Innovative Health Programs To Reduce Inequality In Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
As part of his Senior NHMRC Fellowship, Prof Simon Stewart, a world-renowned health services researcher, will lead an internationally linked team of researchers from a broad range of health disciplines to undertake a program of research designed to improve the lives of those most vulnerable to heart disease and poor health outcomes. His program of research will focus on Indigenous Australians, patients with complex forms of heart disease and urban African communities in economic transition.
The history and mechanisms of modern migration: the British case 1780-1914. The roots of modern migration reside in fundamental agrarian changes which always occur when modern societies embark along the road to industrialisation (such as in Britain in the industrial revolution). These structural changes in the rest of the world are the generic sources of most of Australia's immigrants, past and present. This project investigates the fundamental causes of very long term migration flows which rema ....The history and mechanisms of modern migration: the British case 1780-1914. The roots of modern migration reside in fundamental agrarian changes which always occur when modern societies embark along the road to industrialisation (such as in Britain in the industrial revolution). These structural changes in the rest of the world are the generic sources of most of Australia's immigrants, past and present. This project investigates the fundamental causes of very long term migration flows which remain largely unexplained.Read moreRead less
Diet influences the selective advantage of mitochondrial DNA mutations. This project aims to examine critical mechanisms that affect mitochondrial DNA variation within species. It aims to test the hypothesis that mitochondrial DNA haplotypes have the potential to be under nutritionally induced balancing selection as a consequence of cellular signalling and/or Adenosine triphosphate (ATP) production by mitochondria. Diet can vary both seasonally and geographically and is a key environmental param ....Diet influences the selective advantage of mitochondrial DNA mutations. This project aims to examine critical mechanisms that affect mitochondrial DNA variation within species. It aims to test the hypothesis that mitochondrial DNA haplotypes have the potential to be under nutritionally induced balancing selection as a consequence of cellular signalling and/or Adenosine triphosphate (ATP) production by mitochondria. Diet can vary both seasonally and geographically and is a key environmental parameter that influences the ability of a species to colonise new habitats. The project plans to characterise the functional links between specific mitochondrial DNA haplotypes, mitochondrial functions and organismal traits. The expected outcome is a more precise grasp of the processes influencing genetic variation within and among species, which would inform current issues in ecology and genetics.Read moreRead less
Pathways to health and wellbeing through housing: a new causal understanding of relationships, processes and interventions. Does housing make Australians healthier or less healthy, how can we target housing assistance so that it improves individual health and wellbeing? This research answers these questions, it develops new methods for understanding the complex causal relationship between housing and health, and evidence of how housing can improve health and wellbeing.
Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already i ....Why do only some exotics become invasive? Combining ecological and genomic approaches to address alternative hypotheses in a recent Australian weed. This project will specifically test alternative hypotheses about how weeds become invasive. As invasive weeds affect both agricultural and native ecosystems equally, research on understanding the mechanisms of weed invasion is critical. Outcomes will benefit Australia by allowing better prioritisation of management against exotic plants already in the country by providing predictive tools to estimate likelihood of spread. For formal Pest Risk Analysis by regulators (eg Biosecurity Australia), our project will provide genomic tools by which the potential weediness of a regulated plant can be assessed through genetic screening, and forms part of an international effort to identify 'weedy genes'. Read moreRead less
Zeroing in on food waste: Measuring, understanding and reducing food waste. By developing a socio-culturally aware public education and social marketing programme to reduce food waste behaviours, the proposal addresses the national research priority area of an environmentally sustainable Australia. Reducing food waste by just 10% would save ~$530 million worth of wasted expenditure on food and reduce food waste in landfill by ~300,000 tonnes per annum, thereby reducing the costs associated with ....Zeroing in on food waste: Measuring, understanding and reducing food waste. By developing a socio-culturally aware public education and social marketing programme to reduce food waste behaviours, the proposal addresses the national research priority area of an environmentally sustainable Australia. Reducing food waste by just 10% would save ~$530 million worth of wasted expenditure on food and reduce food waste in landfill by ~300,000 tonnes per annum, thereby reducing the costs associated with disposal and the release of harmful methane gases. The methodology refined by this project to understand food waste will provide the basis for efficient and sustainable food waste reduction strategies and provide an approach that can be generalised to other waste streams with strong socio-cultural determinants.Read moreRead less
