DsbA Foldases From Multidrug Resistant Pathogens As Targets For New Antimicrobials
Funder
National Health and Medical Research Council
Funding Amount
$743,401.00
Summary
Bacteria that cause common human infections, such as cystitis and diarrhoea, are now resistant to many antibiotics. If no action is taken, by 2050 antibiotic resistant infections will kill more people each year than cancer. This project aims to address this global public health crisis by characterising promising new bacterial targets and inhibitors designed to disarm multidrug resistant pathogens. Longer term this work could provide new infection therapies that are urgently needed.
Fall Prevention And Physical Activity Promotion For Older Adults: Cluster Trial Of Effectiveness And Cost-effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$1,291,950.00
Summary
This cluster randomised controlled trial will establish the impact on physical activity and falls of an intervention program that targets both physical activity and falls using assessment, advice and health coaching. The trial will involve 60 established groups of older people, recruited from local chapters of community organisations including Probus, the Older Women’s Network, registered clubs and church groups (estimated average group size of 10; total n = 600).
Active Team – Examining An Online Social Networking Intervention To Increase Physical Activity In Controlled (RCT) And Ecological (ET) Settings
Funder
National Health and Medical Research Council
Funding Amount
$814,041.00
Summary
Lifestyle diseases, such as heart disease and diabetes, are key health problems facing Australia. Effective, low-cost, mass-reach physical activity interventions are urgently needed. This project uses online social networks to deliver an innovative physical activity intervention. This project will determine how effective the software is in changing people’s lifestyle over 12 months, and whether viral marketing techniques can be used to disseminate the program on a mass scale.
The Influence Of Physical Activity And Sedentary Behaviour On Physical Function
Funder
National Health and Medical Research Council
Funding Amount
$1,269,867.00
Summary
Declines in physical function (e.g. stair climbing, bending/kneeling) can lead to a loss of personal independence. Physical activity can prevent or delay these declines, whereas a sedentary lifestyle can hasten them. This project examines the contribution of physical activity and sedentary behaviour to declines in physical function among baby boomers. Results will inform policy aimed at maintaining people’s independence and minimizing health care costs associated with an ageing population.
My Personal Activity Advice – A RCT Investigating The Effectiveness Of Tailored Videos In Promoting Physical Activity Via The Internet
Funder
National Health and Medical Research Council
Funding Amount
$723,190.00
Summary
Only 46% of Australians achieve the recommended 30 minutes of physical activity a day needed to prevent chronic disease, a preventable burden that costs the healthcare system $1.6 billion each year. Web-based interventions can reach most Australians at low cost, but often fail to engage and retain participants long enough to achieve long-term behaviour change. We will evaluate an innovative approach that uses personalised web-based videos provided on a weekly basis that will help Australians bec ....Only 46% of Australians achieve the recommended 30 minutes of physical activity a day needed to prevent chronic disease, a preventable burden that costs the healthcare system $1.6 billion each year. Web-based interventions can reach most Australians at low cost, but often fail to engage and retain participants long enough to achieve long-term behaviour change. We will evaluate an innovative approach that uses personalised web-based videos provided on a weekly basis that will help Australians become more physically active in the long-term.Read moreRead less
Patterns, Pathways And Price Of Developing Disparities In Cardiovascular And Respiratory Health By Age 11-12 Years: The Longitudinal Study Of Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$3,290,912.00
Summary
Cardiovascular and lower respiratory diseases are leading causes of death, show marked social gradients, and have origins in early life. We will measure cardiorespiratory health at age 11-12 years in the national Longitudinal Study of Australian Children. Combined with rich existing psychosocial and health data spanning the entire first decade, we will explore early-life mechanisms underlying emerging patterns of social disparity and their potentially-avoidable cost – evidence that is essential ....Cardiovascular and lower respiratory diseases are leading causes of death, show marked social gradients, and have origins in early life. We will measure cardiorespiratory health at age 11-12 years in the national Longitudinal Study of Australian Children. Combined with rich existing psychosocial and health data spanning the entire first decade, we will explore early-life mechanisms underlying emerging patterns of social disparity and their potentially-avoidable cost – evidence that is essential to develop new intervention strategies.Read moreRead less