Improving The Impact Of Perioperative Clinical Trials
Funder
National Health and Medical Research Council
Funding Amount
$494,733.00
Summary
This research focuses on (i) Designing and conducting large multicentre trials in anaesthesia and surgery, (ii) Confirming new patient-centred outcome measures in surgery, such as patient-rated quality of recovery, returning home after surgery, and disability-free survival; and (iii) Innovative trial designs to improve the efficiency (less burden, lower costs) of trials.
Improving Children's Respiratory Health Through Better Evidence And Knowledge
Funder
National Health and Medical Research Council
Funding Amount
$568,892.00
Summary
Prevention and/or early treatment potentially change the child’s life trajectory for lung health as adults. This is particularly important in Aboriginal and Torres Strait Islander children, as respiratory illness is very common with long term consequences. In my fellowship, I will undertake appropriate clinical studies (treatment and preventative) that are most likely to improve lung health outcomes, particularly in conditions relevant in Indigenous children.
Optimising Emergency And Trauma Systems Through Evidence Based Pathways
Funder
National Health and Medical Research Council
Funding Amount
$418,049.00
Summary
Developing systems for emergency and trauma care based on strong evidence and robust data systems is crucial to the acute health sector. Through an extensive, well recognised collaboration of research groups at The Alfred, Monash and the National Trauma Research Institute, we aim to undertake world leading systems development both locally and globally, focusing on prehospital, emergency and trauma clinical care pathways significantly reducing mortality and improving functional outcomes.
Tackling Key Epidemiological And Basic Scientific Research Issues In Prion Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$401,109.00
Summary
Proposed Practitioner Fellowship research will simultaneously include epidemiological and basic scientific projects, emphasising human prion disease. Epidemiological research will involve large-scale studies to clarify genetic factors that influence susceptibility to developing prion disease, as well as clarify whether Alzheimer disease is transmissible, while basic scientific research will include determining the characteristics of the misfolded prion proteins causing neuronal disease.
Prevention And Improved Management Of Paediatric Food Allergy
Funder
National Health and Medical Research Council
Funding Amount
$479,882.00
Summary
There is an urgent need to prevent food allergy and better manage its consequences. My research will identify: causes of food allergy (primary prevention); factors leading to adverse events in food allergic children (secondary prevention); and the role of food allergy in the ‘atopic march’ i.e. progression to other allergic conditions (tertiary prevention). The results of my research will be used to update policy and practice guidelines to change behaviour and improve clinical care.
Implementation Of Highly Effective Therapy For Hepatitis C
Funder
National Health and Medical Research Council
Funding Amount
$569,219.00
Summary
Hepatitis C is a major public health issue in Australia, and globally, with escalating liver disease burden. Highly effective interferon-free HCV regimens will be available from 2016 and have the potential to provide one of the greatest advances in clinical medicine in recent decades. Development of implementation strategies for new HCV therapies, particularly for highly marginalised populations including people who inject drugs and prisoners, is crucial to provide broad public health impact.
This Practitioner Fellowship will support studies that will contribute directly to the efforts to eliminate HCV infection from Australia. The research program aims to reduce transmission of HCV infection by evaluating the best models of care for i) engaging and treating high risk individuals with HCV infection, including people who inject drugs and prisoners, ii) preventing reinfection with HCV, and iii) re-treatment of individuals who fail treatment due to drug resistance.
Childhood Diabetes: Translating Evidence Into Practice
Funder
National Health and Medical Research Council
Funding Amount
$444,014.00
Summary
Type 1 diabetes is one of the most common chronic diseases of childhood. The burden of disease on the individual, their family and the community is enormous. The goal of this fellowship is to utilise evidence-based research to inform health policy and enhance the care of young people with diabetes. The proposal addresses patterns of disease in Australia, environmental triggers for diabetes, and care of the young person with diabetes through implementation of national evidence based clinical care ....Type 1 diabetes is one of the most common chronic diseases of childhood. The burden of disease on the individual, their family and the community is enormous. The goal of this fellowship is to utilise evidence-based research to inform health policy and enhance the care of young people with diabetes. The proposal addresses patterns of disease in Australia, environmental triggers for diabetes, and care of the young person with diabetes through implementation of national evidence based clinical care guidelines for type 1 diabetes.Read moreRead less