Innovative Patient Education For Preventing Falls After Hospital Discharge
Funder
National Health and Medical Research Council
Funding Amount
$573,186.00
Summary
Older people are at increased risk of falls after hospital discharge, but have low levels of knowledge about falls and may be reluctant to undertake falls prevention activities. Providing suitable education may reduce falls in these older patients. This randomized trial will determine if providing personalized falls prevention education in addition to usual care, reduces falls among older people after they leave hospital. Falls are the leading cause of injury among older people in Australia
Effectiveness Of Occupational Therapy Homevisits To Improve Participation After Stroke
Funder
National Health and Medical Research Council
Funding Amount
$1,774,083.00
Summary
This randomized controlled trial will determine the effectiveness of occupational therapy pre-discharge homevisits for people after stroke, with health economic evaluation conducted alongside to determine the cost-benefits. Recruiting adults from Australian rehabilitation hospitals, this study is designed to provide guidance for hospitals, policy-makers and clinical practice guideline developers on whether occupational therapy homevisits improve the level of community participation after stroke.
A Computerised Treatment Planning System For Synchrotron Radiotherapy Trials At The Australian Synchrotron’s Imaging & Medical Beamline.
Funder
National Health and Medical Research Council
Funding Amount
$646,812.00
Summary
Microbeam Radiotherapy (MRT) using synchrotron-generated X-rays has shown tremendous promise in pre-clinical trials in tumour-bearing rodents, with remarkable sparing of normal tissue. Synchrotron MRT has the potential to radically alter the way radiotherapy is performed for human cancers. Every radiotherapy patient undergoes some form of computerised treatment planning before their treatment starts. We aim to test and implement a synchrotron Treatment Planning System, as an essential step in re ....Microbeam Radiotherapy (MRT) using synchrotron-generated X-rays has shown tremendous promise in pre-clinical trials in tumour-bearing rodents, with remarkable sparing of normal tissue. Synchrotron MRT has the potential to radically alter the way radiotherapy is performed for human cancers. Every radiotherapy patient undergoes some form of computerised treatment planning before their treatment starts. We aim to test and implement a synchrotron Treatment Planning System, as an essential step in realising synchrotron radiotherapy trials.Read moreRead less
Blocking The Factor XII- Kallikrein Pathway To Limit Abdominal Aortic Aneurysm
Funder
National Health and Medical Research Council
Funding Amount
$686,995.00
Summary
Artery weakening is present in 2-5% of older adults and is an important cause of sudden death. The investigators have generated substantial preliminary data from a previous NHMRC project implicating the contact pathway in the process of artery weakening. In the current project the investigators will examine the ability of agents which are currently available or being developed for patient use in limiting the process of artery degeneration using established pre-clinical models.
ASTROID: Active Surveillance And Other TReatment OptIons For Prostate Cancer. A Randomised Controlled Trial Of Decision Aid And DVD Information Support For Men Diagnosed With Low-risk Prostate Cancer And Their Partners
Funder
National Health and Medical Research Council
Funding Amount
$782,369.00
Summary
This summary was provided in the grant application.
Reducing Unintended Pregnancies Among Female Sex Workers In Kenya Using MHealth: A Cluster Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$730,028.00
Summary
This research in Kenya aims to improve the health of female sex workers, their children and their partners through increasing uptake of family planning methods. This cluster randomised controlled trial will generate valuable evidence to inform policies and public health interventions on the effectiveness of a mobile phone delivered intervention aiming to increase sexual and reproductive health service uptake among hard-to-reach and marginalized sex workers in resource-limited settings.
The Australian, Imaging, Biomarkers And Lifestyle Study Of Ageing (AIBL) Phase III - Facilitating Early Intervention In Preclinical Alzheimer's Disease.
Funder
National Health and Medical Research Council
Funding Amount
$733,653.00
Summary
Amyloid brain scans can detect the onset of Alzheimer's disease 10-15 years before symptoms first appear. Amyloid build-up is thought to be the cause of Alzheimer's disease. The earlier that drugs designed to slow the build up of amyloid or to clear it from the brain are given, the greater the chance of benefit. This study will use the recent discoveries from the Australian AIBL study to develop the best method to find these people with brain amyloid but no symptoms for early treatment trials to ....Amyloid brain scans can detect the onset of Alzheimer's disease 10-15 years before symptoms first appear. Amyloid build-up is thought to be the cause of Alzheimer's disease. The earlier that drugs designed to slow the build up of amyloid or to clear it from the brain are given, the greater the chance of benefit. This study will use the recent discoveries from the Australian AIBL study to develop the best method to find these people with brain amyloid but no symptoms for early treatment trials to prevent dementia.Read moreRead less
Simultaneous Targeting Of Contraception And Sexually Transmitted Disease
Funder
National Health and Medical Research Council
Funding Amount
$681,380.00
Summary
This research will generate a completely novel topical contraceptive agent that becomes activated on contact with semen and will simultaneously protect the user against both unwanted fertility and sexually transmitted disease. A prototype compound has already been developed and patented. This research is aimed at the chemical optimization of this reagent, analysis of its mechanism-of-action and characterization of its anti-microbial activity against chlamydia, gonorrhoea, herpes simplex and HIV
PET Imaging Agents For The Differential Diagnosis Of Hypoxic Tumors
Funder
National Health and Medical Research Council
Funding Amount
$585,429.00
Summary
Choosing the best type of treatment from the ever increasing arsenal of chemotherapeutic agents against cancer is of critical importance. Tumor hypoxia requires specialized treatment and patient selection. Current PET imaging agents cannot differentiate between severely and mildly hypoxic tumors. We have found a new agent that can detect mildly hypoxic tumors and the aim of this grant application is to further develop this radiotracer to improve image quality and reliability of the diagnosis.
Developing A System For Comprehensive Quantitative Evaluation Of Public Health Strategies Against HIV/AIDS In Australia: Assessing The Past, Understanding The Present And Planning For The Future
Funder
National Health and Medical Research Council
Funding Amount
$407,358.00
Summary
The overall goal of this project is to develop and implement a system which will make optimal use of all available data on HIV/AIDS from different sources in Australia, uniquely integrate the data routinely into an innovative evaluation framework which will be developed using best modelling and economic practices, and conduct analyses which will improve the effectiveness and efficiency of Australia’s HIV policy and program response to prevent new infections and plan for clinical care required fo ....The overall goal of this project is to develop and implement a system which will make optimal use of all available data on HIV/AIDS from different sources in Australia, uniquely integrate the data routinely into an innovative evaluation framework which will be developed using best modelling and economic practices, and conduct analyses which will improve the effectiveness and efficiency of Australia’s HIV policy and program response to prevent new infections and plan for clinical care required for people living with HIV.Read moreRead less