Design of the cardiovascular system of living and fossil vertebrates. This project aims to understand how the heart and blood vessels evolved in mammals, birds, reptiles and fish to achieve efficiency. The heart is the most important organ for life. The project will study the structure and function of vertebrate animals’ hollow and spongy hearts to show how energetics shaped their evolution. It will measure arterial holes in bone to gauge brain and bone metabolism, which opens up a new way to me ....Design of the cardiovascular system of living and fossil vertebrates. This project aims to understand how the heart and blood vessels evolved in mammals, birds, reptiles and fish to achieve efficiency. The heart is the most important organ for life. The project will study the structure and function of vertebrate animals’ hollow and spongy hearts to show how energetics shaped their evolution. It will measure arterial holes in bone to gauge brain and bone metabolism, which opens up a new way to measure metabolism in extinct animals directly from fossils, rather than by inference from living relatives. The expected outcome is to correlate cardiovascular design and metabolic rates of organs.Read moreRead less
THE MATERNAL GUT MICROBIOTA DRIVES FOETAL THYMIC T CELL DEVELOPMENT . This project aims to investigate the role of maternal gut microbiota on foetal immune development, revealing the interaction of gut microbiota-host immunity at the early stages of new life. Significantly, the research will examine the time window when microbiota by-products from the mother reach the foetus and affect the development of immunity. Maternal by-products will be identified using cutting-edge methods to unravel the ....THE MATERNAL GUT MICROBIOTA DRIVES FOETAL THYMIC T CELL DEVELOPMENT . This project aims to investigate the role of maternal gut microbiota on foetal immune development, revealing the interaction of gut microbiota-host immunity at the early stages of new life. Significantly, the research will examine the time window when microbiota by-products from the mother reach the foetus and affect the development of immunity. Maternal by-products will be identified using cutting-edge methods to unravel the complex systems interactions in the developmental process. Outcomes include new fundamental knowledge about maternal gut microbiota composition and its relationship to the growing foetus, with benefits in informing pregnant women about their lifestyle choices, particularly their dietary habits, during pregnancy.
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Investigating a new way in which diet impacts animal biology. This project aims to investigate the importance of a new way in which diet can alter animal biology. High fat or high sugar diets increase the binding of products of metabolism to chromosomes, which can completely alter the way that DNA is packaged and read. This project will use cell culture, rodent and fly models to identify the regions of the genome that are most affected by the new process. The project will also determine whether ....Investigating a new way in which diet impacts animal biology. This project aims to investigate the importance of a new way in which diet can alter animal biology. High fat or high sugar diets increase the binding of products of metabolism to chromosomes, which can completely alter the way that DNA is packaged and read. This project will use cell culture, rodent and fly models to identify the regions of the genome that are most affected by the new process. The project will also determine whether the cell is harmed, or in fact harnesses the process to control development or metabolism. This project has implications for our understanding of the ways in which genes interact with the environment especially in times of change.Read moreRead less
Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
Improving plant reproductive success under heat stress: A sweet approach. This project aims to determine how genetic manipulation of cell wall invertase (CWIN) activity could regulate pollen germination, elongation and fruit set under heat stress using tomato as a model. Plant reproductive processes are highly susceptible to heat stress, which often leads to pollination failure and fruit and seed abortion, hence irreversible yield loss. Research has established that CWIN-mediated sugar metabolis ....Improving plant reproductive success under heat stress: A sweet approach. This project aims to determine how genetic manipulation of cell wall invertase (CWIN) activity could regulate pollen germination, elongation and fruit set under heat stress using tomato as a model. Plant reproductive processes are highly susceptible to heat stress, which often leads to pollination failure and fruit and seed abortion, hence irreversible yield loss. Research has established that CWIN-mediated sugar metabolism and signaling may play crucial roles in pollen growth and fruit set under heat stress. The intended outcome is the generation of critical knowledge that will advance understanding on reproductive development under heat stress, thereby providing significant benefits, such as novel ideas and solutions for improving crop yield.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100014
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and ....ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and marketing framework. The project will provide alternate solutions for lobster culture in bio-secure and cost effective onshore systems. The outcomes are targeted at positioning Australia at the forefront of onshore lobster aquaculture, with opportunity for technology transfer to other aquaculture sectors.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100025
Funder
Australian Research Council
Funding Amount
$4,379,165.00
Summary
ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, a ....ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, and deliver industry transformation in advanced manufacturing. Anticipated outcomes include the transformation of newly discovered materials into globally traded, high-value 2D products, enabling Australian industries to capture more wealth and jobs from this large and growing market.
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Feast or famine: how Australian plants stay productive under low phosphorus. Phosphorus (P) is in low supply in soils around the nation, and limits plant production in the Australian landscape, as well as for many tropical forests worldwide. How scarce P restricts photosynthetic capacity has remained elusive. We will determine how Australian plants achieve high phosphorus-use efficiency despite low P concentrations in leaves and soils. We will synthesise knowledge of how plants maintain producti ....Feast or famine: how Australian plants stay productive under low phosphorus. Phosphorus (P) is in low supply in soils around the nation, and limits plant production in the Australian landscape, as well as for many tropical forests worldwide. How scarce P restricts photosynthetic capacity has remained elusive. We will determine how Australian plants achieve high phosphorus-use efficiency despite low P concentrations in leaves and soils. We will synthesise knowledge of how plants maintain productivity with low P availability, and inform global models how to represent P biogeochemistry and photosynthesis to improve C-cycle estimates. The understanding of plant photosynthetic and P-saving mechanisms that emerge should provide benefits through improved ecological models and enhanced management of primary production.Read moreRead less
Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty a ....Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty and test multiple geological scenarios. This enhanced capability is important for the future of Australia's subsurface management, including urban geology and our continuously growing sustainable resources industry.Read moreRead less
Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforceme ....Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforcement systems to provide a comprehensive account of social and criminal justice impacts of injection drug use and methamphetamine use in Australia for the first time. Read moreRead less