One of the main trends in the evolution of the primate brain was the huge expansion of the cortical areas devoted to visual processing. However, the exact role of individual areas remains highly controversial, making detailed physiological and anatomical studies in suitable primate models a key step to elucidating their function in the human brain. In this project, we will address the organization of a poorly known group of visual areas, which is located deep in a part of the brain called the in ....One of the main trends in the evolution of the primate brain was the huge expansion of the cortical areas devoted to visual processing. However, the exact role of individual areas remains highly controversial, making detailed physiological and anatomical studies in suitable primate models a key step to elucidating their function in the human brain. In this project, we will address the organization of a poorly known group of visual areas, which is located deep in a part of the brain called the interhemispheric fissure (the medial complex of visual areas). Preliminary evidence suggests that these areas may provide anatomical shortcuts linking vision, behavioural reactions, and emotion. Suppose, for example, that you are sitting outside reading. Although deep in concentration, you are still able to detect the sudden movement of an approaching object in your peripheral field of vision. In many cases you can react (e.g., by ducking , or raising your arms to protect the face) long before you register what the object actually is. An adrenaline rush often accompanies these quick motor reactions, implying a parallel activation of the autonomic nervous system. While the mechanism by which the brain promotes these quick reactions remains poorly understood, we believe that the medial complex of visual areas holds the key. The aim of this study is to map the anatomical framework underlying our ability to react to sudden stimuli in our peripheral visual field. Such work is fundamental for understanding the functional organization of the brain. It also has the potential to lay the groundwork for developments in areas of applied research, including medicine (e.g. the design of better rehabilitation strategies for people with brain damage) and the cognitive sciences (e.g. a better understanding of the factors that limit human responses to visual stimuli).Read moreRead less
The role of spike patterning in shaping human perception of tactile stimuli. Every touch sensation from our fingertips is conveyed to the brain through the nerves by means of electrical impulses similar to any digital device. Using unique technology developed in our lab we can intercept this neural communication and insert our own messages to test how these signals are interpreted and converted into perceptual experiences. We aim to reveal the rules by which timing of neural signal patterns shap ....The role of spike patterning in shaping human perception of tactile stimuli. Every touch sensation from our fingertips is conveyed to the brain through the nerves by means of electrical impulses similar to any digital device. Using unique technology developed in our lab we can intercept this neural communication and insert our own messages to test how these signals are interpreted and converted into perceptual experiences. We aim to reveal the rules by which timing of neural signal patterns shapes the perception of touch - specifically intensity and frequency of vibration. By recording signals from neurons and by testing human perception, we will learn about neural processing mechanisms. The new knowledge generated about sensory coding will be essential for rendering a virtual sense of touch.Read moreRead less
The encoding of friction by tactile mechanoreceptors - the key to fingertip force control during dexterous object manipulation by humans. Unmatched human ability to control the hand so that brittle objects are gently held without slipping, or being crushed by excessive force rely on sophisticated tactile sense in the fingertips. This project will record and analyse signals which human nerves are sending from fingertip receptors to the brain centres controlling hand actions.
Sensory mechanisms underlying human dexterity in object manipulation. This project aims to understand the sensory mechanisms and biomechanics underlying sensory encoding. Tactile sensory information is crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. This project will record signals from single human tactile receptors using microneurography. By modelling the neural data with skin biomechanical events, this project aims t ....Sensory mechanisms underlying human dexterity in object manipulation. This project aims to understand the sensory mechanisms and biomechanics underlying sensory encoding. Tactile sensory information is crucial for controlling grip forces so that delicate objects are held without slipping, or being crushed by excessive force. This project will record signals from single human tactile receptors using microneurography. By modelling the neural data with skin biomechanical events, this project aims to reveal sensory mechanisms underlying the human ability to manipulate objects and use tools. This research could lead to next generation sensory-controlled prosthetics and robotic manipulators.Read moreRead less