A Parent Education And Skills Training Intervention For Young Adolescents With Autism
Funder
National Health and Medical Research Council
Funding Amount
$436,500.00
Summary
Autism is a most severe and prevalent lifelong developmental disorder affecting approximately one in every thousand children and their families. Autism is associated with personal suffering and is a significant burden and stress for parents, families and carers and cost to the community. In earlier work we have demonstrated that providing a structured program of parent education and guidance to families with preschool children with autism leads to improved parental adjustment and mental health. ....Autism is a most severe and prevalent lifelong developmental disorder affecting approximately one in every thousand children and their families. Autism is associated with personal suffering and is a significant burden and stress for parents, families and carers and cost to the community. In earlier work we have demonstrated that providing a structured program of parent education and guidance to families with preschool children with autism leads to improved parental adjustment and mental health. The program also led to behavioural and developmental benefits for the child. The early secondary school years bring further stress and difficulty to adolescents with autism and their families. This project aims to assess the effectiveness of a parent education and training program for parents with autistic adolescents aged 12-14 years. If shown to be effective, this manual based intervention can be readily used by professionals to promote parent mental health, family adjustment and improve the wellbeing and outcome for adolescents with autism. As a result, family stress and the necessity of out of home care may be reduced and school participation improved.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100040
Funder
Australian Research Council
Funding Amount
$442,302.00
Summary
Quality Assurance of Mobile Applications by Effective Testing and Repair. This project aims to create advanced techniques that will enable software engineers to effectively develop quality assured and robust software systems. This project expects to generate new and innovative approaches that automate software testing and repair. The expected outcomes of this project include new knowledge of software engineering, development of an automated and cost-effective testing system with improved coverag ....Quality Assurance of Mobile Applications by Effective Testing and Repair. This project aims to create advanced techniques that will enable software engineers to effectively develop quality assured and robust software systems. This project expects to generate new and innovative approaches that automate software testing and repair. The expected outcomes of this project include new knowledge of software engineering, development of an automated and cost-effective testing system with improved coverage, greater bug detection and repair, and faster testing protocols. This should provide significant benefits to software users by providing reliable and user-friendly systems and to software companies to position Australia as a global leader in software development and technological advancement.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Developing And Evaluating A Multimodal Antibiotic Allergy Strategy To Improve Antimicrobial Stewardship In High-risk Antibiotic Usage Populations
Funder
National Health and Medical Research Council
Funding Amount
$303,014.00
Summary
Antibiotic allergies lead to the use of inferior antibiotics and generation of “superbugs”. Antibiotic allergy testing removes up to 90% of allergies, although remains unavailable to many and unreliable in some severe antibiotic reactions. We aim to validate antibiotic allergy bedside tools and programs, and develop laboratory tests that can diagnose and prevent severe antibiotic allergies, to improve appropriate antibiotic prescribing and patient outcomes.
