Dr. Ivo Mueller is global leader in the study of non-African malaria with a special focus on the SW Pacific and on P. vivax. His research at the Walter & Eliza Hall Institute focuses on population-based studies of host-vector-parasite interactions and their effect on burden and transmission of different malaria parasites as well as improving treatment & prevention of malaria in children and pregnant mothers and thereby contributing to the development of new tools to control and eliminate malaria
Christine Roberts’ research program uses the most advanced research methods to address new challenges in maternal and child health in a portfolio that extends from bench-to-bedside-to-policy. Four interrelated themes target: accurate identification of at-risk pregnancies; maternity care requirements to improve outcomes in future pregnancies; clinical trials to provide best evidence for obstetric practice; and an improved ability to respond rapidly to emerging issues in policy and practice.
Discovery And Translation Of Disease Causing Mutations With Genomic And Transcriptomic Data
Funder
National Health and Medical Research Council
Funding Amount
$622,655.00
Summary
This proposal will develop and apply methods for the analysis of genetic data generated from family and cohort studies of collaborators to identify genetic risk loci for both neurogenetic disorders and infectious diseases, particularly malaria. The project will combine large-scale datasets of different types and across different species. This will require the development and application of multivariate statistical analysis methods suited to the data.
Women's Hormones And Health Across The Adult Life Span
Funder
National Health and Medical Research Council
Funding Amount
$951,005.00
Summary
Sex hormones are important in younger and older women’s health. However, normal levels of sex hormones for women of different ages and the extent to which sex hormones are associated with common health outcomes are yet to be established. These issues will be systematically studied in comprehensive, community-based studies of younger and older Australian women. The findings will be immediately translated into clinical practice guidelines and community education.
Advancing Aboriginal Australian Oral Health Through Intervention Studies, Longitudinal Studies, Modelling And Surveillance
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Indigenous Australians experience worse oral health than their non-Indigenous counterparts. This Fellowship aims to advance Aboriginal Australian oral health through intervention studies, longitudinal studies, modelling & surveillance. The fellowship will capitalise on past collaborations with local, national and international researchers of repute, and seek to forge new partnerships that will be of benefit to Indigenous oral health at a global level.
‘Breaking The Cycle’ Of Crime - Improved Health And Justice Outcomes For Offenders Through Effective Interventions
Funder
National Health and Medical Research Council
Funding Amount
$838,845.00
Summary
Offender population ensure some of the worst health outcomes in the community and impose a significant burden on society. Addressing their health and criminogenic needs through effective interventions not only improves individual outcomes but has profound financial and societal benefits. This fellowship will focus on developing effective interventions in the areas of infectious diseases, mental health and violence, including domestic and family violence.
Integration Of Biostatistics And Mathematical Modelling To Improve The Control Of Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$622,655.00
Summary
Improving the control of infectious diseases requires the evaluation of interventions that prevent disease at the population level and successfully treat infections at the individual level. This proposal brings together advanced biostatistical research with mathematical modelling to discover novel methods for evaluating antimalarial treatments and malaria vaccine candidates, leading to new insights in infectious disease control and building capacity in this emerging cross-disciplinary field.
Enhancing Disease Vector Biosecurity Through High Density Molecular Markers
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
The outbreak of several diseases spread by mosquitoes is increasing rapidly around the world, driven by increased people movement spreading both viruses and disease vectors, a lack of effective vaccines and changing climatic conditions. In this proposal I aim to develop cutting edge molecular tools for identifying pathways of exotic mosquito introductions into Australia and a program that uses bacteria living inside mosquitoes in novel ways for disease suppression.
Unlocking The Health Effects Of Sitting To Reduce Chronic Disease
Funder
National Health and Medical Research Council
Funding Amount
$638,517.00
Summary
This fellowship involves a series of studies that will fill gaps in evidence to inform national and international public health and clinical guideline recommendations on sitting time. It will provide crucial evidence on dose-response relationships, underlying mechanisms and the feasibility of making the relevant behavioural changes, providing more-precise evidence-based contributions to the development of public health policy and guidelines on sitting time.
Understanding And Addressing Socioeconomic Inequalities In Diet, Physical Activity And Obesity
Funder
National Health and Medical Research Council
Funding Amount
$714,745.00
Summary
Obesity is one of Australia's most significant public health problems, and is particularly prevalent amongst people experiencing socioeconomic disadvantage (e.g. with low education levels or low incomes). Currently the most effective means of addressing this increased risk is unknown. The proposed research will directly address this evidence gap by generating new knowledge on the causes of and effective strategies for reducing socioeconomic inequalities in diet, physical activity and obesity.