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  • Funded Activity

    Mapping Nerve Cells In The Retina

    Funder
    National Health and Medical Research Council
    Funding Amount
    $268,857.00
    More information
    Funded Activity

    Implementation And Evaluation Of A Diabetes Intervention Program In Indigenous Australian Communities.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $173,625.00
    Summary
    Approximately 700,000 Australians have type 2 diabetes (also termed maturity-onset diabetes or non-insulin dependent diabetes), which is a condition associated with reduced lifespan, eye disease, heart disease, renal disease, stroke, and foot complications leading to amputation. Indigenous Australians are at particularly high risk, with over 30% of adults affected by this condition in a number of communities, associated with significant morbidity and mortality. Early diagnosis, healthy lifestyle .... Approximately 700,000 Australians have type 2 diabetes (also termed maturity-onset diabetes or non-insulin dependent diabetes), which is a condition associated with reduced lifespan, eye disease, heart disease, renal disease, stroke, and foot complications leading to amputation. Indigenous Australians are at particularly high risk, with over 30% of adults affected by this condition in a number of communities, associated with significant morbidity and mortality. Early diagnosis, healthy lifestyle modification and tight control of the blood sugar levels, blood pressure and cholesterol are the keys to preventing the complications of diabetes. Self-management is central to success, and education, support and encouragement play an important role. This research project incorporates an education program that has been developed in partnership with the indigenous health team at Cherbourg. Particular strengths include the emphasis on family involvement and community support. The central role of the indigenous health team will ensure continuity of benefit to the community. If proven to be effective, the program could be used as a model for interventions in other community settings to reduce the burden from type 2 diabetes in the indigenous Australian population.
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    Funded Activity

    Primary Health Care Errors Study: Qualification And Quantification Of Errors Occurring In General Practice

    Funder
    National Health and Medical Research Council
    Funding Amount
    $191,000.00
    Summary
    The General Practice Errors Study (GPES) is a project that aims to examine errors that GPs notice in their daily practice, that affect patient well-being or care. Very little work has been done on this subject in General Practice in any other country, and Australia is the only country with previous research that has attempted to describe GP errors with the Quality in Australia Health Care Study (QAHCS). However, we have so far not had any research that has been done on a representative sample of .... The General Practice Errors Study (GPES) is a project that aims to examine errors that GPs notice in their daily practice, that affect patient well-being or care. Very little work has been done on this subject in General Practice in any other country, and Australia is the only country with previous research that has attempted to describe GP errors with the Quality in Australia Health Care Study (QAHCS). However, we have so far not had any research that has been done on a representative sample of GPs, or been able to quantify the frequency with which different types of errors occur. This study plans to ask a representative sample of GPs in both urban and rural areas to report their errors, so that we can try to quantify the incidence and prevalence of these different error types. No previous work has been done in Primary care which has attempted to determine the rate of recognized errors that occur in the community. In addition, since the last major work on this topic was done between 1993 and 1998, there have been many changes to General Practice, especially in the area of computerisation, and the types of problems that GPs face now may have changed significantly. Anonymous reporting is very important in order to encourage health professionals to admit to their mistakes, and in the past, projects have used paper based reporting forms, making it difficult to offer anonymity and requiring protection for participants under a Commonwealth Act of Parliament. However the GPES project will be the first major study of General Practice errors that uses an on-line anonymous reporting form, and high level encryption, located on a secure web-site, to encourage honest reporting. The reporting form was trialled in the 2001 pilot study. By analysing the types of errors occurring, and their contributing factors, we can target at-risk population groups and develop strategies to improve patient care and prevent future harm.
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    Funded Activity

    Evaluating The Effectiveness Of Comprehensive Primary Health Care In Local Communities

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,635,268.00
    Summary
    This research will develop and implement a program logic evaluation in order to assess the effectiveness of various models of primary heatlh care service delivery. Although comprehensive primary health care holds considerable promise to meet the growing demands on the health system, it has not been thoroughly evaluated. Comprehensive primary health care is a large and complex area, therefore part of the project focuses on services and client experiences in two chromic diseases: diabetes and depr .... This research will develop and implement a program logic evaluation in order to assess the effectiveness of various models of primary heatlh care service delivery. Although comprehensive primary health care holds considerable promise to meet the growing demands on the health system, it has not been thoroughly evaluated. Comprehensive primary health care is a large and complex area, therefore part of the project focuses on services and client experiences in two chromic diseases: diabetes and depression
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    Funded Activity

    The FaXeS Study. Offering Fragile X Carrier Testing To Women: Comparing Prenatal And Preconception Screening.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $432,883.00
    Summary
    Fragile X syndrome is the leading cause of inherited intellectual disability. A genetic screening test is available to detect carriers of this condition. Using questionnaires and interviews we will directly compare carrier screening in pregnant and non-pregnant women in the general community, looking at issues such as informed decision-making, test uptake and its predictors and cost-effectiveness. This will be critical to inform policy and guidelines for genetic screening programs.
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    Funded Activity

    The Diamond Cohort Study - Long Term Outcomes Of Depressive Symptoms In Primary Care