An Exploration Of Functional Decline And The Potential For Rehab In Patients With Advanced Non-small Cell Lung Cancer
Funder
National Health and Medical Research Council
Funding Amount
$50,000.00
Summary
Lung cancer is one of the commonest human cancers and the leading cause of cancer deaths. People with advanced cancer experience significant decline in functional capacity as their disease advances and they approach death. This decline is likely to have significant impact on quality of life. In lung cancer this decline can be exacerbated by chronic illnesses such as chronic obstructive pulmonary disease (COPD). While significant clinical benefits have been demonstrated in COPD patients with the ....Lung cancer is one of the commonest human cancers and the leading cause of cancer deaths. People with advanced cancer experience significant decline in functional capacity as their disease advances and they approach death. This decline is likely to have significant impact on quality of life. In lung cancer this decline can be exacerbated by chronic illnesses such as chronic obstructive pulmonary disease (COPD). While significant clinical benefits have been demonstrated in COPD patients with the introduction of pulmonary rehabilitation, little research has been conducted to either map the functional status of lung cancer patients or to explore the application of pulmonary rehabilitation in this setting. This study seeks to begin a program of work in this area through first exploring the characteristics of functional decline in this group and then assessing the feasibility and acceptability of a rehabilitation program specifically addressing the functional status needs identified.Read moreRead less
A Population-based Longitudinal Assessment Of Early Life Vitamin D And Risk Of Food Allergy
Funder
National Health and Medical Research Council
Funding Amount
$466,086.00
Summary
There has been a dramatic and unexplained increase in food allergy over recent decades. The increase in food allergy may relate to a concordant increase in early vitamin D insufficiency, however this hypothesis has never been directly tested. This project will use existing/funded samples from two NHMRC funded studies to conduct a detailed investigation of (i) the determinant and predictors of early life vitamin D insufficiency; and (ii) the association of vitamin D insufficiency and food allergy ....There has been a dramatic and unexplained increase in food allergy over recent decades. The increase in food allergy may relate to a concordant increase in early vitamin D insufficiency, however this hypothesis has never been directly tested. This project will use existing/funded samples from two NHMRC funded studies to conduct a detailed investigation of (i) the determinant and predictors of early life vitamin D insufficiency; and (ii) the association of vitamin D insufficiency and food allergy.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100473
Funder
Australian Research Council
Funding Amount
$410,154.00
Summary
Effective integration of human and automated analyses for security testing. This DECRA project aims to significantly improve the performance of current state-of-the-art automated security testing approaches, enabling them to discover more security bugs in strict time constraints. The key innovation of the project is its novel way to embrace human element to leverage the ingenuity of the developers. This project will help companies improve the security and reliability of their products, thwarting ....Effective integration of human and automated analyses for security testing. This DECRA project aims to significantly improve the performance of current state-of-the-art automated security testing approaches, enabling them to discover more security bugs in strict time constraints. The key innovation of the project is its novel way to embrace human element to leverage the ingenuity of the developers. This project will help companies improve the security and reliability of their products, thwarting cyberattacks that cost Australian business $29 billion each year. The knowledge from this project will be transferred and integrated into higher education subjects to train the next generations of software developers, who are responsible to build security-critical systems that we all rely on now and in the future.Read moreRead less
The Long-term Consequences Of Assisted Reproduction On The Growth, Metabolic, Respiratory, Psychological, Immunological And Reproductive Development Of The Offspring.
Funder
National Health and Medical Research Council
Funding Amount
$1,552,096.00
Summary
1 in 25 children are born from IVF treatment - incredibly- to our shame; no data exists as to the long-term health of these children. Presented is a unique opportunity, which would be exceedingly difficult to replicate elsewhere in the world, to determine the long-term consequences of IVF upon the development of the offspring, by comparing their growth, metabolic, respiratory, psychological, immunological and reproductive development to a representative sample of WA children- the Raine cohort.
Use Of Analgesics To Reduce Agitation And Agression In Older Persons With Dementia
Funder
National Health and Medical Research Council
Funding Amount
$552,556.00
Summary
Understanding the causes of Behavioural and Psychological Symptoms of Dementia (BPSD) provides a potentially remedial target for interventions. The current study will undertake the first ever trial of analgesics to reduce the frequency of agitation/aggression and other BPSD. By completion we will have new insights into the relationship between pain and various sub-types of BPSD and robust evidence on the best class of analgesics to treat BPSD
Implementation Of A New, Inexpensive And High-throughput Matrix Assisted Laser Desorption / Ionization _ Time Of Flight Mass Spectrometry Test For Superior Detection Of Fragile X Syndrome In Targeted Diagnostics And Newborn Population Screening.
Funder
National Health and Medical Research Council
Funding Amount
$254,175.00
Summary
Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment int ....Background: The Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability. There are now a number of treatments for FXS. However, often this disorder is not clearly recognized. We have developed a novel FXS test that could resolve this issue. Our objective is to develop a commercial package that describes suitability of our test for diagnostic use. If successful this could potentially leading to improvement in the prognosis for FXS children through early treatment intervention.Read moreRead less