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Developing Youth-centred Health Promotion Strategies To Prevent And Mitigate The Adverse Health Impacts Of Adolescent Pregnancy In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$702,235.00
Summary
Adolescent pregnancy is a major public health concern in Papua New Guinea, the Asia-Pacific region, and other low and middle income countries, with severe health and socio-economic outcomes for young women. This three-year qualitative study will examine the experiences of early pregnancy among young Papua New Guineans (15-24 years). Project outcomes will include the design of youth health services and community-outreach programs to curb the ongoing harm associated with adolescent pregnancy.
Enhancing Clinical Management Of Paediatric Malaria In Endemic Areas With Transmission Of Multiple Plasmodium Species
Funder
National Health and Medical Research Council
Funding Amount
$867,511.00
Summary
Malaria remains a major problem for children in developing countries especially where different types of the disease are common. This set of complementary studies, based at an established research site in PNG aims to develop new treatment strategies for childhood malaria. A novel method of giving medicine via a spray under the tongue for sick children before arrival at hospital and modified dosing schedules of an old drug used for treating parasites hidden in the liver will be studied.
Field-based Evaluation Of A Novel Magneto-optical Technique To Diagnose Malaria
Funder
National Health and Medical Research Council
Funding Amount
$637,411.00
Summary
Highly sensitive and low-cost and rapid malaria diagnosis is crucial for renewed efforts to eliminate the disease. We have developed a magneto-optic technique that can diagnose the presence of malaria parasites in blood samples within minutes, with a sensitivity approaching that of high-tech molecular methods that are not applicable at point of care. Here we propose to take this method from the laboratory to clinical settings in malaria endemic countries to directly evaluate its performance.
Unravelling Plasmodium Vivax Transmission To Anopheles Mosquitoes: Role Of Naturally Acquired Transmission Blocking Immunity And Efficacy Of Novel Vaccine And Drug Candidates
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
This project is aimed at better understanding transmission of P. vivax, the world’s most widely spread malaria parasite. Using a newly established experimental platform that enables us to feed P. vivax infected blood to Anopheles farauti mosquitoes, we can start researching factors in human blood that determine P. vivax infection success, test new vaccine and drug candidates for their ability to block transmission and thus significantly advance science surrounding this neglected parasite.
Fundamental Advancement Of Knowledge Of Plasmodium Vivax Biology, Drug Susceptibility And Transmission
Funder
National Health and Medical Research Council
Funding Amount
$316,067.00
Summary
Plasmodium vivax is the most widespread malaria parasite causing over 80 million cases per year. Yet, current means to counter this parasite are grossly inadequate. Vast knowledge gaps exist due to unavailability of continuous cultures, high throughput drug assays and the poor understanding of transmission. This inhibits the development of new treatments for P. vivax. This project will fundamentally advance knowledge of the biology and epidemiology of this important, but neglected pathogen.
Point-of-care HPV-DNA Testing For Cervical Cancer Screening In High-burden, Low-resource Settings
Funder
National Health and Medical Research Council
Funding Amount
$891,184.00
Summary
We will undertake the first field evaluation of a novel, newly-available, easy to use, and highly accurate point-of-care (POC) test for high-risk human papillomavirus (hrHPV) infection that will allow trained health staff to identify women at increased risk of cervical cancer and to provide same-day cervical cryotherapy for pre-cancer lesions identified on clinical examination.
Understanding The Socio-cultural Dimensions Of Tuberculosis In Papua New Guinea: Knowledge To Optimise Public Health Solutions
Funder
National Health and Medical Research Council
Funding Amount
$727,410.00
Summary
Papua New Guinea has among the highest TB incidence rates in the world, with rates in particular areas considerably higher. This three-year qualitative study will examine the socio-cultural contexts of TB control programs. The project outcome will be better contextualised solutions to improve the effectiveness of TB control programs and therefore the spread of TB and its drug resistant forms.
The Impact Of Male Circumcision And Penile Modification Practices On Women In Papua New Guinea, Including Women's Risk Of HIV Transmission.
Funder
National Health and Medical Research Council
Funding Amount
$95,313.00
Summary
This grounded theory study will investigate the impact of male circumcision and penile modification practices on women in PNG, including women�s risk of HIV. The study aims to describe women�s understanding and experience of male circumcision and penile modifications and the processes they use to manage the outcomes of male circumcision. Implications for national HIV policy in Papua New Guinea will be identified. This study will be supported by researchers in Papua New Guinea and Australia.
Mapping Plasmodium Falciparum Population Structure And The Source Of Outbreaks In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$534,786.00
Summary
Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effec ....Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effective.Read moreRead less