Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the rel ....Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the release of cryptic genetic variation that can allow novel morphologies to evolve in new environments. The project expects to provide further understanding of how species may potentially adapt to environmental stresses in the future, including climate change.Read moreRead less
Choosing to persist: sexual selection in the wild. This project aims to investigate the role of sexual selection in maintaining healthy wild populations. The prevailing story of sexual selection, in which the sexes either compete for or choose the other sex, has been of extravagant ornaments and displays that drive species to extinction. However, an opposing story has emerged, with elaborate ornaments reflecting a healthy genome and sexual selection instead sweeping away damaging genetic mater ....Choosing to persist: sexual selection in the wild. This project aims to investigate the role of sexual selection in maintaining healthy wild populations. The prevailing story of sexual selection, in which the sexes either compete for or choose the other sex, has been of extravagant ornaments and displays that drive species to extinction. However, an opposing story has emerged, with elaborate ornaments reflecting a healthy genome and sexual selection instead sweeping away damaging genetic material. This project expects to generate new knowledge on the potential for sexual selection to remove harmful mutations in the wild. Expected outcomes include determining if sexual selection can help prevent extinction in wild populations, with direct benefits for conservation programs.Read moreRead less
Australian Heritage: constructing the first Aboriginal reference genome. This project aims to use DNA sequencing technologies to generate the first complete and accurate Aboriginal genomes, along with maps of genomic variation around Australia. It will combine a range of advanced analytical methods to integrate past and present indigenous genetic diversity from human populations around the world into a new pan-human reference genome. This project will lead to a step change in our understanding o ....Australian Heritage: constructing the first Aboriginal reference genome. This project aims to use DNA sequencing technologies to generate the first complete and accurate Aboriginal genomes, along with maps of genomic variation around Australia. It will combine a range of advanced analytical methods to integrate past and present indigenous genetic diversity from human populations around the world into a new pan-human reference genome. This project will lead to a step change in our understanding of global human genomic variants and provide a range of new targets relevant to medical biology, while significantly improving our knowledge of human genetic history and its consequences in the modern day.Read moreRead less
Fire regimes and demographic responses interact to threaten woody species. This project aims to extend and test an Interval Squeeze conceptual model which predicts fire-climate interaction effects on plant species persistence. Complex processes affect future species persistence, and an evidence-based conceptual framework is needed. Working across two continents, this project will quantify the effects of projected shortening of fire intervals, lower rainfall and elevated temperatures on woody pla ....Fire regimes and demographic responses interact to threaten woody species. This project aims to extend and test an Interval Squeeze conceptual model which predicts fire-climate interaction effects on plant species persistence. Complex processes affect future species persistence, and an evidence-based conceptual framework is needed. Working across two continents, this project will quantify the effects of projected shortening of fire intervals, lower rainfall and elevated temperatures on woody plant species. Field evidence spans global change predictions, ecosystems and species representing key system dominants and functional response types. The project will synthesise this data into larger simulation models and extend its conceptual framework to directly inform conservation and fire management.Read moreRead less
Male-male competition vs female choice: same-same or something different? This project aims to increase our understanding of the phenotypic, genetic and genomic outcomes of evolution, by both enhancing, and reversing, sexual selection in laboratory fruit flies. In doing so, this project expects to separate the entangled effects of female choice and male competition, generating new knowledge in evolutionary ecology and genetics. Expected outcomes of this project include identifying the separate m ....Male-male competition vs female choice: same-same or something different? This project aims to increase our understanding of the phenotypic, genetic and genomic outcomes of evolution, by both enhancing, and reversing, sexual selection in laboratory fruit flies. In doing so, this project expects to separate the entangled effects of female choice and male competition, generating new knowledge in evolutionary ecology and genetics. Expected outcomes of this project include identifying the separate molecular effects on the genome of selection through male competition and female choice. This should provide significant benefits in understanding the role of different forms of sexual selection in removing mutations and maintaining population fitness: vital factors in securing the long term viability of vulnerable species.Read moreRead less
Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforceme ....Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforcement systems to provide a comprehensive account of social and criminal justice impacts of injection drug use and methamphetamine use in Australia for the first time. Read moreRead less
Creating evidence-based public open space standards for apartment residents. This project aims to examine how to create public open space for apartment residents. It will (1) identify how apartment dwellers use public open space, including which spaces are used and why; and (2) test whether public open space use compensates for reduced apartment/building space. With less private space, apartment residents are assumed to rely on public spaces for physical, social and recreational activities. Yet ....Creating evidence-based public open space standards for apartment residents. This project aims to examine how to create public open space for apartment residents. It will (1) identify how apartment dwellers use public open space, including which spaces are used and why; and (2) test whether public open space use compensates for reduced apartment/building space. With less private space, apartment residents are assumed to rely on public spaces for physical, social and recreational activities. Yet little is known about which spaces they use and why, and what they would prefer. Expected outcomes include tailored, equitable evidence-based recommendations for public open space planning and apartment design guidelines. Benefits include the delivery of sustainable high-density precincts that cater to community needs.Read moreRead less
The impact of gambling advertising, promotions, and sponsorship on children. This project aims to provide new and informative qualitative data aimed at preventing and reducing children’s exposure to gambling advertising, promotion and sponsorship (GAPS) in sport. It uses a Commercial Determinants of Health Framework which investigates the impact of industry mechanisms on health outcomes. It explores this issue from three perspectives - children; sporting organisations; and policy makers. The pro ....The impact of gambling advertising, promotions, and sponsorship on children. This project aims to provide new and informative qualitative data aimed at preventing and reducing children’s exposure to gambling advertising, promotion and sponsorship (GAPS) in sport. It uses a Commercial Determinants of Health Framework which investigates the impact of industry mechanisms on health outcomes. It explores this issue from three perspectives - children; sporting organisations; and policy makers. The project will have significant policy benefits by providing important evidence about the impact of gambling industry marketing strategies within sport, the decision making processes associated with gambling policy, and identifying leverage points for improving strategies to prevent GAPS from having a negative impact on children. Read moreRead less
Saving seagrass from climate change. This research aims to test whether seagrass ecosystems can be safeguarded from climate change impacts by enhancing genetic connectivity in range edge populations using novel genetic rescue approaches. We will use the range edge seagrass meadows of the UNESCO World Heritage Site of Shark Bay as our model, which was significantly impacted by a marine heat wave in 2010/2011. The project will generate new knowledge on how seagrasses can adapt and survive in situ. ....Saving seagrass from climate change. This research aims to test whether seagrass ecosystems can be safeguarded from climate change impacts by enhancing genetic connectivity in range edge populations using novel genetic rescue approaches. We will use the range edge seagrass meadows of the UNESCO World Heritage Site of Shark Bay as our model, which was significantly impacted by a marine heat wave in 2010/2011. The project will generate new knowledge on how seagrasses can adapt and survive in situ. Expected outcomes are improved conservation, management and restoration practices for seagrass meadows. This should provide significant benefits for long-term resilience of this economically and culturally significant ecosystem.Read moreRead less
Dating West Antarctic ice sheet collapse using molecular sequence data. This project aims to investigate the past stability and configuration of the West Antarctic Ice Sheet by examining genomic signatures in present day bottom-dwelling Antarctic marine animals. By employing this novel biological approach this project will provide an independent test of the hypothesis that the West Antarctic Ice Sheet collapsed during the most recent interglacial period and formed a trans-Antarctic seaway. Expec ....Dating West Antarctic ice sheet collapse using molecular sequence data. This project aims to investigate the past stability and configuration of the West Antarctic Ice Sheet by examining genomic signatures in present day bottom-dwelling Antarctic marine animals. By employing this novel biological approach this project will provide an independent test of the hypothesis that the West Antarctic Ice Sheet collapsed during the most recent interglacial period and formed a trans-Antarctic seaway. Expected project outcomes include increased resolution of the most recent collapse of the West Antarctic Ice Sheet. This project should provide benefits in predicting future ice sheet collapse and its impact on sea level rise, which is a key uncertainty resulting from climate change.Read moreRead less