Designed Delivery - Novel Hydrogels for Drug Delivery from Precisely-Structured Networks. This project will lead to the development of new biodegradable biomaterials ideally suited to many applications in drug delivery and tissue engineering. The understanding of their properties will be built on comprehensive models for diffusion of molecules through the material. The availability of these new biomaterials will facilitate future developments in drug delivery, and will ultimately lead to improve ....Designed Delivery - Novel Hydrogels for Drug Delivery from Precisely-Structured Networks. This project will lead to the development of new biodegradable biomaterials ideally suited to many applications in drug delivery and tissue engineering. The understanding of their properties will be built on comprehensive models for diffusion of molecules through the material. The availability of these new biomaterials will facilitate future developments in drug delivery, and will ultimately lead to improved medical outcomes in many areas such as tissue and bone regeneration. The materials designed in this project will help position the Australian biotechnology and pharmaceutical industries to take advantage of the more than $100B USD market (US alone; growth ~ 10% p.a.) in drug delivery.Read moreRead less
Formation and stability of polymerically stabilized colloids. This project will bring economic, medical and environmental benefits, with improved product performance and manufacturing processes for everyday industrial items relevant to a large industrial sector with significant employment in Australia: inks and paints (for example, surface coatings that can be applied more rapidly without clogging the jets); better means of preventing the fouling of industrial membranes; and improved materials f ....Formation and stability of polymerically stabilized colloids. This project will bring economic, medical and environmental benefits, with improved product performance and manufacturing processes for everyday industrial items relevant to a large industrial sector with significant employment in Australia: inks and paints (for example, surface coatings that can be applied more rapidly without clogging the jets); better means of preventing the fouling of industrial membranes; and improved materials for biomedical applications, with more desirable interactions between living cells and body fluids. These advances will also speed the replacement of solvent-based lacquer paints - detrimental to both environment and user - with water-based products of high quality.Read moreRead less
Microspheres from (Sun)Light – A Sustainable Materials Platform. This project will break new ground in light-induced step-growth precipitation polymerisation techniques for polymer particle formation that do not require any initiator, surfactants, additives or heating, thus constituting an environmentally friendly process. The project will establish the underpinning photochemical particle formation processes and establish a broad monomer base for the production of particles with a wide property ....Microspheres from (Sun)Light – A Sustainable Materials Platform. This project will break new ground in light-induced step-growth precipitation polymerisation techniques for polymer particle formation that do not require any initiator, surfactants, additives or heating, thus constituting an environmentally friendly process. The project will establish the underpinning photochemical particle formation processes and establish a broad monomer base for the production of particles with a wide property profile, including particles with tailored surface properties and the ability to degrade upon a defined trigger signal. Scaling the particles' synthesis, including using Australian sunlight, will enable multi-gram production allowing real-world applications.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347346
Funder
Australian Research Council
Funding Amount
$210,000.00
Summary
Electrochemical Atomic Force Microscope and Nano-Manipulation Facility. This new Facility will add the nano-dimension to the excellent electrochemical mapping facility established at the University of Wollongong over the past 2 years. The instrument we propose to install will allow us to probe electrochemical events and, in particular, the influence of these events on the structure of customised materials at the nano level. This new capability will impact on our research into the development o ....Electrochemical Atomic Force Microscope and Nano-Manipulation Facility. This new Facility will add the nano-dimension to the excellent electrochemical mapping facility established at the University of Wollongong over the past 2 years. The instrument we propose to install will allow us to probe electrochemical events and, in particular, the influence of these events on the structure of customised materials at the nano level. This new capability will impact on our research into the development of efficient artificial muscles, biosensors, corrosion protection coatings, polymeric photovoltaics and new surfaces for mammalian cell culturing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453637
Funder
Australian Research Council
Funding Amount
$256,804.00
Summary
Multi-dimensional polymer characterization facility. The microstructure of polymers dominates their physical properties. This integrated facility will create a world-leading means of characterizing in multiple dimensions the microstructure of complex polymers, eg copolymers and branched polymers. The facility will yield information on the distributions of chain end-groups, monomer microstructure, and branches, as functions of molecular weight. The facility will provide otherwise unobtainable dat ....Multi-dimensional polymer characterization facility. The microstructure of polymers dominates their physical properties. This integrated facility will create a world-leading means of characterizing in multiple dimensions the microstructure of complex polymers, eg copolymers and branched polymers. The facility will yield information on the distributions of chain end-groups, monomer microstructure, and branches, as functions of molecular weight. The facility will provide otherwise unobtainable data for a set of projects exploring questions ranging from how new synthetic materials with tailor-made properties can be created, through to how our understanding of natural polymers can be advanced to improve crop utilization.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560981
