Making Fetal Alcohol Spectrum Disorders History In The Pilbara: An Evidence-based Prevention Intervention
Funder
National Health and Medical Research Council
Funding Amount
$1,703,824.00
Summary
This project creates and evaluates a community-oriented Fetal Alcohol Spectrum Disorder prevention program. Based on an internationally recognised model, the program will be delivered through the Pilbara’s Aboriginal Health Organisations and WA Country Health Service and will assist Aboriginal women, partners, community and health providers. Program success will result in a reduction in alcohol use during pregnancy, and increased community and health providers’ knowledge, attitudes and practice.
Supporting Knowledge Translation In Aboriginal And Torres Strait Islander Primary Health Care: A Developmental Evaluation Of A Stakeholder Engagement Process To Support Use Of Evidence In Systems And Policy Change
Funder
National Health and Medical Research Council
Funding Amount
$66,784.00
Summary
The research uses a developmental evaluation approach and mixed methods to evaluate a dissemination activity that engages stakeholders in Aboriginal and Torres Strait Islander primary health care in using aggregated quality improvement data to identify and address evidence-to-practice gaps in healthcare. Evaluation processes are being used to refine dissemination processes and materials. Findings will also offer insights about using developmental evaluation approaches in knowledge translation.
Health System Performance And Outcomes For Indigenous Australians With Cancer: A National Study.
Funder
National Health and Medical Research Council
Funding Amount
$412,354.00
Summary
Cancer has only recently been recognised as a significant Indigenous health issue, partly because no national information has been available on the impact of cancer on Indigenous people or on health system performance for Indigenous cancer patients. Recent research in the Northern Territory has demonstrated large deficiencies in diagnosis, treatment and survival for Indigenous compared to other cancer patients. Despite imperfect data on Indigenous status, important information can be obtained ab ....Cancer has only recently been recognised as a significant Indigenous health issue, partly because no national information has been available on the impact of cancer on Indigenous people or on health system performance for Indigenous cancer patients. Recent research in the Northern Territory has demonstrated large deficiencies in diagnosis, treatment and survival for Indigenous compared to other cancer patients. Despite imperfect data on Indigenous status, important information can be obtained about health system performance for Indigenous Australians from national administrative databases and registers. This project will assess health system performance and outcome for Indigenous people with cancer at a national level for the first time. It will compare Indigenous with non-Indigenous cancer survival rates for Australia as a whole, including regional (urban-rural-remote) variations and time trends. For those states where data on stage at diagnosis and hospital treatment are available, it will also investigate the performance of diagnostic and treatment services for Indigenous cancer patients by comparing their stage at diagnosis and surgical treatment with that for non-Indigenous patients. Time trends for each of these issues will be examined using data from those states with data of adequate quality and consistency over the past 10-15 years. This project will provide the methodological basis for regular reporting of Indigenous cancer survival and related statistics in the national cancer reporting system and demonstrate that national monitoring of the acute care system for Indigenous people is possible for other conditions. The results of this research will directly inform acute care policy and practice for Indigenous people with cancer (particularly the relative need for improvement in primary health or acute care services), and have implications for the performance of the acute care system system more generally for Indigenous Australians.Read moreRead less
ARDAC (Antecedents Of Renal Disease In Aboriginal Children) Follow-up Study
Funder
National Health and Medical Research Council
Funding Amount
$298,268.00
Summary
