Developmental Schizotypy In The General Population: Early Risk Factors And Predictive Utility.
Funder
National Health and Medical Research Council
Funding Amount
$830,952.00
Summary
This study will determine early childhood risk factors for psychosis-proneness in children aged 11 years, and emerging signs and symptoms of mental health disorders of these children, using population data from the NSW Child Development Study. Determining risk for psychosis as early as possible in the life course will enable the provision of preventative interventions to children at critical points in development.
Achieving Better Mental Health For Maltreated Children: Translating Population Data Into Policy
Funder
National Health and Medical Research Council
Funding Amount
$522,706.00
Summary
This project uses linked population data to determine (a) the earliest indicators of risk of harm, and (b) mental health outcomes and health-care costs associated with children receiving child protection services, in partnership with the NSW department of Family and Community Services. The findings will ensure timely and effective responses to the most vulnerable children to mitigate adverse mental health and other outcomes associated with early life adversity.
Identifying New Targets For Primary School Mental Health Interventions Using Population Data
Funder
National Health and Medical Research Council
Funding Amount
$798,882.00
Summary
This project assesses the mental health and well-being of ~87,000 children aged 10 years in New South Wales, and links this information (anonymously) with data on school-based mental health interventions, and data on health, education, and welfare collected from birth. We will identify factors that promote mental health and reduce ill-health. We hope to improve child health by developing new ways to detect early vulnerability for ill-health, and by identifying new health promotion opportunities.
A Population-based Record Linkage Study Of The Impact Of Chlamydia Infection On Reproductive Health In Women
Funder
National Health and Medical Research Council
Funding Amount
$405,114.00
Summary
Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Au ....Chlamydia is the most commonly notified infection in young Australian women and reports of cases are increasing. While chlamydia is thought to result in infertility and ectopic pregnancy in later life, the evidence for this is limited. This will be the largest, most comprehensive study in the world to determine the risk of infertility and ectopic pregnancy following chlamydia infection. The results will provide vital information to more cost-effectively plan strategies to control chlamydia in Australia.Read moreRead less
Post-market Surveillance Of Medicine-related Adverse Events
Funder
National Health and Medical Research Council
Funding Amount
$99,248.00
Summary
Observational studies using administrative data are an important complement to spontaneous reporting systems for detecting medicine-related adverse events after they go to market, as they reflect real-world use of medicines; yet, they require rigorous methodological approaches to avoid bias. This project will review the existing methodologies for detecting adverse events in administrative data and apply them to Australian data.
HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Sydney Epilepsy Incidence Study To Measure Illness Consequences (SEISMIC)
Funder
National Health and Medical Research Council
Funding Amount
$694,067.00
Summary
Epilepsy is common, costly and neglected. This study is a prospective cohort study of newly diagnosed cases of epilepsy and aims to fill clinical, psychosocial and economic knowledge gaps in epilepsy. The network will use this new evidence for policy recommendations and strategic plans, for health systems and guidelines to improve efficiency and care and to enlighten community-based support programs, education, driving and workplace legislation. This study was developed by a health service, Epil ....Epilepsy is common, costly and neglected. This study is a prospective cohort study of newly diagnosed cases of epilepsy and aims to fill clinical, psychosocial and economic knowledge gaps in epilepsy. The network will use this new evidence for policy recommendations and strategic plans, for health systems and guidelines to improve efficiency and care and to enlighten community-based support programs, education, driving and workplace legislation. This study was developed by a health service, Epilepsy Action, Epilepsy Society of Australia and the George Institute.Read moreRead less
Literary Self-Awareness and Parental Love: Challenging Alterity in Contemporary Medieval Studies. Did medieval women write about themselves as gendered individuals? Did medieval parents love their children? Despite both popular and academic opinion to the contrary, this project aims to demonstrate that these propositions are true. By studying the self-aware writings of Latin-literate medieval women and medieval parent-child advice-texts, this project aims to challenge the alterity, or otherness, ....Literary Self-Awareness and Parental Love: Challenging Alterity in Contemporary Medieval Studies. Did medieval women write about themselves as gendered individuals? Did medieval parents love their children? Despite both popular and academic opinion to the contrary, this project aims to demonstrate that these propositions are true. By studying the self-aware writings of Latin-literate medieval women and medieval parent-child advice-texts, this project aims to challenge the alterity, or otherness, of the Middle Ages, a concept which suggests that medieval people are fundamentally unlike us. In doing so, it questions the significance of alterity in the construction and practices of contemporary Medieval Studies and offers insights into possible new methodologies for the discipline.Read moreRead less
Combating Escalating Harms Associated With Pharmaceutical Opioid Use
Funder
National Health and Medical Research Council
Funding Amount
$925,767.00
Summary
Increases in opioid use have been accompanied by increased opioid harms. But there is a lack of population-level evidence about drivers of long-term prescribed opioid use, dependence, overdose and other harms. Using linked data, we will fill these gaps using a cohort of all people in NSW prescribed opioids since 2002, linked to datasets containing information on health, social and health service utilisation, that will permit a comprehensive assessment of the risks of all prescribed opioids.
Textual Ontogeny and the Understanding of Modernist Texts: A Case Study of Samuel Beckett's Novel, Watt. This research develops smart technology use: by creating a new method of literary editing that is best able to extend the capabilities of electronic text, this project enhances the understanding of modernist literature and the ability to use technology in innovative ways in the humanities. New ways to organise and edit complex networks of data and documentation (in this case extensive archiva ....Textual Ontogeny and the Understanding of Modernist Texts: A Case Study of Samuel Beckett's Novel, Watt. This research develops smart technology use: by creating a new method of literary editing that is best able to extend the capabilities of electronic text, this project enhances the understanding of modernist literature and the ability to use technology in innovative ways in the humanities. New ways to organise and edit complex networks of data and documentation (in this case extensive archival and published material) will be transferable to a wide variety of non-literary applications.Read moreRead less