The biology and epidemiology of the grapevine canker fungi, Botryosphaeria sp. Decline and dieback of grapevines is becoming an increasing problem for the viticulture industry in NSW. Recently, species of the fungus Botryosphaeria, were isolated from grapevines exhibiting these symptoms. In order to understand the biology and epidemiology of the causal organisms, we aim to; (i) determine species of Botryosphaeria present in NSW vineyards; (ii) determine which species are pathogenic on grapevines ....The biology and epidemiology of the grapevine canker fungi, Botryosphaeria sp. Decline and dieback of grapevines is becoming an increasing problem for the viticulture industry in NSW. Recently, species of the fungus Botryosphaeria, were isolated from grapevines exhibiting these symptoms. In order to understand the biology and epidemiology of the causal organisms, we aim to; (i) determine species of Botryosphaeria present in NSW vineyards; (ii) determine which species are pathogenic on grapevines; (iii) characterise the genetic diversity of strains and; (iv) screen fungicides for the control of these fungi. Information on the species, their biology and pathogenicity on grapevines, will enable the development of appropriate management strategies for its control and may lead to the development of molecular tools to identify species of Botryosphaeria.Read moreRead less
Population structure in the giant Australian cuttlefish - implications for management of a unique eco-tourism and fishery resource in regional Australia. A management strategy for the giant Australian cuttlefish in regional South Australia is required urgently because of potential conflict between ecotourism and fishery sectors. At present, development of a management strategy is stymied by lack of information on stock structure and movements. Analyses of variation in gene frequencies, morphom ....Population structure in the giant Australian cuttlefish - implications for management of a unique eco-tourism and fishery resource in regional Australia. A management strategy for the giant Australian cuttlefish in regional South Australia is required urgently because of potential conflict between ecotourism and fishery sectors. At present, development of a management strategy is stymied by lack of information on stock structure and movements. Analyses of variation in gene frequencies, morphometric and chemical trace element profiles in calcified structures among locations and years will enable the geographic extent of populations or stocks to be determined, including whether natal homing occurs. Such information is critical to sustainable management of the species and design of a marine protected area in the upper Spencer Gulf.Read moreRead less
Domestic Subversions: maternalism and cross-cultural histories. This project will assist in the processes of reconciliation, by fostering a sense of a shared history, and increasing public awareness of the complexity of race relations histories in Australia. It will redress a significant gap in Australian knowledge and literature. Very little is known about the history of Aboriginal domestic workers and their relationships with their white employers in Australia, despite growing awareness of the ....Domestic Subversions: maternalism and cross-cultural histories. This project will assist in the processes of reconciliation, by fostering a sense of a shared history, and increasing public awareness of the complexity of race relations histories in Australia. It will redress a significant gap in Australian knowledge and literature. Very little is known about the history of Aboriginal domestic workers and their relationships with their white employers in Australia, despite growing awareness of the significance of domestic service in Aboriginal child removal policies. The project will also assist in establishing Australian historical scholarship at the forefront of leading international research initiatives in gender, race and colonialism studies. Read moreRead less
Autobiography of a People: Aboriginal Writing in Queensland, 1890s-1930s. As the recent "history wars" confirm, Australians today care deeply about the colonial past, because its legacies are "all around us and within" (as Oodgeroo noted). This project advances knowledge and conceptual understanding in the key areas of colonial race relations, Indigenous self-representation, and Indigenous literacy. Aboriginal autobiography is an especially effective tool for stimulating the empathetic imaginati ....Autobiography of a People: Aboriginal Writing in Queensland, 1890s-1930s. As the recent "history wars" confirm, Australians today care deeply about the colonial past, because its legacies are "all around us and within" (as Oodgeroo noted). This project advances knowledge and conceptual understanding in the key areas of colonial race relations, Indigenous self-representation, and Indigenous literacy. Aboriginal autobiography is an especially effective tool for stimulating the empathetic imagination, and bridging social, temporal and geographical distances between people. This research will strengthen the nation's social fabric by promoting inter-racial understanding, and by adding historical depth to present thinking about contemporary Aboriginal attitudes to literacy.Read moreRead less