Mechanisms and modelling of gels for protein separation. Gradipore approached Sydney University to collaborate on fundamental science needed to improve polymer gels for separation and characterization of proteins. These gels have many applications: e.g. proteomics and diagnostics. Presently, control of polymer microstructure in the synthesis of these gels is by trial and error. This project will create an accurate model of the process so pore size can be predicted. This involves novel work in ex ....Mechanisms and modelling of gels for protein separation. Gradipore approached Sydney University to collaborate on fundamental science needed to improve polymer gels for separation and characterization of proteins. These gels have many applications: e.g. proteomics and diagnostics. Presently, control of polymer microstructure in the synthesis of these gels is by trial and error. This project will create an accurate model of the process so pore size can be predicted. This involves novel work in experimental and theoretical methods developed by the Sydney University group. The result will be qualitative and quantitative understanding which can be subsequently used to tailor-make gels for new applications.Read moreRead less
STABILISATION OF TITANIA PIGMENTS FOR IMPROVED WATER-BASED PAINT APPLICATIONS. This project aims to improve the stability and optical properties of titania pigments in water-based paints. Tailored dispersing agents will be used to stabilise pigments in paints in both the wet and dry state. Enhanced understanding of the dispersing agents interaction with the titania pigment surface and the subsequent stability of the pigment in dry paint films will allow advances in water-based paint stability. T ....STABILISATION OF TITANIA PIGMENTS FOR IMPROVED WATER-BASED PAINT APPLICATIONS. This project aims to improve the stability and optical properties of titania pigments in water-based paints. Tailored dispersing agents will be used to stabilise pigments in paints in both the wet and dry state. Enhanced understanding of the dispersing agents interaction with the titania pigment surface and the subsequent stability of the pigment in dry paint films will allow advances in water-based paint stability. This understanding facilitates continued movement away from solvent-based paints required by environmental and health legislation. The potential growth in market share for the Australian pigment industry is in excess of $50M pa.Read moreRead less
Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials fo ....Development of High Performance Nanocomposite Filtration Membranes: Fabrication and Fouling Mechanisms. This project will develop high performance membranes for the filtration of water and wastewater using novel nanotechnology processes. This will reduce the costs and environmental impact of water treatment and risk from low-level chemical contaminants such as micropollutants. The project will also provide an enhanced technology base for producing low cost, hybrid inorganic-organic materials for widespread environmental, agricultural and food applications.Read moreRead less
An innovative approach to fabricate thermally stable polymer/layered silicate nanocomposites. By fully taking advantage of excellent affinity of water with polar layered silicate and polar polymer, an innovative approach to fabricate thermally stable polymer/layered silicate nanocomposites via melt extrusion with the aid of water/water vapour will be developed. In this process, the pristine layered silicate will be directly exfoliated into individual layers with nanometer thickness and high aspe ....An innovative approach to fabricate thermally stable polymer/layered silicate nanocomposites. By fully taking advantage of excellent affinity of water with polar layered silicate and polar polymer, an innovative approach to fabricate thermally stable polymer/layered silicate nanocomposites via melt extrusion with the aid of water/water vapour will be developed. In this process, the pristine layered silicate will be directly exfoliated into individual layers with nanometer thickness and high aspect ratio, and uniformly dispersed in a polymer matrix. This novel approach is environmentally benign and cost-effective since no alkyl ammonium surfactants are required. The resultant nanocomposites will exhibit excellent barrier properties, high thermal stability, environmental durability and superior mechanical properties. These qualities make them very attractive for many applications in the automotive and packaging industries.Read moreRead less
Switchable interfaces. The discovery project will challenge some of the most demanding issues regarding adhesion and molecular separation: - Surfaces that can release/prevent bio-film formation can provide novel solutions for corrosion-protection, implants, anti-fouling in medical devices as well as in industrial piping and reactors. - Materials for separation on the molecular level, which can bring new possibilities for fast and selective processes to the pharmaceutical industry. The novel comb ....Switchable interfaces. The discovery project will challenge some of the most demanding issues regarding adhesion and molecular separation: - Surfaces that can release/prevent bio-film formation can provide novel solutions for corrosion-protection, implants, anti-fouling in medical devices as well as in industrial piping and reactors. - Materials for separation on the molecular level, which can bring new possibilities for fast and selective processes to the pharmaceutical industry. The novel combination of the two materials research fields - plasma-polymerisation and electroactive materials- will lead to an international capability at the forefront of separation and adhesion research.Read moreRead less
