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Discovery Early Career Researcher Award - Grant ID: DE120102784
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Water-swellable rubber with nanoparticle-enabled super capacity as smart water-leakage sealant. A novel water-swellable rubber (WSR) sealant with continuous hydrophobic phase and isolated hydrophilic phase is developed for stopping water leakage from gaps and cracks. Nanoparticle-enabled blocks and network channels in rubber matrix effectively improve the integrity and capability of WSR as smart water-leakage sealants in various applications.
Bioactive Polymer Platelets. This project aims to develop polymers that can be self-assembled into 2D structures. Most nanoparticles developed for drug delivery are spherical. However these are not always the most efficacious as theory suggest that non-spherical nanoparticles have longer circulation times. It is proposed that discoid morphologies may be advantageous as they tend to migrate to the vascular membrane and adhere more efficiently. The polymers developed by this project will be tailor ....Bioactive Polymer Platelets. This project aims to develop polymers that can be self-assembled into 2D structures. Most nanoparticles developed for drug delivery are spherical. However these are not always the most efficacious as theory suggest that non-spherical nanoparticles have longer circulation times. It is proposed that discoid morphologies may be advantageous as they tend to migrate to the vascular membrane and adhere more efficiently. The polymers developed by this project will be tailored towards bioactive and biocompatible material to create a drug delivery platform for more efficient disease treatment. The outcome will be better understanding on how polymer platelets can be obtained and how they compare in their biological activity with spherical nanoparticles.Read moreRead less
Polymer nanodiscs. This project aims to produce disc-shaped polymer nanomaterials by utilising a new self-assembly concept based on oppositely charged polymers. This project expects to generate a modular technology that allows synthesis and control over the geometry and functionality of polymer nanoparticles. This level of control will permit a precise investigation of polymer nanodisc properties for nanomedicine applications. Expected outcomes of this project will be the fundamental understandi ....Polymer nanodiscs. This project aims to produce disc-shaped polymer nanomaterials by utilising a new self-assembly concept based on oppositely charged polymers. This project expects to generate a modular technology that allows synthesis and control over the geometry and functionality of polymer nanoparticles. This level of control will permit a precise investigation of polymer nanodisc properties for nanomedicine applications. Expected outcomes of this project will be the fundamental understanding of how nanoparticle geometry affects particle-cell interaction and how nanoscale polymer discs can be used to mimic biological nanoparticles in shape and function.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100007
Funder
Australian Research Council
Funding Amount
$386,500.00
Summary
A modular toolbox of novel polymer nanorods for better tissue penetration. This project aims to establish a suite of design parameters to provide new avenues for understanding and manipulating tissue infiltration by future therapeutic nanoparticles. The project expects to develop an innovative technology that allows independent control over nanoparticle geometry, functionality, and mechanical and surface properties. This level of control over the synthesis of polymer nanoparticles with distinct ....A modular toolbox of novel polymer nanorods for better tissue penetration. This project aims to establish a suite of design parameters to provide new avenues for understanding and manipulating tissue infiltration by future therapeutic nanoparticles. The project expects to develop an innovative technology that allows independent control over nanoparticle geometry, functionality, and mechanical and surface properties. This level of control over the synthesis of polymer nanoparticles with distinct physicochemical properties will enable precise adjustment and investigation of discrete particle properties. The project will reshape fundamental knowledge of nanoparticle design by demonstrating the centrality of particle shape, stiffness, and heterogeneity. The outcomes will significantly advance the science of polymer nanoparticle synthesis control, aiding the development of novel and more effective polymer nano-therapeutics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100002
Funder
Australian Research Council
Funding Amount
$808,191.00
Summary
A facility for laser-based automated manufacturing of carbon composites. This project aims to create an advanced manufacturing facility for carbon-composites research by integrating laser-based processing and robotic automation. It will enable fundamental research on rapid processing of high-performance thermoplastics and metal-composite hybrids, including functionalisation of the composite through nano-material coating technology, and new instrumentation for structural health monitoring. The fa ....A facility for laser-based automated manufacturing of carbon composites. This project aims to create an advanced manufacturing facility for carbon-composites research by integrating laser-based processing and robotic automation. It will enable fundamental research on rapid processing of high-performance thermoplastics and metal-composite hybrids, including functionalisation of the composite through nano-material coating technology, and new instrumentation for structural health monitoring. The facility will significantly enhance the research capability in the newly established ARC Training Centre for Automated Manufacture of Advanced Composites, which will engage with Australian industry to improve productivity and material performance for industry sectors such as aerospace, automotive, marine, and sport.Read moreRead less