Indigenous people world-wide have higher rates of kidney failure than non-Indigenous people. Aboriginal Australians have the highest rates of kidney failure in the world, especially in those living in remote areas. The reasons for this are complex, and include well-known environmental risk factors that contribute to many diseases in Aboriginal people - socio-economic disadvantage, higher rates of infection, smoking, alcohol abuse and poor nutrition. There are also biological risk factors more sp ....Indigenous people world-wide have higher rates of kidney failure than non-Indigenous people. Aboriginal Australians have the highest rates of kidney failure in the world, especially in those living in remote areas. The reasons for this are complex, and include well-known environmental risk factors that contribute to many diseases in Aboriginal people - socio-economic disadvantage, higher rates of infection, smoking, alcohol abuse and poor nutrition. There are also biological risk factors more specific to kidney disease such as low birth weight babies, reduced kidney volume, female sex, family history of kidney disease, genetic influences, over and under-nutrition and high blood pressure. Many of these risks may take effect in childhood, resulting in silent kidney damage that may become chronic in adulthood when diabetes and other influences take effect. In order to clarify the degree of risk early influences have on Aboriginal kidney disease before adult confounders complicate the picture, a unique study of early signs of kidney disease in outwardly healthy Aboriginal children was planned. These school children come from different locations across NSW, and have a non-Aboriginal comparator group. The first primary aims are complete: To determine: 1. Rates of blood and protein in the urine, and high blood pressure in Aboriginal as compared to non-Aboriginal children. These are the early markers, or antecedents of kidney disease; 2. If these antecedents differ over urban, coastal, rural and remote regions, and socio-economic areas; 3. Any association between antecedents and other risk factors such as age, gender, birth weight and growth; Secondary aims are currently underway: To determine: 1. The natural history of these antecedents of kidney disease by following these children for a further 4 years; 2. Which risk factors are more likely in children with persisting antecedents -ie the children more likely to develop serious kidney disease.Read moreRead less
Aboriginal Australians are diagnosed with chronic kidney disease at approximately 10 times the rate of non-Aboriginal Australians. Since 2002, the ARDAC Study has examined the early markers of kidney and heart disease in Aboriginal and non-Aboriginal children and adolescents. The study aims to determine if the increased risk of chronic kidney and heart disease seen in Aboriginal adults begins during adolescence and young adulthood as an increased prevalence of chronic disease risk factors.
A Prospective Study Of The Aetiology, Associations, Clinical Features And Outcomes Of Community-acquired Pneumonia In Children And Adults In Tropical Australia
Funder
National Health and Medical Research Council
Funding Amount
$106,937.00
Summary
Pneumonia is common in Australia and often requires hospital admission. The germs that cause pneumonia in tropical Australia are less well known than southern Australia and likely to be different. This study will identify which germs cause pneumonia in people in tropical Australia and will identify which people become more unwell. I aim to identify the best antibiotics to use, the differences between children and adults, Indigenous and non-Indigenous people and people living in different areas.
A Multi-centre Double-blind RCT On Community-acquired Pneumonia In Indigenous Children And A Developing Country: Improving Clinical Outcomes And Identifying Systemic Biomarkers
Funder
National Health and Medical Research Council
Funding Amount
$2,167,560.00
Summary
Young children of Indigenous communities and developing countries are often hospitalised for pneumonia and have high risk of subsequent chronic disease. Our international study will determine if a longer duration of antibiotics (compared to shorter duration) improves the short and long term clinical outcomes of children hospitalised for pneumonia. We will look for unique markers that may predict those who will develop chronic lung disease. Our study will influence future guidelines on pneumonia.
A Centre For Research Excellence: Building Indigenous Research Capacity To Find Solutions To Alcohol Problems
Funder
National Health and Medical Research Council
Funding Amount
$2,495,984.00
Summary
Aboriginal and Torres Strait Islander (Indigenous) Australians are up to eight times as likely to suffer death or illness as a result of alcohol use. Yet there is a critical shortage of Indigenous researchers with expertise in this field. This CRE helps build a strong and continuing network of Indigenous researchers with expertise in treating and preventing alcohol problems. The Centre will generate new knowledge, integrating efforts along the continuum of treatment and prevention.
Povidine-iodine Ear Wash And Oral Cotrimoxazole For Chronic Suppurative Otitis Media In Aboriginal Children: A 2x2 Factorial Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,261,802.00
Summary
Many Aboriginal children in remote communities have severe ear infection. Acute infection with eardrum perforation often leads to long term discharge of pus (chronic suppurative otitis media) usually causing significant hearing loss. This trial will determine the benefit of antiseptic ear washes and a long course of oral antibiotics. We will assess the impact on ear health and hearing.