From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100094
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnit ....The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnitude improvement in the clarity of our view of this central component of the Galaxy. The project also aims to enable Mopra to serve as a key element in the Australian Long Baseline Array. The project aims to ensure Australian involvement in three grand design international endeavours.Read moreRead less
Multi-model predictions of ecosystem flux under climate change based on novel genetic and image analysis methods. Improving the forecasts of ecosystem shifts must be a key focus of future ecological research if we are to preserve our unique Australian landscapes. Our proposal is of clear benefit to Australia because of the urgent need for integrated methods to predict the cumulative impact of shifts in climate and land use. We will also contribute innovative tools involving genetic and image ana ....Multi-model predictions of ecosystem flux under climate change based on novel genetic and image analysis methods. Improving the forecasts of ecosystem shifts must be a key focus of future ecological research if we are to preserve our unique Australian landscapes. Our proposal is of clear benefit to Australia because of the urgent need for integrated methods to predict the cumulative impact of shifts in climate and land use. We will also contribute innovative tools involving genetic and image analysis, and state-of-the-art modelling. The damage modern human societies are inflicting on global environments has led to a great demand for logistically feasible and cost-effective ways to prevent biodiversity loss.Read moreRead less
ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100141
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality c ....High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality changes, pollution histories, recent geomorphological change, land-use change, introduction of invasive species and the occurrence of bushfires. A better understanding of the occurrence and timing of these major environmental issues is of national and regional importance.Read moreRead less
Creating a national time and frequency network for Australia. This project will develop the means to distribute accurate time and frequency across the Australian continent via an optical fibre network. This network will meet the needs of future telecommunications, science and astronomy projects including the Australian bid for the Square Kilometre Array radio-astronomy project.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100141
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
High sensitivity and precision mass spectrometry for tracing Australia's ancient evolution and securing our future groundwater resources. High sensitivity and precision mass spectrometry for tracing Australia’s ancient evolution and securing our future groundwater resources: Micro-sampling thermal ionisation mass spectrometry (TIMS) provides the ability to undertake ultra low-level isotope analysis of earth and environmental samples. Analysis of radiogenic (for example, Neodymium, Strontium and ....High sensitivity and precision mass spectrometry for tracing Australia's ancient evolution and securing our future groundwater resources. High sensitivity and precision mass spectrometry for tracing Australia’s ancient evolution and securing our future groundwater resources: Micro-sampling thermal ionisation mass spectrometry (TIMS) provides the ability to undertake ultra low-level isotope analysis of earth and environmental samples. Analysis of radiogenic (for example, Neodymium, Strontium and Lead) and stable (for example, Boron) isotopes allows researchers to trace the evolution of the Australian continent from its beginnings in the Precambrian through to the impacts of climate change in the Quaternary period (the last 2.6 million years). The proposed micro-sampling TIMS facility will give researchers the opportunity to characterise mineral deposit formation, paleoclimate records and groundwater sources with new levels of accuracy and precision. This will help secure the economic and environmental future of Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100183
Funder
Australian Research Council
Funding Amount
$715,000.00
Summary
An ICP-ToF-MS facility for environmental, mineral and biological science. This project aims at establishing a facility for the detection, quantification and rapid mapping of elements and their isotopes in nanoparticles and a diverse set of biological and earth materials. The facility consists of a latest generation ICP-ToF-MS that can simultaneously collect a full suite of isotopic information (Li to U) from liquid samples or, in combination with laser ablation and laser induced breakdown spectr ....An ICP-ToF-MS facility for environmental, mineral and biological science. This project aims at establishing a facility for the detection, quantification and rapid mapping of elements and their isotopes in nanoparticles and a diverse set of biological and earth materials. The facility consists of a latest generation ICP-ToF-MS that can simultaneously collect a full suite of isotopic information (Li to U) from liquid samples or, in combination with laser ablation and laser induced breakdown spectroscopy, solid samples. It will enhance capabilities and sample throughput in environmental science, geoscience, biology and cultural heritage research, significantly accelerating the discovery of new ore bodies, improving environmental risk assessment and assisting research in cancer biology.Read moreRead less