Nanoparticles to combat cellular dysfunction. This project aims to design, synthesise and characterise nanoparticles that can mediate the adverse effects of reactive oxygen species. The project expects to develop nanoparticles with tailored chemical functionality to modulate the concentration of reactive oxygen species and develop a platform technology for addressing conditions where reactive species are overproduced. The project will research how nanoparticles’ physicochemical properties affect ....Nanoparticles to combat cellular dysfunction. This project aims to design, synthesise and characterise nanoparticles that can mediate the adverse effects of reactive oxygen species. The project expects to develop nanoparticles with tailored chemical functionality to modulate the concentration of reactive oxygen species and develop a platform technology for addressing conditions where reactive species are overproduced. The project will research how nanoparticles’ physicochemical properties affect their activity, and how they affect cellular function, tissue morphology and particle transport in a biological milieu. The project is expected to benefit the advanced manufacturing, veterinary and medical sectors and could lead to new chemotherapeutics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100116
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Facilities of thermophysical characterisations at nanometre scale for development of advanced materials, energy technologies and biomedical components. Australia's energy, mining, metallurgical, defence, pharmaceutical and biomedical industries are spearheading the advancement of technologies in the global competitive market. They are the engines of Australian economic strength. Future progress of these industries will be largely driven by advances in materials. The installation of the propose ....Facilities of thermophysical characterisations at nanometre scale for development of advanced materials, energy technologies and biomedical components. Australia's energy, mining, metallurgical, defence, pharmaceutical and biomedical industries are spearheading the advancement of technologies in the global competitive market. They are the engines of Australian economic strength. Future progress of these industries will be largely driven by advances in materials. The installation of the proposed facilities will add a new dimension to high-level research performance and significantly enhance the capability for characterisation of various forms of materials and biomedical components in Australia. The continual development of advanced materials and energy technology will potentially provide a sustainable means for meeting the increasing global challenge for the industries.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL190100139
Funder
Australian Research Council
Funding Amount
$3,185,850.00
Summary
New Artificial Leaf for Efficient Solar Fuel Production . The Fellowship aims to develop next-generation materials that harness solar energy to produce valuable fuels and chemicals from water and carbon dioxide, replacing fossil fuels. The program will design new semiconductor materials to revolutionise solar-to-fuel technologies that currently have very low efficiency. The expected outcomes include innovative systems such as wireless artificial leaves that mimic natural photosynthesis for effic ....New Artificial Leaf for Efficient Solar Fuel Production . The Fellowship aims to develop next-generation materials that harness solar energy to produce valuable fuels and chemicals from water and carbon dioxide, replacing fossil fuels. The program will design new semiconductor materials to revolutionise solar-to-fuel technologies that currently have very low efficiency. The expected outcomes include innovative systems such as wireless artificial leaves that mimic natural photosynthesis for efficient hydrocarbon production, carbon dioxide reduction, and water purification. The expected benefits include next-generation solar fuel and chemical generation technologies, and research capabilities to position Australia as a global leader in the transition to a decarbonised economy.Read moreRead less
Unlocking the ion selectivity of lithium superionic conductor membranes. This project aims to address a longstanding challenge in designing advanced membranes to enable sustainable lithium refining by unlocking the ion selectivity of lithium superionic conductors. This project expects to generate new knowledge in the areas of membrane science and emerging nanoionics by using interdisciplinary approaches. Expected outcomes of this project include a novel class of lithium separation membranes and ....Unlocking the ion selectivity of lithium superionic conductor membranes. This project aims to address a longstanding challenge in designing advanced membranes to enable sustainable lithium refining by unlocking the ion selectivity of lithium superionic conductors. This project expects to generate new knowledge in the areas of membrane science and emerging nanoionics by using interdisciplinary approaches. Expected outcomes of this project include a novel class of lithium separation membranes and their fabrication techniques. This should provide significant benefits in improving lithium extraction and recycling efficiency, reducing their environmental impact and building the research capacity in advanced membrane manufacturing and critical mineral refining in Australia. Read moreRead less