Rapid method development in pharmaceutical analysis using quality-by-design principles. Chemical analysis using separation methods underpins all stages of drug design and analysis. This project will generate new approaches to greatly reduce the time taken to develop a new method of analysis. This will be achieved through development of new computerised techniques for rapid screening, selection and optimisation of analytical methods.
Fragment based screening to deliver drugs targeting tuberculosis and the gametocyte and liver stages of Plasmodium. This project will identify natural products that bind to critical proteins in malaria and tuberculosis to discover new ways to treat these diseases.
Fostering Aboriginal sexual well-being by building on strengths. This project aims to use a strengths-based approach to examine how Aboriginal young people draw on social, cultural and personal resources to build their sexual well-being. Many Aboriginal Australians see strengths approaches as essential to addressing disadvantage. However, to date they have not been widely used to address the significant sexual health inequalities experienced by Aboriginal young people. The project will create ne ....Fostering Aboriginal sexual well-being by building on strengths. This project aims to use a strengths-based approach to examine how Aboriginal young people draw on social, cultural and personal resources to build their sexual well-being. Many Aboriginal Australians see strengths approaches as essential to addressing disadvantage. However, to date they have not been widely used to address the significant sexual health inequalities experienced by Aboriginal young people. The project will create new knowledge about ‘what works’ in supporting the sexual well-being of Aboriginal young people, that has relevance to a broad range of disciplines beyond the area of health and well-being.Read moreRead less
Doubly disadvantaged: harnessing elements of resilience and establishing information for systems change. Aboriginal children with a disability who receive insufficient support when young are likely to experience a lifetime of disadvantage. This project will provide these children, their families and their carers with a culturally appropriate, holistic pathway enabling easier access to health, social, and educational services.
Zirconium alloying and grain refinement of magnesium alloys with ZirCAST. Zirconium alloying and grain refinement is a key issue restricting the commercial production of value-added zirconium-containing magnesium alloys for use in the automotive industry. This 3-year linkage program builds on the applicants' invention of a proprietary grain refiner ZirCAST, and is undertaken to investigate the major fundamental aspects of zirconium alloying and grain refinement with ZirCAST. In addition to an ex ....Zirconium alloying and grain refinement of magnesium alloys with ZirCAST. Zirconium alloying and grain refinement is a key issue restricting the commercial production of value-added zirconium-containing magnesium alloys for use in the automotive industry. This 3-year linkage program builds on the applicants' invention of a proprietary grain refiner ZirCAST, and is undertaken to investigate the major fundamental aspects of zirconium alloying and grain refinement with ZirCAST. In addition to an excellent postgraduate training environment, it aims to provide and develop, in partnership with industry, optimum zirconium alloying and grain refinement technology with ZirCAST and enhance Australia's leading global position in this strategically and commercially important area.Read moreRead less
Assessing the effectiveness, acceptability and sustainability of a culturally adapted evidence-based intervention for Indigenous parents. This project will explore a partnership model for capacity building in Indigenous child protection services. It will also evaluate the effectiveness, acceptability and sustainability of a culturally adapted evidence-based parenting program designed to reduce family risk factors and child behavioural and emotional problems in Indigenous families.
Social auditing for positive change and indigenous life-world experiences in the resource rich Pilbara. Roebourne is an impoverished Indigenous community in the heart of the booming resource industries of the Pilbara. The town symbolises the challenges and opportunities for contemporary Australia. This project has been initiated by the Ngarluma and Yjindibarndi Peoples and will be co-funded and directed by these Peoples. The Project will adapt and extend approaches developed by Indigenous commun ....Social auditing for positive change and indigenous life-world experiences in the resource rich Pilbara. Roebourne is an impoverished Indigenous community in the heart of the booming resource industries of the Pilbara. The town symbolises the challenges and opportunities for contemporary Australia. This project has been initiated by the Ngarluma and Yjindibarndi Peoples and will be co-funded and directed by these Peoples. The Project will adapt and extend approaches developed by Indigenous communities in Canada to record the needs, hopes and ambitions of the people of the Roebourne region and in doing so document their solutions to real and significant problems. The project does not just enable consultation with an Indigenous community rather it helps create a platform for that community, if it chooses, to make decisions for the future.Read moreRead less
Pulsed oscillating mass analyser. Mass spectrometers are ubiquitous components in chemical analysis, but are often large and expensive. We have developed a new method for mass analysis, which is smaller and cheaper than existing technology. However, the analyser needs further research to determine whether it has the performance specifications to match the other technologies. The objective of this research is to characterise, explore and extend the prototype and to develop the appropriate math ....Pulsed oscillating mass analyser. Mass spectrometers are ubiquitous components in chemical analysis, but are often large and expensive. We have developed a new method for mass analysis, which is smaller and cheaper than existing technology. However, the analyser needs further research to determine whether it has the performance specifications to match the other technologies. The objective of this research is to characterise, explore and extend the prototype and to develop the appropriate mathematical algorithm for mass analysis. Success in this project may lead to a new mass analyser that can be incorporated into analytical instruments, many of which are manufactured in Australia.Read moreRead less
Nanostructured films for optical document security. This project aims to develop a new class of synthetic thin films, with unique optical signatures as strong anti-counterfeiting features for future generations of Australian banknotes. The project expects to produce novel, ultra-thin films patterned on the nanoscale that produce vivid, easily recognisable optical effects building on recent advances in nanophotonic optical design and scalable nanofabrication strategies. The development of a range ....Nanostructured films for optical document security. This project aims to develop a new class of synthetic thin films, with unique optical signatures as strong anti-counterfeiting features for future generations of Australian banknotes. The project expects to produce novel, ultra-thin films patterned on the nanoscale that produce vivid, easily recognisable optical effects building on recent advances in nanophotonic optical design and scalable nanofabrication strategies. The development of a range of optical security features in Australia will ensure long-term confidence in our currency. An outcome of the project could be the commercialisation of new types of anti-counterfeiting features for use in Australia and overseas.Read moreRead less
Hydrodynamics of Fringing Reef Systems. This project aims to develop a numerical circulation model applicable to fringing reef systems, in particular, the Ningaloo reef, Western Australia. The model will include the effects of tides, winds, surface gravity waves and density. The model results will be compared to field measurements collected by the Australian Institute of Marine Science. After the model has been developed and validated, it will be used to investigate processes such as water e ....Hydrodynamics of Fringing Reef Systems. This project aims to develop a numerical circulation model applicable to fringing reef systems, in particular, the Ningaloo reef, Western Australia. The model will include the effects of tides, winds, surface gravity waves and density. The model results will be compared to field measurements collected by the Australian Institute of Marine Science. After the model has been developed and validated, it will be used to investigate processes such as water exchange between lagoons and open sea, effects of contaminant spills and recruitment within the reef systems. An understanding of these processes is essential for the sustainable management of these systems.Read moreRead less