Magnetic Seizure Therapy:The Neural Correlates And Neurocognitive Outcomes Of A Novel Therapeutic Approach To Depression
Funder
National Health and Medical Research Council
Funding Amount
$231,147.00
Summary
Depression is a substantial clinical problem for which ECT is the most efficacious treatment. However, ECT has cognitive side-effects which limit its applicability and acceptance by patients. The development of a new treatment with similar efficacy but which minimizes these side effects would have great clinical value. One promising possibility is magnetic seizure therapy (MST). This project will investigate the neurological outcomes of MST in depression, focusing on the cognitive outcomes.
Cellular And Molecular Determinants Of Preleukaemic And Leukaemic Stem Cells
Funder
National Health and Medical Research Council
Funding Amount
$292,635.00
Summary
It has recently become evident that the formation, growth and relapse of many cancers is driven by a rare population of cancer stem cells (CSCs) that have the unique ability to propagate new tumours and are highly resistant to current therapies. However, which normal cells are transformed into CSCs is not known. We will take a potent cancer gene found in leukaemia, and switch it on and off in specific blood cells in mice to determine which healthy cells can be turned into leukaemic stem cells.
Effects Of Resveratrol On Obesity In Non-human Primates
Funder
National Health and Medical Research Council
Funding Amount
$328,992.00
Summary
My research area is pharmacology focussing on drug metabolism in ageing. Drugs work differently in older people. By understanding why this is treatment can be optimised for older adults. This research will investigate the mechanism of action of resveratrol a dietary supplement on reducing diet-induced obesity and how it can be applied to ageing. Better understanding of resveratrol will lead to new approaches for treating obesity-related disorders and ageing diseases to improve quality of life an ....My research area is pharmacology focussing on drug metabolism in ageing. Drugs work differently in older people. By understanding why this is treatment can be optimised for older adults. This research will investigate the mechanism of action of resveratrol a dietary supplement on reducing diet-induced obesity and how it can be applied to ageing. Better understanding of resveratrol will lead to new approaches for treating obesity-related disorders and ageing diseases to improve quality of life and reduce healthcare costs.Read moreRead less