Implications Of The Increasing Duration Of Life Spent With Obesity For Population Health
Funder
National Health and Medical Research Council
Funding Amount
$251,830.00
Summary
As the prevalence of obesity at younger ages increases, people are living longer with obesity. We have recently shown that this has an increased risk of mortality and diabetes. In this project we will look at the extent to which an increasing length of time lived with obesity is also associated with increased risks of hypertension, heart disease, cancer, arthritis and disability. We will also look at the effect of this increasing duration on the overall health of Australian adults.
Preventing Mortality In Adults After Release From Prison: Advancing Global Knowledge Through An International, Individual Participant Data Meta-analysis
Funder
National Health and Medical Research Council
Funding Amount
$613,687.00
Summary
Ex-prisoners are at increased risk of death, but not enough is known about the incidence, timing, causes, context or risk factors for preventable death in this population. In this project we have compiled 18 cohorts of ex-prisoners (total number=1,159,290) and will analyse the data to determine exactly which ex-prisoners are at the greatest risk from what, and when. This new knowledge will inform policy changes to reduce the unnecessary loss of life in this vulnerable population.
Biological, Phenotypic And Public Health Costs Of Risk And Protective Pathways To Non-communicable Disease In Children And Adults: The National Longitudinal Study Of Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$1,521,590.00
Summary
Although a late event for most Australians, chronic diseases present a crippling burden for Australia. This project explores their early roots, before overt disease emerges, in 3500 parents and their children in the Longitudinal Study of Australian Children. We will measure how accumulated stress and buffering characteristics play out in the biology of cell ageing and inflammation, in developing heart, lung, kidney and bone health, and in quality of life and health costs to the population.
HIV Treatment As Prevention: A Longitudinal Assessment Of Population Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$783,160.00
Summary
This project is a large-scale evaluation of an HIV strategy known as ‘treatment as prevention’ (TasP). Through routine and repeat HIV testing for gay men and early treatment initiation following diagnosis, TasP aims to reduce HIV community infection rates. Through the establishment of a large cohort of gay men in NSW and Victoria, this study will track HIV testing, treatment and management to assess the real-world efficacy of TasP for reducing HIV infections among this at-risk population.
Is The Incidence Of Heart Attack Still Decreasing In Australia? Developing More Reliable Methods For Monitoring Trends In Myocardial Infarction And Coronary Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$762,021.00
Summary
Our study is a collaboration between the University of WA and the Australian Institute of Health and Welfare to investigate population trends in incidence and outcomes of heart disease and its major sub-groups including heart attack, angina and chest pain. Using linked data from WA, we will identify the sub-groups for which trends over time are a realistic estimate of the true population trends. These will be applied to national data to monitor heart disease more accurately in Australia.
Risk Of Hepatitis C Reinfection Among People With Current Injecting Drug Use Following Successful HCV Treatment
Funder
National Health and Medical Research Council
Funding Amount
$2,245,228.00
Summary
In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs ....In Australia, hepatitis C (HCV)-related morbidity and mortality are rising. One of the most important recent breakthroughs in clinical medicine is the approval of safe, simple, interferon-free HCV therapies with cure rates >95%. Although people who inject drugs account for the majority of new and existing cases of HCV, reinfection following treatment can occur. The goal of this Project Grant is to examine HCV treatment and reinfection following successful therapy among people who inject drugs.Read moreRead less
Early Introduction Of Dietary Allergen To Reduce The Population Prevalence Of Infant Food Allergy
Funder
National Health and Medical Research Council
Funding Amount
$412,468.00
Summary
Australia has the highest recorded prevalence of childhood peanut allergy, a potentially life-threatening condition. New evidence shows introducing peanut into the diet in infancy can reduce the risk of developing peanut allergy in high risk infants, and allergy prevention guidelines now recommend giving peanut before 12 months. This study will evaluate how effective these guidelines have been in promoting earlier peanut introduction and reducing the population prevalence of peanut allergy.
Vaccination Timeliness In Aboriginal And Non-Aboriginal Infants: Risk Factors For Delayed Vaccination And Impact On Disease Burden—a Record Linkage Study
Funder
National Health and Medical Research Council
Funding Amount
$538,183.00
Summary
Vaccination has had a significant impact, but preventable infections continue to occur, perhaps due to delayed uptake of scheduled doses. For the first time, we will link vaccination and other health records to: provide accurate estimates of the impact of vaccination; identify reasons for delayed vaccination; and quantify the expected reduction in disease burden if vaccination timeliness was improved. The study will help determine who would benefit most from efforts to improve timeliness.
Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.
POPULATION-LEVEL RELEVANCE OF RISK FACTORS FOR CANCER
Funder
National Health and Medical Research Council
Funding Amount
$319,692.00
Summary
This research will provide novel up-to-date evidence-based information on the population-level relevance of lifestyle-related risk factors for cancer in Australia, by applying an advanced disease burden measure to established Australian cohort studies. This knowledge on the national cancer burden is essential for targeting cancer interventions for those at highest risk and evaluating their effectiveness.