Monomeric C-reactive Protein As Pathogenic Factor And Therapeutic Target In Athero-thrombotic Disease.
Funder
National Health and Medical Research Council
Funding Amount
$86,570.00
Summary
Vascular disease of the heart, brain and limbs affects many people in Australia and throughout the world. Current treatments assist in slowing the development and progression of established disease, but new developments are required. This project will investigate the role of C-reactive protein in vascular disease and evaluate its potential as a new therapeutic target in the future.
EFFECT OF LIPOXIN A4 AND PROSTAGLANDIN E2 IN ASSISSTED BONE HEALING
Funder
National Health and Medical Research Council
Funding Amount
$118,796.00
Summary
Bone healing and repair following trauma involves a complex series of events at both the cellular and molecular levels. This study aims to determine that local application of optimal dose of lipoxin A4 (promote resolution of inflammation) and prostaglandin E2 (low dosage stimulating localised bone formation) will promote healing following the placement of polymer foam in the defect, there by develop a therapy where bone deposition is accelerated and healing is enhanced.