HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Using Total Population Data To Describe The Characteristics Of Respiratory Infections In Order To Predict Future Epidemics And Recommend Vaccination Strategies For Western Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$294,892.00
Summary
Respiratory infections are a major reason for children to go to hospital. I am an epidemiologist and I will be using previously collected and linked laboratory and hospital data from Western Australian children to better understand how these infections flow through the population over different seasons. I will then be able to predict future epidemics of respiratory infections and how different vaccine programs might have an impact in reducing how many children are affected by these infections.
Vaccination Timeliness In Aboriginal And Non-Aboriginal Infants: Risk Factors For Delayed Vaccination And Impact On Disease Burden—a Record Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$538,183.00
Summary
Vaccination has had a significant impact, but preventable infections continue to occur, perhaps due to delayed uptake of scheduled doses. For the first time, we will link vaccination and other health records to: provide accurate estimates of the impact of vaccination; identify reasons for delayed vaccination; and quantify the expected reduction in disease burden if vaccination timeliness was improved. The study will help determine who would benefit most from efforts to improve timeliness.
Child Health And Development: A South Australian Data Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$283,934.00
Summary
Children’s healthy development is important for their readiness to learn, academic achievement at school, and for their future health and economic capability. This study links whole-of-population administrative data from nine different government sources, and data collected as part of a natural experiment evaluating the effects of the South Australian Family Home Visiting program to inform policy and service delivery in child health and development in South Australia.
Improving Global Tuberculosis Control With The AuTuMN Platform
Funder
National Health and Medical Research Council
Funding Amount
$655,059.00
Summary
Tuberculosis (TB) is the world’s leading infectious killer, with the failure of global control responsible for the vast majority of Australia’s cases. Using our robustly developed software platform, we have performed several country-level studies to predict the future burden of disease and compare the impact of alternative responses to controlling the epidemic. In this project, we will extend our platform to perform simulations at the global level and answer key questions in TB control.
A Community-based Cluster Randomized Controlled Trial In Rural Bangladesh To Evaluate The Impact Of The Use Of Iron/folic Acid Supplements Early In Pregnancy On The Risk Of Neonatal MortalityBACKGROUND An Effective Program Of Antenatal Iron/folic Ac
Funder
National Health and Medical Research Council
Funding Amount
$2,564,922.00
Summary
This community-based trial in rural Bangladesh will determine if iron/folic acid supplementation commencing in the first trimester of pregnancy significantly reduces newborn deaths, and whether this approach is cost-effective. This trial has the potential to inform international public health policy about the importance of starting antenatal iron/folic acid supplementation early to improve neonatal survival, and to help countries reach their child survival Millennium Development Goal
Risk Of Hepatitis C Reinfection Among People With Current Injecting Drug Use Following Successful HCV Treatment
Funder
National Health and Medical Research Council
Funding Amount
$2,245,228.00
Summary
In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs ....In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs.Read moreRead less
Evolutionary models and bioinformatic analyses of genetic variation in pathogens. The benefits of this project are better preparedness for the ever-present threat of infectious disease spread and the stimulation of bioinformatic research in Australia. Epidemics such as the Influenza Pandemic of 1918, which killed over 20 million people, highlight the need to understand and track pathogens that can potentially cause such devastation. Along with the development of molecular technologies, it is imp ....Evolutionary models and bioinformatic analyses of genetic variation in pathogens. The benefits of this project are better preparedness for the ever-present threat of infectious disease spread and the stimulation of bioinformatic research in Australia. Epidemics such as the Influenza Pandemic of 1918, which killed over 20 million people, highlight the need to understand and track pathogens that can potentially cause such devastation. Along with the development of molecular technologies, it is important to maintain active creation of analytical methods that appropriately apply to growing databases. These include methods to understand genetic variation in pathogens. This project will help to keep Australia at the forefront of research in theoretical biology.Read moreRead less
Humanitarian migrants' settlement in Australia: A longitudinal study. Current evidence suggests that humanitarian migrants settle less successfully than other immigrants both economically and socially. This project aims to examine the causal mechanisms and pathways to economic, sociocultural and political settlement outcomes of humanitarian migrants to Australia. This project expects to generate new knowledge in the area of humanitarian migrants’ settlement by using nationally representative dat ....Humanitarian migrants' settlement in Australia: A longitudinal study. Current evidence suggests that humanitarian migrants settle less successfully than other immigrants both economically and socially. This project aims to examine the causal mechanisms and pathways to economic, sociocultural and political settlement outcomes of humanitarian migrants to Australia. This project expects to generate new knowledge in the area of humanitarian migrants’ settlement by using nationally representative data and cutting-edge longitudinal techniques.Expected outcomes include enhanced research capacity in causal methods, interdisciplinary and institutional collaborations, and evidence-based social policy for humanitarian migrants, significantly benefitting humanitarian migrants directly and society more broadly. Read moreRead less