ASPREE is the largest clinical trial ever conducted in Australia and will determine whether daily low dose aspirin prevents disease in healthy older people. The study was well-funded initially but will require additional support to complete the vital final stage of data collection and analysis. This will enable the study to answer important questions about the benefits and risks of aspirin in this age group and its effect on disability free survival.
Development Of A Novel Intervention For Training Stepping Ability To Reduce The Risk Of Falls In Older Adults.
Funder
National Health and Medical Research Council
Funding Amount
$390,393.00
Summary
Stepping is often the last protective option to prevent a fall. This study will first modify and validate an interactive system for training stepping ability in older adults. The system will be also provide the capability of acquiring indeices of stepping ability in the home. We will investigate the effect of an in-home training program using this system on stepping ability and falls risk. Findings will inform future interventions for preventing falls.
Is High-school Screening For Hereditary Haemochromatosis Acceptable And Feasible?
Funder
National Health and Medical Research Council
Funding Amount
$728,573.00
Summary
Hereditary haemochromatosis (HH) is a preventable adult onset genetic iron overload disorder. In this research project we will offer senior high school students the opportunity to be tested for their risk of developing HH. Testing will be by a painless cheek brush test. Using questionnaires and interviews we will assess the psychological impact on the students. We will also assess whether those who are at increased risk of HH take steps to prevent disease.
Improving Vision To Prevent Falls: A Randomized Trial
Funder
National Health and Medical Research Council
Funding Amount
$403,892.00
Summary
More than 30% of older Australians fall over at least once a year. Poor eyesight, another very common problem among older Australians, increases the risk of falling. In fact, recent evidence from the Blue Mountains Eye Study suggests that poor vision is one of the strongest risk factors for falls and fractures yet identied. Our project is designed to assess whether improving vision will decrease the chance of falls and fractures. We will recruit 1200 people aged 75 years and over from among thos ....More than 30% of older Australians fall over at least once a year. Poor eyesight, another very common problem among older Australians, increases the risk of falling. In fact, recent evidence from the Blue Mountains Eye Study suggests that poor vision is one of the strongest risk factors for falls and fractures yet identied. Our project is designed to assess whether improving vision will decrease the chance of falls and fractures. We will recruit 1200 people aged 75 years and over from among those attending community-based aged care services in the inner western suburbs of Sydney. If they consent to participate, people will be randomly allocated to either an intervention or control group. Those in the intervention group will receive a simple, yet comprehensive, series of vision and eye tests. These tests will be done by an optometrist, either in subjects' homes or at the study centre. Our previous research suggests that nearly 50% of subjects will benefit from having new glasses and 10% might require cataract surgery. If necessary, treatment will be paid for from study funds. Some vision problems cannot be fixed. In these cases, an occupational therapist will arrange appropriate home modifications to improve vision-related function. Subjects will be followed-up for 12 months to assess the frequency of falls in the intervention and control groups. We hope to find a 33% reduction in falls in the intervention group. We will follow subjects for a further year to identify fractures.Read moreRead less
Impaired Stepping As A Risk Factor For Falls In Older People
Funder
National Health and Medical Research Council
Funding Amount
$564,727.00
Summary
Stepping is often the last protective option to prevent a fall. This study will investigate stepping responses as a risk factor for falls. Complementary studies of physiological and psychological contributions to stepping will also be conducted. A path model will be used to examine the relative importance of physiological, psychological and behvioural factors. An exercise program to imrpove stepping responses will be trialed. Findings will inform future interventions for preventing falls.
Minimising Disability And Falls In Older People Through A Post-hospital Individualised Exercise Program.
