DNA and the missing: ancient DNA and advanced forensic identification. Identifying the remains of missing persons, disaster victims and war dead is of major social and cultural importance and has significant implications for national and international justice systems. This project will apply expertise in analysis of ancient DNA to build capacity and expertise within Australia to identify highly degraded human remains.
The evolution of species traits and spread during biological invasions. Exotic species pose a dire threat to Australia's biodiversity and natural resources due to the speed at which non-indigenous pests spread and the ecological and environmental damage they are capable of causing. The proposed research, on identifying traits associated with the spread of exotic vertebrate species and modelling the reproductive and dispersal parameters among different populations, will provide new knowledge and ....The evolution of species traits and spread during biological invasions. Exotic species pose a dire threat to Australia's biodiversity and natural resources due to the speed at which non-indigenous pests spread and the ecological and environmental damage they are capable of causing. The proposed research, on identifying traits associated with the spread of exotic vertebrate species and modelling the reproductive and dispersal parameters among different populations, will provide new knowledge and aid in developing innovative solutions for arresting the spread of exotic species. The validation of current models of spread will represent a major and timely addition to the national research capability on exotic species, and add substantially to Australia's reputation as a global leader in evolutionary ecology.Read moreRead less
An integrated molecular approach to human evolution. This project aims to use the power of High Throughput Sequencing to investigate a range of genetic mechanisms that facilitate rapid human adaptation to diverse environments. This project expects to create the first ultra-high-quality Aboriginal Australian reference genome using Single Molecule, Real-Time Sequencing, which will expand the known range of human genomic and non-genomic variation. The results should offer the first detailed, long- ....An integrated molecular approach to human evolution. This project aims to use the power of High Throughput Sequencing to investigate a range of genetic mechanisms that facilitate rapid human adaptation to diverse environments. This project expects to create the first ultra-high-quality Aboriginal Australian reference genome using Single Molecule, Real-Time Sequencing, which will expand the known range of human genomic and non-genomic variation. The results should offer the first detailed, long-term reconstruction of the evolutionary history of human adaptability to specific environmental and cultural stressors. Importantly, the translation of the results to biomedical research will shed new light on the origins of modern diseases.Read moreRead less
Stigma and discrimination and their detrimental impact on social inclusion and health and well-being. Experiencing stigma and discrimination harms health and wellbeing, and prevents people from being fully included in society. This project will help us understand how to best reduce stigma and discrimination, and to protect people from their negative effects.
Identifying the genes and population histories that drive rapid adaptive change and speciation. This project will uncover the genetic variation and demographic histories that allow rapid adaptation and speciation in natural populations. It will leverage the powerful framework provided by Indo-Australian sea snakes, and new gene sequencing technologies, to reconstruct the evolutionary histories of genes, populations and species. Using this data, it will address inter-related key questions that ar ....Identifying the genes and population histories that drive rapid adaptive change and speciation. This project will uncover the genetic variation and demographic histories that allow rapid adaptation and speciation in natural populations. It will leverage the powerful framework provided by Indo-Australian sea snakes, and new gene sequencing technologies, to reconstruct the evolutionary histories of genes, populations and species. Using this data, it will address inter-related key questions that are critical to effective biodiversity conservation but have rarely been evaluated in the same taxon. It will address what genetic changes are involved in adaptive shifts and speciation, whether these originate de novo or from pre-existing variation and how gene flow and changes in population size promote or constrain adaptation and speciation.Read moreRead less
Balancing Societies’ Priorities in addressing Emerging National and Global Environmental Challenges. Growing global demands for water, food and energy will continue to intensify land-use conflicts, contribute to carbon emissions, and exacerbate threats to biodiversity. Consumption needs to be balanced with environmental protection. This project aims to frame the issues of food security, rural development, carbon emissions and biodiversity loss from the perspective of ecological and economic theo ....Balancing Societies’ Priorities in addressing Emerging National and Global Environmental Challenges. Growing global demands for water, food and energy will continue to intensify land-use conflicts, contribute to carbon emissions, and exacerbate threats to biodiversity. Consumption needs to be balanced with environmental protection. This project aims to frame the issues of food security, rural development, carbon emissions and biodiversity loss from the perspective of ecological and economic theory. It will use cutting-edge analyses to assess the implications and trade-offs of alternative land-use and development scenarios that reflect key socioeconomic and environmental priorities in Indonesia. Based on these analyses, decision-support tools will be developed to help Indonesian policymakers reconcile these objectives to achieve more sustainable development.Read moreRead less
Evolution, adaptation and resilience of Australian freshwater fishes. This project will integrate comparative ecological genomics (in the wild and in the lab), phenotypic data and spatially-explicit modelling approaches to assess adaptation and vulnerability of aquatic biodiversity to environmental change. It focuses on a family of Australian freshwater fishes that evolved in response to hydrological disturbance and shows contemporary patterns of biodiversity shaped by hydroclimatic variation an ....Evolution, adaptation and resilience of Australian freshwater fishes. This project will integrate comparative ecological genomics (in the wild and in the lab), phenotypic data and spatially-explicit modelling approaches to assess adaptation and vulnerability of aquatic biodiversity to environmental change. It focuses on a family of Australian freshwater fishes that evolved in response to hydrological disturbance and shows contemporary patterns of biodiversity shaped by hydroclimatic variation and anthropogenic pressures. The project expects to disclose a positive correlation between family-wide adaptive capacity and variance in ecological disturbance. This work will address fundamental and novel questions about factors shaping adaptation and resilience along naturally and anthropogenically disturbed ecosystems.Read moreRead less
Discovering the pathways and mechanisms underlying bio-insecticide control of the global migratory pest, diamondback moth, Plutella xylostella. Sustaining crop yield and maintaining food security is a significant worldwide concern. This project aims to strengthen insect pest control strategies and improve bio-insecticide use in agriculture through better understanding of the mode of action of Bacillus thuringiensis (Bt) insecticides. It aims to improve their efficacy and evaluate opportunities t ....Discovering the pathways and mechanisms underlying bio-insecticide control of the global migratory pest, diamondback moth, Plutella xylostella. Sustaining crop yield and maintaining food security is a significant worldwide concern. This project aims to strengthen insect pest control strategies and improve bio-insecticide use in agriculture through better understanding of the mode of action of Bacillus thuringiensis (Bt) insecticides. It aims to improve their efficacy and evaluate opportunities to develop bio-insecticides based on plant saponins. This will assist in determining the risk of insecticide resistant moths migrating to Australia, and within our borders. This project aims to provide opportunities to improve transgenic Bt-crops and Bt-sprays, provide commercial development of new bio-insecticides, and develop optimal control strategies for major Australian migratory pests.Read moreRead less