Climate change: adaptation and resilience in the face of uncertainty. Climate change poses a wide range of challenges to Australia's agricultural sector and for the management of natural ecosystems. These challenges are recognised in the National Research Priorities 1, An Environmentally Sustainable Australia, and 4, Safeguarding Australia. The potential economic costs of climate change to vital national assets such as the Murray-Darling Basin and the Great Barrier Reef, amount to billions of do ....Climate change: adaptation and resilience in the face of uncertainty. Climate change poses a wide range of challenges to Australia's agricultural sector and for the management of natural ecosystems. These challenges are recognised in the National Research Priorities 1, An Environmentally Sustainable Australia, and 4, Safeguarding Australia. The potential economic costs of climate change to vital national assets such as the Murray-Darling Basin and the Great Barrier Reef, amount to billions of dollars per year, and ecological costs are even more significant. Uncertainty about the rate at which climate change will take place and about effects in different regions is central to the problem. This project will explore adaptive management strategies that promote resilience in the face of uncertainty.
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Deciphering genome function in animal development. The normal development of an embryo depends on complex and finely tuned gene regulatory mechanisms. In this Fellowship, I will use sophisticated new technologies to discover which of our 30,000 genes is important for embryonic development, reveal the roles of these genes, and identify the control mechanisms that can go awry to cause birth defects. Our research will suggest new ways to diagnose and deal with these conditions, and will be applicab ....Deciphering genome function in animal development. The normal development of an embryo depends on complex and finely tuned gene regulatory mechanisms. In this Fellowship, I will use sophisticated new technologies to discover which of our 30,000 genes is important for embryonic development, reveal the roles of these genes, and identify the control mechanisms that can go awry to cause birth defects. Our research will suggest new ways to diagnose and deal with these conditions, and will be applicable to stem cell technologies, tissue regeneration, cancer biology, conservation, pest management and livestock breeding, thus delivering significant economic and social benefits to Australia. Read moreRead less
Sustainable reform of the Murray-Darling system: Property rights, uncertainty and institutions. The project will develop tools for the modelling of uncertainty in the absence of probabilities and with imperfect knowledge about possible events. It will also formalise and assess the precautionary principle for the sustainable management of complex systems. Finally, the project will apply these tools to analyse and improve policies for the reform of property rights, institutions and land and water ....Sustainable reform of the Murray-Darling system: Property rights, uncertainty and institutions. The project will develop tools for the modelling of uncertainty in the absence of probabilities and with imperfect knowledge about possible events. It will also formalise and assess the precautionary principle for the sustainable management of complex systems. Finally, the project will apply these tools to analyse and improve policies for the reform of property rights, institutions and land and water management in the Murray?Darling system. The project will assist in the formulation of sustainable responses to problems of drought and irrigation related salinity in the Murray?Darling system.Read moreRead less
Cellular Plasticity in the Brain: discovering molecular mechanisms controlling the production of neurons during brain development, function, ageing and disease. The program aims to understand the mechanisms regulating Brain Plasticity - this recently discovered property of the brain to respond to environmental stimuli, both physiological and pathological, by producing new functional neurons. Specifically, the program will discover how the brain's stem cells are stimulated to produce new neurons. ....Cellular Plasticity in the Brain: discovering molecular mechanisms controlling the production of neurons during brain development, function, ageing and disease. The program aims to understand the mechanisms regulating Brain Plasticity - this recently discovered property of the brain to respond to environmental stimuli, both physiological and pathological, by producing new functional neurons. Specifically, the program will discover how the brain's stem cells are stimulated to produce new neurons. This understanding will significantly expand our knowledge of how the brain develops, and how functions, like memory, are modulated by neuronal replacement. Discoveries will underpin the development of, in association with Australia's biotechnology sector, a new generation of therapeutics, which treat neurological diseases, like Stroke, by stimulating the production of functional neurons.Read moreRead less