Home Based Rehabilitation To Reduce Falls And Disability In Parkinson Disease.
Funder
National Health and Medical Research Council
Funding Amount
$805,599.00
Summary
Falls occur in more than half of the 80,000 Australians living with Parkinson disease. This research will examine the extent to which a program of home rehabilitation using exercises, movement strategies and falls education is effective in reducing the number of falls, the injuries from falls and disability. We will also examine the effects of home based rehabilitation on quality of life. We shall compare the outcomes of the integrated rehabilitation home program with a life-skills program.
Cellular Effects Of Glucocerebrosidase (GBA) Mutations In Lewy Body Diseases
Funder
National Health and Medical Research Council
Funding Amount
$524,820.00
Summary
Approximately 1 in 100 people are carriers of mutations in the glucocerebrosidase (GBA) gene and are at considerably greater risk of diseases characterised clinically by parkinsonism and by the presence of Lewy body-related pathology. This study will provide tissue-based evidence of the cellular lipid and protein changes relating to Lewy body formation in patients with GBA mutations, providing the information necessary to identify the pathways and mechanisms involved.