CONSUMPTION OF NITRATE-RICH VEGETABLES TO REDUCE BLOOD PRESSURE
Funder
National Health and Medical Research Council
Funding Amount
$603,875.00
Summary
Consumption of plant food-rich diets lowers blood pressure. However, the most important components of these diets for blood pressure lowering have not been clearly defined. An intervention study in people with elevated blood pressure will be conducted to determine if increased consumption vegetables results in lower blood pressure, and if focused advice to consume nitrate-rich vegetables (mainly green leafy vegetables) will result in greater benefit on blood pressure.
Making Fetal Alcohol Spectrum Disorders History In The Pilbara: An Evidence-based Prevention Intervention
Funder
National Health and Medical Research Council
Funding Amount
$1,703,824.00
Summary
This project creates and evaluates a community-oriented Fetal Alcohol Spectrum Disorder prevention program. Based on an internationally recognised model, the program will be delivered through the Pilbara’s Aboriginal Health Organisations and WA Country Health Service and will assist Aboriginal women, partners, community and health providers. Program success will result in a reduction in alcohol use during pregnancy, and increased community and health providers’ knowledge, attitudes and practice.
HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Intergenerational Change In Oral Health In Australia
Funder
National Health and Medical Research Council
Funding Amount
$566,827.00
Summary
Australia's population is ageing and Australians are retaining more teeth in later life. It is expected that as life expectancy increases, more years of life are spend in good health, with disease and disability being postponed to later years of life. No evidence is available to test the compression of morbidity hypothesis in relation to oral health in older Australians. This study will test whether these changes have resulted in more years in good oral health in an elderly population.
How Should We Analyse, Synthesize, And Interpret Evidence From Interrupted Time Series Studies? Making The Best Use Of Available Evidence
Funder
National Health and Medical Research Council
Funding Amount
$445,144.00
Summary
Interrupted time series (ITS) studies are frequently used to evaluate whether policy interventions are successful. The findings from these studies are often collated into systematic reviews, which are used to inform healthcare decisions by clinicians, consumers and policy makers. It is not known how the statistical methods, which underpin the findings from ITS studies, perform. This proposal will evaluate the statistical methods and provide guidance on how to analyse and interpret ITS studies.
Risk Of Hepatitis C Reinfection Among People With Current Injecting Drug Use Following Successful HCV Treatment
Funder
National Health and Medical Research Council
Funding Amount
$2,245,228.00
Summary
In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs ....In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs.Read moreRead less
A 10 Year Follow Up Of The Tasmanian Older Adult Cohort (TASOAC).
Funder
National Health and Medical Research Council
Funding Amount
$676,020.00
Summary
The TASOAC study is a population based study looking at the causes and course of osteoarthritis using state of the art techniques. This study will extend follow up to ten years.
Waist Circumference And Absolute Risks Of Chronic Diseases: Evidence For Establishing Waist Circumference Cutoffs For Aboriginal Australians
Funder
National Health and Medical Research Council
Funding Amount
$356,978.00
Summary
The gap in life expectancy between Indigenous and other Australians is unacceptable. Cardiovascular disease, diabetes and kidney failure are major diseases contributing to such a gap. Waist circumference is an important risk marker of those chronic diseases for health promotion and intervention. However, cutoff values for Aboriginal Australians are lacking, which limits its use in this population. In this project, we will provide evidence of multiple sources for establishing appropriate cutoff v ....The gap in life expectancy between Indigenous and other Australians is unacceptable. Cardiovascular disease, diabetes and kidney failure are major diseases contributing to such a gap. Waist circumference is an important risk marker of those chronic diseases for health promotion and intervention. However, cutoff values for Aboriginal Australians are lacking, which limits its use in this population. In this project, we will provide evidence of multiple sources for establishing appropriate cutoff values for Aboriginal people.Read moreRead less
POPULATION-LEVEL RELEVANCE OF RISK FACTORS FOR CANCER
Funder
National Health and Medical Research Council
Funding Amount
$319,692.00
Summary
This research will provide novel up-to-date evidence-based information on the population-level relevance of lifestyle-related risk factors for cancer in Australia, by applying an advanced disease burden measure to established Australian cohort studies. This knowledge on the national cancer burden is essential for targeting cancer interventions for those at highest risk and evaluating their effectiveness.
Trajectories In Brain Structure And Function For Children With And Without ADHD: Associations With Academic, Cognitive, Social, And Mental Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$1,235,951.00
Summary
Attention-Deficit/Hyperactivity Disorder (ADHD) is one of the most common disorders of childhood, affecting 7% of school-age children. This project will use neuroimaging to describe how brain structure and function change across late childhood to early adolescence for children with and without ADHD, and how those changes reflect ADHD symptom severity and functional outcomes (academic, cognitive, social, and mental health).