Developing A Scalable, Woman-centred Model For Cervical Cancer Screening In Vulnerable Women In India
Funder
National Health and Medical Research Council
Funding Amount
$1,330,369.00
Summary
Cervical cancer is a devastating but preventable disease and 1 in 5 cases of cervical cancer in the world occur in India. We will work with women, communities, and health services in two States of India (Tamil Nadu and Mizoram) to design a woman friendly approach to prevent cervical cancer. This project brings together international and Indian experts to overcome current barriers to cervical screening by using a newer, more effective way of screening to reach underserved women and save lives.
Implementation Of A New, Inexpensive And High-throughput Matrix Assisted Laser Desorption / Ionization _ Time Of Flight Mass Spectrometry Test For Superior Detection Of Fragile X Syndrome In Targeted Diagnostics And Newborn Population Screening.
Funder
National Health and Medical Research Council
Funding Amount
$254,175.00
Summary
Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment int ....Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment intervention.Read moreRead less
Using Mathematical Models To Assess The Impact Of Interventions To Reduce Sexually Transmitted Infections In Australia
Funder
National Health and Medical Research Council
Funding Amount
$562,276.00
Summary
Sexually transmitted infections (STIs) are an increasing public health problem in Australia. Australia's recent National Transmissible Infections Strategy identified chlamydia control, STI prevention in gay men and STIs in Aboriginal and Torres Strait Islander communities as priority areas. We propose to develop mathematical models of STI transmission and use these to help understand and identify the most cost-effective interventions to reduce the impact of STIs on Australian populations.
Comparative Effectiveness Of Breast Tomosynthesis And Mammography In Real-world Population Screening: Evidence To Underpin And Improve Breast Cancer Screening
Funder
National Health and Medical Research Council
Funding Amount
$1,851,430.00
Summary
This research addresses key evidence gaps in breast cancer screening by investigating tomosynthesis (3D mammography) versus standard 2D mammography screening to establish the effectiveness of tomosynthesis in Australia and internationally, including impact on cancers not detected at screening that progress clinically. Large-scale studies will be done in real world screening services including a prospective comparative study planned collaboratively with BreastScreen to guide screening policy.
Population Based Genetic Testing For High-risk Breast And Ovarian Cancer Predisposition Genes
Funder
National Health and Medical Research Council
Funding Amount
$1,112,985.00
Summary
Inherited mutations in BRCA1 and BRCA2 confer a very high risk of breast and ovarian cancer. Importantly, once carriers are identified, effective strategies are available that can dramatically reduce the risk of cancer. We will perform genetic testing of a healthy western population to identify breast/ovarian cancer genes before the women develop cancer. Population-based screening could significantly reduce the incidence of these diseases.
ASCAPE: Audio App-delivered Screening For Cognition And Age-related Health In Older Prisoners
Funder
National Health and Medical Research Council
Funding Amount
$844,050.00
Summary
This study aims to develop and test a new, innovative health screening app to examine the health and functioning of older, ageing prisoners in Australia. The app will deliver a range of health and functioning measures via audio, minimising the need for literacy skills and for staff supervision during testing. It is hoped that this app will be easily implemented in prisons in future, to enable better health management for this growing cohort with complex health needs.
Development Of A Blood-based Screening Test For Colorectal Neoplasia; Biomarker Expression In Circulating Tumor Cells And Tumor-derived Microvesicles
Funder
National Health and Medical Research Council
Funding Amount
$513,938.00
Summary
A blood-based test for bowel cancer and the premalignant lesion (i.e. adenomas) has potential to improve several aspects of screening for bowel cancer – improved capacity to detect lesions in well people who do not suspect their presence, avoidance of faecal sampling and fewer false-positive results. There is no reliable simple screening test for adenomas. This study aims at developing a practical blood test based on a device that filters and enriches cells from blood that carry these markers
Re-participation In Screening For Colorectal Cancer: Behavioural Outcomes And Predictors.
Funder
National Health and Medical Research Council
Funding Amount
$687,438.00
Summary
Screening for bowel cancer (CRC) is an important public health initiative. It is most effective when undertaken regularly but there is little research on what personal factors relate to ongoing participation in a screening program. This study will determine the factors associated with ongoing participation in CRC screening and will lead to better screening programs and improved health benefits. This study directly addresses the Cancer Australia priority area re improving screening programs.
Lung Cancer Screening With Low Dose Computed Tomography (LDCT); Exploring Opportunities To Optimise Disease Prevention Across A Range Of Health Outcomes In Australia.
Funder
National Health and Medical Research Council
Funding Amount
$132,743.00
Summary
Lung cancer is the largest cause of cancer related death in the world. Low dose computed tomography (LDCT) is a scan that reduces deaths from lung cancer by detecting early disease. Australia is investigating a national screening program with LDCT. This project evaluates opportunity provided by such a program to develop a personalised approach to screening using information provided by LDCT beyond cancer (e.g. heart and bone disease) and modify risk factors (e.g. physical activity and smoking).
The Role Of A Pharmacist In Sexual Health Services For Women
Funder
National Health and Medical Research Council
Funding Amount
$101,614.00
Summary
The rates of Chlamydia trachomatis in Australia have increased almost six-fold in the last ten years. The social and geographical position of community pharmacies is ideal to increase accessibility to chlamydia screening. This research will investigate into the feasibility of a flexible model of chlamydia screening from community pharmacies for rural, remote and metropolitan areas throughout Australia.