The Role Of The Zinc Finger Transcriptional Repressor Znf238 During Nerve Cell Maturation
Funder
National Health and Medical Research Council
Funding Amount
$394,264.00
Summary
Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.
Improving The Quality, Efficiency And Outcomes Of Stroke Care: Transforming Policy And Practice
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
This Fellowship supports an innovative body of research focussed on interventions to improve the care and outcomes of stroke. In Australia, stroke is a leading cause of death and disability. Unfortunately, variability in clinical care is resulting in some preventable disability. Over the next 4 years A/Prof Cadilhac will conduct clinical trials (n=2) and observational studies (n=3) aimed at improving the health system and outcomes of stroke. She uses economic evaluation to ensure findings are us ....This Fellowship supports an innovative body of research focussed on interventions to improve the care and outcomes of stroke. In Australia, stroke is a leading cause of death and disability. Unfortunately, variability in clinical care is resulting in some preventable disability. Over the next 4 years A/Prof Cadilhac will conduct clinical trials (n=2) and observational studies (n=3) aimed at improving the health system and outcomes of stroke. She uses economic evaluation to ensure findings are used for changing policy.Read moreRead less
Neuroimaging In Mental Health: The Quest For Clinically Useful Biomarkers
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
To ultimately improve treatment of mental illness, this research program aims to detect robust and reliable neuroimaging markers that are associated with affective disorders by pooling data from many samples across the world. Moreover, this research aims to develop alternative biological-based classifications of mental illness in young people, and evaluate their clinical value by examining their predictive value for treatment response and disease course.