From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilit ....Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilities, and released for community use. These developments underpin future ocean state forecasts, sea ice forecasts, wave forecasts, decadal climate prediction and climate process studies. The project will benefit search and rescue, Defence and shipping operations, and will enhance future climate projections.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100094
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnit ....The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnitude improvement in the clarity of our view of this central component of the Galaxy. The project also aims to enable Mopra to serve as a key element in the Australian Long Baseline Array. The project aims to ensure Australian involvement in three grand design international endeavours.Read moreRead less
Multi-model predictions of ecosystem flux under climate change based on novel genetic and image analysis methods. Improving the forecasts of ecosystem shifts must be a key focus of future ecological research if we are to preserve our unique Australian landscapes. Our proposal is of clear benefit to Australia because of the urgent need for integrated methods to predict the cumulative impact of shifts in climate and land use. We will also contribute innovative tools involving genetic and image ana ....Multi-model predictions of ecosystem flux under climate change based on novel genetic and image analysis methods. Improving the forecasts of ecosystem shifts must be a key focus of future ecological research if we are to preserve our unique Australian landscapes. Our proposal is of clear benefit to Australia because of the urgent need for integrated methods to predict the cumulative impact of shifts in climate and land use. We will also contribute innovative tools involving genetic and image analysis, and state-of-the-art modelling. The damage modern human societies are inflicting on global environments has led to a great demand for logistically feasible and cost-effective ways to prevent biodiversity loss.Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ....ARC Molecular and Materials Structure Research Network. The Network will build powerful e-Science resources for the structural sciences. Collaborative remote access will be developed for sophisticated instrumentation, including instruments planned for the Replacement Research Reactor and Australian Synchrotron. A structure database service with cross disciplinary content and versatile visualisation and analysis capabilities will further exemplify smart information use. The internet services will ultimately harness the Grid, enabling linkage into other national and international Grid systems. Encompassing physics, computer science, applied mathematics, chemistry and biochemistry, and catalysing interaction across these disciplines, the MMSN will impact all five National Research Priority 3 goals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100141
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality c ....High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality changes, pollution histories, recent geomorphological change, land-use change, introduction of invasive species and the occurrence of bushfires. A better understanding of the occurrence and timing of these major environmental issues is of national and regional importance.Read moreRead less
Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent ....Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent research breakthroughs, including novel datasets derived from satellite and field observations. The outcomes are expected to quantify sea ice retreat due to ocean waves for the first time, with potentially major implications for coupled wave–sea ice modelling in climate studies.Read moreRead less