Funder
National Health and Medical Research Council
Funding Amount
$536,435.00
Summary
This study aims to implement and evaluate the Functional Activities for Better Balance (FABB) program, a tailored exercise program which is designed to minimise disability and falls, among older adults who have recently had a hospital stay. A randomised controlled trial will be undertaken to determine the success of the program in minimising disability and falls and improving balance, muscle strength, and reaction time, quality of life and fear of falling. In addition, predictors of adoption of ....This study aims to implement and evaluate the Functional Activities for Better Balance (FABB) program, a tailored exercise program which is designed to minimise disability and falls, among older adults who have recently had a hospital stay. A randomised controlled trial will be undertaken to determine the success of the program in minimising disability and falls and improving balance, muscle strength, and reaction time, quality of life and fear of falling. In addition, predictors of adoption of and adherence to the exercise program and the cost effectiveness of the program will be established. We will recruit 350 older people in the first six months after an in-patient stay in aged care and rehabilitation wards at one of two large teaching hospitals. Participants randomised to the intervention group will be asked to complete an individualised home exercise program three times a week. In addition, they will be offered a choice between receiving monthly physiotherapy home visits or attending exercise classes. These weekly exercise classes will be conducted by physiotherapists and will be made up of 6-8 people. The control group will receive an education booklet about falls prevention and will be given the opportunity to join the program on a self-funding basis after their one-year control period is complete. Post-intervention between-group comparisons will be made using appropriate statistical techniques including regression models. Additional analyses will establish predictors for program adoption and adherence and cost-effectiveness (the incremental cost per fall prevented in the exercise group compared with the control group). This study addresses an increasingly important health care problem in a systematic manner and thus has the potential to substantially enhance the health of older people in Australia and internationally.Read moreRead less
The FREEDOM Study: A RCT Of Sunlight And Calcium To Reduce Vitamin D Deficiency In Older People In Residential Care
Funder
National Health and Medical Research Council
Funding Amount
$838,972.00
Summary
The proposed study emanates from a large ongoing epidemiological study on falls and fractures in the elderly (the FREE study). Falls and fractures are major problems in the elderly. This is the genesis for the FREEDOM (Falls Risk Epidemiology: Effect of vitamin D on skeletal Outcomes and other Measures) intervention study. The FREEDOM study will evaluate the effect of a public health strategy to reduce falls and fractures in older people living in residential care (namely appropriate sun light e ....The proposed study emanates from a large ongoing epidemiological study on falls and fractures in the elderly (the FREE study). Falls and fractures are major problems in the elderly. This is the genesis for the FREEDOM (Falls Risk Epidemiology: Effect of vitamin D on skeletal Outcomes and other Measures) intervention study. The FREEDOM study will evaluate the effect of a public health strategy to reduce falls and fractures in older people living in residential care (namely appropriate sun light exposure and calcium supplementation) in a randomised trial. The primary endpoints of this study will be reduction in falls and change in vitamin D levels. Other endpoints will be change in motor function, mood, bone turnover and fracture incidence. The proposed public health strategy to be examined is readily transferable to routine practice and would have very good feasibility for easy implementation and are generally applicable to the residential care setting, where the study will be conducted. Moreover the proposed approach would be low in cost and does not depend on other health system input. Potentially large numbers of people would benefit from the better understanding of simple methods of securing improved vitamin D status.Read moreRead less
Developing a disability policy model to target the prevention or reduction of limitations on functioning and wellbeing. With the ageing of Australian society the challenge for public health is shifting from preventing death and disease onset to supporting healthy and productive ageing. The disability policy model will allow cost-effective targeting of interventions to reduce or prevent onset of disability or reduce its severity particularly among older Australians.
Are Cardiac Conditions In Older Women Managed Appropriately?
Funder
National Health and Medical Research Council
Funding Amount
$289,492.00
Summary
Cardiac conditions, including heart attach, heart failure, angina and high blood pressure are very common among older Australians. They account for large proportions of deaths, morbidity and health care costs. For most of these conditions there are highly effective treatments, however there is evidence that these are not as well used as they should be. Also, for women, diagnosis may be delayed due to perceptions that heart disease is a problem mainly among men. The project is based on the Austra ....Cardiac conditions, including heart attach, heart failure, angina and high blood pressure are very common among older Australians. They account for large proportions of deaths, morbidity and health care costs. For most of these conditions there are highly effective treatments, however there is evidence that these are not as well used as they should be. Also, for women, diagnosis may be delayed due to perceptions that heart disease is a problem mainly among men. The project is based on the Australian Longitudinal Study on Women's Health which includes more than 10,000 women, over half living in rural and remote areas. Women with cardiac conditions will be surveyed about their medical care. This information, together with data they have provided over the last 6 years (and Medicare data if the women have given their consent), will be compared with best practice guidelines established by NHMRC and the Heart Foundation. In this way the project will examine the adequacy of medical care among older women in sufficient detail to make actionable recommendations to health authorities for where improvements are needed.Read moreRead less