    Funder
    National Health and Medical Research Council
    Funding Amount
    $567,538.00
    Summary
    The diamond study follows what happens to almost 800 people with depressive symptoms whom attend general practice for care over 5 years of their life. This study will map the severity of depressive symptoms, life circumstances, use of health care services and treatments and allow us to understand factors associated with relapse and recovery from depression in order to improve care. This will assist us to develop models of care that better suit the needs of people experiencing depressive symptoms .... The diamond study follows what happens to almost 800 people with depressive symptoms whom attend general practice for care over 5 years of their life. This study will map the severity of depressive symptoms, life circumstances, use of health care services and treatments and allow us to understand factors associated with relapse and recovery from depression in order to improve care. This will assist us to develop models of care that better suit the needs of people experiencing depressive symptoms.
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    Funded Activity

    Investigating Best Practice Primary Care For Older Australians With Diabetes Using Data Linkage

    Funder
    National Health and Medical Research Council
    Funding Amount
    $522,278.00
    Summary
    This study will use data linkage to examine questions about health service use by older Australians to manage chronic conditions such as diabetes. It will lead to a better understanding of the uptake of community based care initiatives and incentives through general practice, the factors that assist or impede uptake, and the impact of these on patient outcomes such as hospitalisation. The research findings will address important questions of interest to practitioners and policy advisors.
    More information
    Funded Activity

    Are The Back Pain Guidelines Wrong?

    Funder
    National Health and Medical Research Council
    Funding Amount
    $448,300.00
    Summary
    All current clinical practice guidelines for the management of acute low back pain (LBP) agree that acute LBP has an excellent prognosis with most cases recovering within 4-6 weeks. However, the information on prognosis is contradictory and in fact chronic low back pain could develop in as many as 56% of those with acute low back pain. There is also agreement among the guidelines that the rare cases of serious disease (eg cancer) can be detected with a routine clinical examination but no study h .... All current clinical practice guidelines for the management of acute low back pain (LBP) agree that acute LBP has an excellent prognosis with most cases recovering within 4-6 weeks. However, the information on prognosis is contradictory and in fact chronic low back pain could develop in as many as 56% of those with acute low back pain. There is also agreement among the guidelines that the rare cases of serious disease (eg cancer) can be detected with a routine clinical examination but no study has evaluated the accuracy of the complete clinical assessment, and there is only limited evidence on components of the clinical assessment. We will therefore investigate the 1 year prognosis of LBP and the accuracy of the clinical assessment for detecting serious disease in the back pain population. Our study will provide the first reliable estimates of prognosis of acute LBP and the accuracy of widely recommended clinical assessment procedures and thereby allow appropriate allocation of funds to this enormous problem.
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    Funded Activity

    A Randomised Trial To Control Sexually Transmitted Infections In Remote Aboriginal Communities.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,847,403.00
    Summary
    This project will trial strategies for attaining clinical best practice in sexual health with an overall objective of reducing the high rates of sexually transmitted infection in remote Aboriginal communities in central and northern Australia. The trial will take place in 21 communities of which seven will be randomly assigned in each of the three years of the trial. This trial will determine whether strengthening primary health services can reduce the level of these infections.
    More information
    Funded Activity

    Acute Bronchitis In General Practice: What Factors Predict A Poor Outcome And Can Antibiotics Help?

    Funder
    National Health and Medical Research Council
    Funding Amount
    $393,750.00
    Summary
    In Australia acute bronchitis is one of the commonest reasons for patients to attend their general practitioner. It can have considerable impact on patients lives with patients coughing on average for two weeks, with a third spending some time in bed and a quarter not returning to their usual activities for many weeks. If they attend a general practitioner (GP) it is likely they will receive antibiotics. But researchers believe that antibiotics are over prescribed for this condition and the emer .... In Australia acute bronchitis is one of the commonest reasons for patients to attend their general practitioner. It can have considerable impact on patients lives with patients coughing on average for two weeks, with a third spending some time in bed and a quarter not returning to their usual activities for many weeks. If they attend a general practitioner (GP) it is likely they will receive antibiotics. But researchers believe that antibiotics are over prescribed for this condition and the emergence of bacterial resistance is a real concern to health authorities. GPs are therefore being urged to reduce the prescription of antibioics for this common condition. But surveys by the National Prescribing Service (NPS) indicate that this is one area where GPs find it difficult to meet national recommendations. In part this may be because GPs do not wish to undertreat or miss a serious respiratory illness. Also results from randomised controlled trials examining the effectiveness of antibiotics for acute bronchitis suggest some benefit from treatment, at least in some patients. However it is not clear who these patients are and how much benefit they would get from receiving antibiotics. This creates a great deal of uncertainity for GPs who then opt for a 'just in case prescription' for everyone presenting with acute bronchitis. Our study will re-examine the symptoms, and clinical findings of patients presenting to their GP with acute cough and explore the impact of this common illness on patients lives. We will determine who does and does not benefit from antibiotics, and give guidance to GPs about the symptoms, clinical findings and investigations that predict a poorer outcome. Evidence from this study will be incorporated into treatment guidelines for acute bronchitis leading to more rational and effective management of this common problem.
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