Understanding third hand exposure of Australian people to methamphetamine. In Australia, there is high community concern around inadvertent exposure to methamphetamine residues in contaminated houses. In this proposal, an interdisciplinary research team aim to engage with public health authorities and public housing industry to conduct collaborative research on total exposure to methamphetamine in contaminated indoor environments. The project will assess exposure pathways (via air, dust, surface ....Understanding third hand exposure of Australian people to methamphetamine. In Australia, there is high community concern around inadvertent exposure to methamphetamine residues in contaminated houses. In this proposal, an interdisciplinary research team aim to engage with public health authorities and public housing industry to conduct collaborative research on total exposure to methamphetamine in contaminated indoor environments. The project will assess exposure pathways (via air, dust, surfaces) and link them with methamphetamine levels in samples from occupants (urine, hair). The project is expected to significantly enhance our understanding of how third hand exposure leads to internal exposure in humans. This knowledge provides evidence for policies on residential indoor exposures and remediation strategies.Read moreRead less
Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessm ....Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessment on the impact of biomarker stability on wastewater-based epidemiology estimates using wastewater samples from ~65% of the Australian population. The project expects to generate knowledge to expand the application of wastewater-based epidemiology to reliably quantify exposure and status of well-being even in remote areasRead moreRead less
E. coli as an indicator of faecal contamination in the Australian context. The goal of this research is to improve our ability to use Escherichia coli as an indicator of water quality by determining the extent to which non-faecal sources of E. coli contribute to coliform counts and to develop a method to differentiate non-faecal E. coli from those that are faecal derived.
Exposure mapping - combining wastewater analysis with human biomonitoring. This project aims to develop a spatial and temporal understanding of chemical exposure in the Australian population. The project will use wastewater samples collected from over 100 catchments (65% of Australian population) during the 2016 Census to spatially resolve human exposure to chemicals. These data will then form the basis for focused human biomonitoring using pooled surplus pathology samples. The integration of ....Exposure mapping - combining wastewater analysis with human biomonitoring. This project aims to develop a spatial and temporal understanding of chemical exposure in the Australian population. The project will use wastewater samples collected from over 100 catchments (65% of Australian population) during the 2016 Census to spatially resolve human exposure to chemicals. These data will then form the basis for focused human biomonitoring using pooled surplus pathology samples. The integration of wastewater and biomonitoring data will allow the creation of a national hazard specific exposure map that can be compared with geospatial data on disease risk and socioeconomic indicators (via ABS information). The benefits include the capability to identify and manage exposure risks to public health.Read moreRead less
Coral resilience and the optimal management of biodiversity. This project aims to examine the resilience of coral biodiversity to disturbances and build on recently developed genomic resources to explore the genotypic traits that confer thermal tolerance. The project will research how coral biodiversity responds to climatic disturbances; the potential for acclimation and adaptation; and the best ways to monitor, manage and restore biodiversity. The project is expected to generate tangible outcom ....Coral resilience and the optimal management of biodiversity. This project aims to examine the resilience of coral biodiversity to disturbances and build on recently developed genomic resources to explore the genotypic traits that confer thermal tolerance. The project will research how coral biodiversity responds to climatic disturbances; the potential for acclimation and adaptation; and the best ways to monitor, manage and restore biodiversity. The project is expected to generate tangible outcomes and strategies to optimise the management of Australia’s coral biodiversity while engaging the public through museum-based outreach, in collaboration with government, regulatory sectors and an industry group. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100129
Funder
Australian Research Council
Funding Amount
$249,000.00
Summary
Microflow ultra high pressure liquid chromatography - high resolution mass spectrometry for chemical exposure monitoring. Microflow ultra high pressure liquid chromatography – high resolution mass spectrometry for chemical exposure monitoring: Identifying new chemicals of interest in environmental or biological samples is the first critical step toward understanding their impact to human and environment. A state-of-the-art microflow ultra high performance liquid chromatography high resolution ma ....Microflow ultra high pressure liquid chromatography - high resolution mass spectrometry for chemical exposure monitoring. Microflow ultra high pressure liquid chromatography – high resolution mass spectrometry for chemical exposure monitoring: Identifying new chemicals of interest in environmental or biological samples is the first critical step toward understanding their impact to human and environment. A state-of-the-art microflow ultra high performance liquid chromatography high resolution mass spectrometer is fundamental to extend our research capabilities to new environmental contaminants and environmental exposure biomarkers, as well as consumption biomarkers of new illicit drugs and their metabolites. This instrument will fill an important gap in our capacity to link health/ecological risk to unknown chemicals and will allow interdisciplinary researchers to advance work in environmental toxicology, chemistry and forensics.Read moreRead less