomes of selected individuals at high read depth, which will serve as the genotype resource for the project 3. Identify the associations between genotypes and phenotypes and compile a list of genetic markers and the genes associated with QX survival, whole weight and meat condition to then use modelling (for genomic predictions) to give individuals breeding values Read moreRead less
Bringing The Iconic Australian Herring (Arripis Georgianus) To The Food Service And Retail Market – Phase One
Funder
Fisheries Research and Development Corporation
Funding Amount
$70,000.00
Summary
This Australian Herring FRDC project is a strategic initiative to promote the recently recovered commercial Herring fishery. Blueshift and the commercial sector – represented by Fins Seafood and Albany Seafoods, are strong supporters of benefiting the commercial herring industry through increased demand and production. Fins Seafood focus on locally sourced seafood and have the experience and are passionate in this area, solidifying their undeniable importance to be a part of this project. This Australian Herring FRDC project is a strategic initiative to promote the recently recovered commercial Herring fishery. Blueshift and the commercial sector – represented by Fins Seafood and Albany Seafoods, are strong supporters of benefiting the commercial herring industry through increased demand and production. Fins Seafood focus on locally sourced seafood and have the experience and are passionate in this area, solidifying their undeniable importance to be a part of this project.
The project is needed to reaffirm the presence Australian Herring within the seafood market as commercial landings increase over the coming decade. If Australian Herring is successfully marketed, there is a potential for success within the local domestic market and potentially for export, if export approval is granted by the Australian Government. Furthermore, it is designed to address these challenges by providing investment for research, development, and extension initiatives aimed at improving the sustainability and profitability of the Australian Herring fishery. If successful, this proposal aims to obtain an accurate sense of the market appetite and consumer demand, as well as the potential to value-add by using local seafood processors.
Effective marketing through potential branding, introduction of new products and developing the presence of Australian Herring locally will be beneficial to industry and consumers. Furthermore, successful utilisation of all associated fish waste will bring more value and benefit to industry.
Objectives: 1. Identification of the current market demand and future demand forecasts for Australian Herring. 2. Transition Australian Herring from bait to the higher-value human consumption market. 3. Development of three value-add Australian Herring products. 4. Identification of methods of full utilisation of Australian Herring waste products. 5. Development of effective market strategies to introduce value-add Australian Herring products to the retail market. Read moreRead less
Bringing The Iconic Australian Herring (Arripis Georgianus) To The Food Service And Retail Market – Phase Two
Funder
Fisheries Research and Development Corporation
Funding Amount
$169,000.00
Summary
The WA commercial herring fishery recently reopened following improvements in the stocks sustainability assessments. The product has traditionally been predominantly used for bait. This project, in partnership with herring producers, processors and retailers, will commence with a historical and current status review and consultation to better understand barriers and opportunities for commercial success of herring products for human consumption. Review of the commercial success or otherwise of ....The WA commercial herring fishery recently reopened following improvements in the stocks sustainability assessments. The product has traditionally been predominantly used for bait. This project, in partnership with herring producers, processors and retailers, will commence with a historical and current status review and consultation to better understand barriers and opportunities for commercial success of herring products for human consumption. Review of the commercial success or otherwise of similar underutilised species (such as Australian Salmon) will also be included. From this review, it is intended to identify, develop and implement three new retail and/or food service opportunities for herring for human consumption. Such opportunities, informed by the review, may be new product based (incorporating alternate processing strategies and/or 100% utilisation principles) or focussed on new marketing strategies. Evaluation for future commercial success will be economic, logistical and technical and will use evaluation metrics developed in previous projects. An enhanced use of herring for human consumption may not only increase profitability but may also lead to greater stock access for fishers. A framework for improving commercial success of such underutilised species research projects(reported in FRDC 2017/185) may be further extended by the study. Objectives: 1. Identify options to value add and (where possible) fully utilise the Australia Herring through the human consumption market 2. Investigate, implement and evaluate up to three human consumption market opportunities for Australian Herring-based products 3. Document and extend the developed supply chain framework methodology to get proposed new products to the market and explain how it can be replicable for other similar underutilised / lesser-known species Read moreRead less
Researching, Trialling And Evaluating A Market Driven Approach To Commercialising A Range Extended Marine Species - Tasmanian Wild Sea Urchin (Longspined Sea Urchin)
Funder
Fisheries Research and Development Corporation
Funding Amount
$560,000.00
Summary
Commercial in confidence. To know more about this project please contact FRDC. Objectives: Commercial in confidence
Precision Epigenetics: Targeting The Epigenome To Treat Disease
Funder
National Health and Medical Research Council
Funding Amount
$1,940,576.00
Summary
Epigenetic marks are changes made to the DNA that allow genes to be switched off in some cells and switched on in others. These marks are critical to normal development and often go wrong in disease. We aim to find genes that add epigenetic marks to the DNA and understand how they co-operate at the molecular level to switch genes off. Our focus is on one such gene, SMCHD1. We are developing new drugs against SMCHD1 to treat incurable neurodevelopmental disorder PWS and muscular dystrophy FSHD.
Overcoming The Barriers To Treatment Of Multi-drug Resistant Gram-negative Bloodstream Infections In Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$447,603.00
Summary
There is a critical need to develop new treatments for children with antibiotic resistant infections. The most important bacteria causing resistant infections are known as Gram-negative bacteria. Doctors treating children with resistant Gram-negative infections are faced with few antibiotic options. This project will discover the most important resistant infections in Australian children, and trial a new antibiotic to help doctors to use it in the right children and at the right dose.
Optimizing Immunotherapy Treatment For Breast Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$1,938,014.00
Summary
The first steps in introducing immunotherapy for breast cancer patients have been taken in 2019. However, there is much work to do optimize immunotherapy for all breast cancer patients. My research, involving both lab and clinical trials, will develop new treatment strategies and identify new biomarkers to distinguish responders and non-responders. This will allow individualised selection of patients for evaluation of different immunotherapy approaches, with the aim of improving their survival.