Funder
Australian Research Council
Funding Amount
$160,940.00
Summary
Confronting the Challenges in Modern Spectroscopy of Polymers. Polymers and nanocomposites are increasingly being used in new, high value applications as diverse as medicine, structural engineering, optics and electronics. In order to control and understand polymer performance, a detailed knowledge of the chemical structure at all stages in their lifecycle is required - in the liquid, rubber and solid states and during degradation. This application seeks to establish a coordinated Polymer Spectr ....Confronting the Challenges in Modern Spectroscopy of Polymers. Polymers and nanocomposites are increasingly being used in new, high value applications as diverse as medicine, structural engineering, optics and electronics. In order to control and understand polymer performance, a detailed knowledge of the chemical structure at all stages in their lifecycle is required - in the liquid, rubber and solid states and during degradation. This application seeks to establish a coordinated Polymer Spectroscopy Network using new forms of infrared and NMR spectroscopy to probe samples (usually of an non-planar geometry) in a range of configurations. These will be used simultaneously with other techniques such as rheology or thermogravimetry, and will produce capabilities unique in Australia.Read moreRead less
Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine ....Engineered Polymer Scaffolds for Controlled Proliferation and Differentiation of Stem Cells. This project aims to develop a new methodology to sculpt 3D polymer scaffolds coated with cell adhesion and growth factors to control environmental cues, for the first time rapidly generating large quantities of undifferentiated stem cells. This project aims to exponentially increase cell generation in order to finally be able to unlock the potential of stem cells for application in regenerative medicine. The resulting cell repositories could make a significant contribution to human health outcomes.Read moreRead less
A new generation of photoresists for three- dimensional laser lithography. This project aims at a step-change in photoresist technology by introducing visible-light-induced photochemistry as the basis of next generation direct laser writing (DLW) technology. This willenable functional photoresists that allow precision coding of complex soft matter material properties on the three-dimensional nanoscale. The outcomes of the project will enable the mild fabrication of three-dimensional structures w ....A new generation of photoresists for three- dimensional laser lithography. This project aims at a step-change in photoresist technology by introducing visible-light-induced photochemistry as the basis of next generation direct laser writing (DLW) technology. This willenable functional photoresists that allow precision coding of complex soft matter material properties on the three-dimensional nanoscale. The outcomes of the project will enable the mild fabrication of three-dimensional structures with unique property control and resolution, benefitting diverse fields ranging from designer (stem) cell niches and lab-on-a-chip applications to photonic wire bonding.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL170100014
Funder
Australian Research Council
Funding Amount
$3,275,680.00
Summary
Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromo ....Light-Induced chemical modularity: a new frontier in macromolecular design. This project aims to develop powerful light-driven chemistries for the modular construction of advanced macromolecular materials. The expected outcome is a versatile, light-based precision macromolecular synthetic technology platform, enabling critical advances in soft matter material design and synthesis, ranging from selectivity control of chemical reactions and information-coded and biomimetic light-responsive macromolecules to advanced functional photoresists for 3D laser lithography as well as materials that self-report structural transformations by light or are reprogrammable in their properties by photonic fields. Harnessing the power of light as a precision tool for the construction of advanced macromolecular materials will provide technology outcomes for Australian manufacturing industries from electronics to health. This includes laser-driven 3D printing technology at the nano-level, light-adaptive smart reprogrammable coatings and materials, synthetic proteins responsive to light as well as tailor-made single cell niches.Read moreRead less
Special Research Initiatives - Grant ID: SR0354805
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Research Network for Rehabilitation of Structures Using Advanced Materials and Frontier Technologies. There is an urgent need to rehabilitate existing structures that are considered inadequate in strength and serviceability. Frontier strengthening technologies (such as external post-tensioning and plate bonding) using conventional and advanced materials are being currently developed in Australia by different groups, but as yet not in a coordinated manner. The aim of this network is to bring tog ....Research Network for Rehabilitation of Structures Using Advanced Materials and Frontier Technologies. There is an urgent need to rehabilitate existing structures that are considered inadequate in strength and serviceability. Frontier strengthening technologies (such as external post-tensioning and plate bonding) using conventional and advanced materials are being currently developed in Australia by different groups, but as yet not in a coordinated manner. The aim of this network is to bring together a multi-disciplinary team with complementary strengths to provide an integrated solution for rehabilitation of structures. The core of the network focuses on design tools, linking the various technologies to provide appropriate rehabilitation and understanding of life cycle demands for major infrastructure.Read moreRead less