ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989726
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Nanophotonic and Microfluidic Integration Facility: a Platform for Optofluidics. Emerging 'lab on a chip' technology promises to provide low-cost, mass produced platforms for monitoring and processing of environmental and biological samples (eg. water quality and early cancer detection). These essentially fluidic platforms will require integrated photonic components to provide the vast array of optical interrogation options that are used in all modern laboratories. The proposed facility will e ....Nanophotonic and Microfluidic Integration Facility: a Platform for Optofluidics. Emerging 'lab on a chip' technology promises to provide low-cost, mass produced platforms for monitoring and processing of environmental and biological samples (eg. water quality and early cancer detection). These essentially fluidic platforms will require integrated photonic components to provide the vast array of optical interrogation options that are used in all modern laboratories. The proposed facility will enable Australian researchers to effectively integrate nano-photonic structures with engineered micro-fluidics into a single optofluidic chip. This will bring researchers in photonics and microfluidics together and will provide platforms supporting support biomedical and environmental and even fundamental physics projects.Read moreRead less
Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food proces ....Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food processing and cosmetic industries. Successful completion of the project can also strengthen our capacity to participate in new areas of research and positioning Australia at the forefront of bionanotechnology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989471
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Facility for innovation in structural biomaterials engineering. Biomaterials are used in a diverse range of environments that impact on the way that all Australians live. The Facility for Innovation in Structural Biomaterials Engineering will greatly assist researchers to undertake cross-disciplinary projects aimed at improving human health eg. smart materials that assist stem cell therapies for treating deafness and spinal cord injuries, as well the way we live eg. more durable building materia ....Facility for innovation in structural biomaterials engineering. Biomaterials are used in a diverse range of environments that impact on the way that all Australians live. The Facility for Innovation in Structural Biomaterials Engineering will greatly assist researchers to undertake cross-disciplinary projects aimed at improving human health eg. smart materials that assist stem cell therapies for treating deafness and spinal cord injuries, as well the way we live eg. more durable building materials for a sustainable national infrastructure. The facility will help Australia remain at the forefront of these high priority areas and see both individuals and industry benefit from advanced biomaterial products.Read moreRead less
Multifunctional biodegradable nanoparticles for enhanced DNA vaccine delivery. DNA vaccine, which shows better immunological and economic merits than conventional vaccines, suffers clinical failure due to the difficulty of delivering intact DNA molecules to relevant cells. This project seeks to develop smart polymer nanospheres to protect the DNA molecules from premature degradation in order to improve its efficacy.
Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conv ....Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conventional condition. This novel probe provides a key to the successful fabrication of innovative nanophotonic devices including photonic transistors, photonic circuits, high-density data storage disks and drives, nano-motors and biochips, which underpin biotechnology, information technology and optical computing technology.Read moreRead less
A novel spectrum encoding technology using nanoparticles for high-density, high-speed information coding and retrieval. The key-sector in high tech markets has been the photonics industry over the last decade, and it will continue to revolutionise our ways of information storage, processing and transfer for the next 10 to 20 years. The current project of novel spectrum-encoding technology will prove to be the key technological innovation in photonics (one of the National Research Priorities), w ....A novel spectrum encoding technology using nanoparticles for high-density, high-speed information coding and retrieval. The key-sector in high tech markets has been the photonics industry over the last decade, and it will continue to revolutionise our ways of information storage, processing and transfer for the next 10 to 20 years. The current project of novel spectrum-encoding technology will prove to be the key technological innovation in photonics (one of the National Research Priorities), which will not only meet the growing demands of the consumer market, but also continue to drive the industry and create new markets. This is in line with the Priority Goals set by the Minister for Education, Science and Training, as it will put Australia into the unique position in the information age.Read moreRead less
Enhanced drug delivery using nanoparticulate dendrimer vectors. Many drug candidates fail during development because of low and variable absorption after oral administration. This project seeks to investigate the utility of specialised nanometer-sized macromolecules (dendrimers), to facilitate the improved delivery of drug molecules where low aqueous solubility is the principle limitation to drug absorption and will also be explored as vectors to specifically target drugs to intestinal lymphoid ....Enhanced drug delivery using nanoparticulate dendrimer vectors. Many drug candidates fail during development because of low and variable absorption after oral administration. This project seeks to investigate the utility of specialised nanometer-sized macromolecules (dendrimers), to facilitate the improved delivery of drug molecules where low aqueous solubility is the principle limitation to drug absorption and will also be explored as vectors to specifically target drugs to intestinal lymphoid (immune) tissue. This project will link the drug delivery expertise of Monash University with the experience in dendrimer design of the Australian biotechnology company Starpharma to provide concrete delivery solutions for the rapidly expanding biotechnology industry in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100098
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise ....Advanced facility for next generation sustainable energy, biomedical & nano-imaging optical fibre technologies. Remote optical fibre technologies are the way forward for effective and safe monitoring of many industries, and will play a big part in the sustainability of Australia's core oil, gas and alternative energy sectors. They are equally important to health industry applications, particularly in medical and imaging technologies. This facility brings together world-class Australian expertise—from across nine universities—in advanced structured optical fibres, complex fibre diagnostic systems, nanoscale imaging, and environment monitoring, to design and implement the next generation of technologies that will reduce the impact of climate change through reduced energy consumption and vastly improved health diagnostics.Read moreRead less
Characterisation and Stability of Thin Electrowetting Films. Electrowetting is of importance to numerous industrial, biomedical and daily life settings such as microfluidic biopharmaceutical applications, coating technology, electronic displays, optical focusing devices, miniaturised chemical analysis systems for homeland security, etc. The work, aimed at generating an understanding of the complex hydrodynamic and physicochemical processes involved, is fundamental research having generic benefit ....Characterisation and Stability of Thin Electrowetting Films. Electrowetting is of importance to numerous industrial, biomedical and daily life settings such as microfluidic biopharmaceutical applications, coating technology, electronic displays, optical focusing devices, miniaturised chemical analysis systems for homeland security, etc. The work, aimed at generating an understanding of the complex hydrodynamic and physicochemical processes involved, is fundamental research having generic benefits to researchers in interfacial science, electrokinetics and microfluidics. The results will also be beneficial to industrial workers in providing engineering protocols for the development of these devices by identifying optimal conditions for fluid manipulation without prone-to-wear mechanical components. Read moreRead less