The effect of de-gassing on the dispersion and stability of emulsions and colloidal solutions. Although it is widely accepted that oil and water will not mix, the reverse has recently been found to occur (by the applicant) under the unusual conditions of complete de-gassing. This discovery has opened up new areas for investigation and for the development of new processes and products. Hydrocarbon oils and hydrophobic powders can now be readily dispersed in water without the use of additives. Ho ....The effect of de-gassing on the dispersion and stability of emulsions and colloidal solutions. Although it is widely accepted that oil and water will not mix, the reverse has recently been found to occur (by the applicant) under the unusual conditions of complete de-gassing. This discovery has opened up new areas for investigation and for the development of new processes and products. Hydrocarbon oils and hydrophobic powders can now be readily dispersed in water without the use of additives. However, the mechanisms involved have not yet been elucidated and it is the aim of this project to understand the process and develop potential commercial applications.Read moreRead less
Nanogels: Next Generation Polymeric Particles. The existing knowledge in the formation of polymeric networks limits the technological development of polymer materials. This project will introduce new polymeric particles, called nanogels to open a new area in new polymeric architecture research. A number of new structures based on the nanogels will be developed. These new macromolecules will not only bring the polymer science into a new field, it will provide a great opportunity to discover the ....Nanogels: Next Generation Polymeric Particles. The existing knowledge in the formation of polymeric networks limits the technological development of polymer materials. This project will introduce new polymeric particles, called nanogels to open a new area in new polymeric architecture research. A number of new structures based on the nanogels will be developed. These new macromolecules will not only bring the polymer science into a new field, it will provide a great opportunity to discover the next generation of the polymeric products, particularly for application in automotive paint, drug delivery and bio-molecular separations.Read moreRead less
Nanoparticles with designed morphology for surface-coating applications. Significantly improved water-based paints, with zero volatile organic content and organic opacifiers, are highly desirable for environmental and health reasons. The science needed to produce such paints has been persistently elusive. USyd and Dulux will collaborate to achieve these paints by using Australian-developed platform technologies that allow polymer architecture to be controlled at molecular and nanoscale levels. T ....Nanoparticles with designed morphology for surface-coating applications. Significantly improved water-based paints, with zero volatile organic content and organic opacifiers, are highly desirable for environmental and health reasons. The science needed to produce such paints has been persistently elusive. USyd and Dulux will collaborate to achieve these paints by using Australian-developed platform technologies that allow polymer architecture to be controlled at molecular and nanoscale levels. This will give us the means to make structured nanoparticles with morphologies that had been regarded as unachievable, and that are the key to dispensing with harmful ingredients in paints.Read moreRead less
Biodegradable Porous HEMA-Based Polymers: Innovative Strategies for the Design and Tuneable Single-Step Production of a Novel Class of Scaffolds for Tissue Engineering. This project will lead to the development of new biocompatible, biodegradable, porous materials ideally suited to many applications in tissue engineering. These new biomaterials will be relatively inexpensive to manufacture, via simple processes using non-toxic reagents. The key properties of the biomaterials will be controllable ....Biodegradable Porous HEMA-Based Polymers: Innovative Strategies for the Design and Tuneable Single-Step Production of a Novel Class of Scaffolds for Tissue Engineering. This project will lead to the development of new biocompatible, biodegradable, porous materials ideally suited to many applications in tissue engineering. These new biomaterials will be relatively inexpensive to manufacture, via simple processes using non-toxic reagents. The key properties of the biomaterials will be controllable by appropriate choice of starting materials. The availability of these new biomaterials will facilitate future developments in tissue engineering, which will ultimately lead to improved medical outcomes in areas as diverse as joint and bone repair and organ regeneration. Local manufacture of these biomaterials would also contribute to the development of the Australian biotechnology industry.Read moreRead less
Preparations, Properties, and Applications of New Hydrogels. This project aims to develop a new polymeric matrix system for improved biological separations such as fibrinogen, DNA and RNA. These new hydrogels and membranes will not only be capable of separating biomacromolecules, not possible within the existing systems, but will also develop a new size exclusion type separation system for electrophoresis. The success of the project will have a significant impact in the biotechnology industry. P ....Preparations, Properties, and Applications of New Hydrogels. This project aims to develop a new polymeric matrix system for improved biological separations such as fibrinogen, DNA and RNA. These new hydrogels and membranes will not only be capable of separating biomacromolecules, not possible within the existing systems, but will also develop a new size exclusion type separation system for electrophoresis. The success of the project will have a significant impact in the biotechnology industry. Particularly, it will provide efficient methodologies to fractionate a number of important blood products and strengthen Australian's leading role in this field.Read moreRead less