Continuity and change in the development of young children with autism. Autism is a severe condition affecting social interaction, communication, behaviour and interests. Parents of children with autism experience high levels of stress associated with the burden of caring. There is a high societal cost associated with the care of people with autism. Research shows outcome in autism is poor, but that early intervention may improve outcome. This project will identify specific early precursors of a ....Continuity and change in the development of young children with autism. Autism is a severe condition affecting social interaction, communication, behaviour and interests. Parents of children with autism experience high levels of stress associated with the burden of caring. There is a high societal cost associated with the care of people with autism. Research shows outcome in autism is poor, but that early intervention may improve outcome. This project will identify specific early precursors of autism which predict outcome. This will allow the development of targeted intervention to give children the best possible start in life and improve longterm outcome. Improvement to the outcome of people with autism will considerably reduce parental and family burden and cost to the community.Read moreRead less
Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide ....Behaviour and emotional problems in young children with developmental delay. This research will provide health professionals, researchers and service providers with a reliable and valid measure to assess behaviour in young children with developmental delay. This will be the first instrument of its kind worldwide. The study will provide the largest and most comprehensive survey of behaviour and emotional problems in young children with developmental delay internationally to date. It will provide information on the types of treatment that are needed for these children and what support is needed for their families. The outcomes of this study have the potential to promote the best possible start in life and long term mental health of this group of at risk and disadvantaged young Australians.Read moreRead less
The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The curr ....The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The current project is directly relevant to the genetics of mental disorders, such as attention deficit hyperactivity (ADHD), that place a large burden, both financially and emotionally, on our society. Understanding the genes and biological pathways that increase risk for mental disorders will ultimately lead to improved treatments for these conditions.Read moreRead less
Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Inc ....Models of adolescent drug use and its consequences. Recent concerns surround the impact of drug abuse - particularly binge drinking, inhalant abuse and cannabis use - on the mental health of adolescents. Early drug use is associated with mental health problems although the mechanisms involved are not well characterised. The present proposal aims to use animal models to characterise substance abuse that occurs during the adolescent period and to investigate its effects on brain and behaviour. Increasing our knowledge of the causes and consequences of adolescent drug abuse will improve Australia's ability to confront this problem and to develop early interventions and treatments that minimise associated harms.Read moreRead less
Genes, neuroanatomy and family process: Predicting adolescent anxiety and depression. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the paucity of developmentally targeted treatment and prevention strategies. This study will provide unique information regarding the risk processes that are operating during early and late adolescence, and will inform us ....Genes, neuroanatomy and family process: Predicting adolescent anxiety and depression. Whilst significant gains in outcomes have been obtained in other areas of health by focusing on early intervention and prevention, in the mental health field this approach has been limited by the paucity of developmentally targeted treatment and prevention strategies. This study will provide unique information regarding the risk processes that are operating during early and late adolescence, and will inform us about how the family environment can act to modulate the impacts of biological vulnerability on risk for mental disorder. This project will contribute to our understanding of who, and what, to target in early intervention and prevention strategies.Read moreRead less
Deakin Family Options: engaging youth with high prevalence mental health problems using family based interventions. Youth depression, anxiety and substance abuse are prevalent, distressing and costly problems impacting one in five young Australians. This collaborative project - called ‘Deakin Family Options’ - will evaluate a family based intervention in order to broaden the therapeutic approaches used for young people and their families.
Studying the effects of repetitive transcranial magnetic stimulation with near Infrared spectroscopy. Repetitive transcranial magnetic stimulation (rTMS) is increasingly being used as a tool in studying human and animal brain function and in the treatment of brain disorders but there are fundamental gaps in our understanding of its basic mechanisms of action and hence our capacity to optimise protocols. This research will use near infrared spectroscopy to study the range of potential ways of alt ....Studying the effects of repetitive transcranial magnetic stimulation with near Infrared spectroscopy. Repetitive transcranial magnetic stimulation (rTMS) is increasingly being used as a tool in studying human and animal brain function and in the treatment of brain disorders but there are fundamental gaps in our understanding of its basic mechanisms of action and hence our capacity to optimise protocols. This research will use near infrared spectroscopy to study the range of potential ways of altering brain activity with rTMS. It will substantially enhance the applicability of the technique ultimately improving our knowledge of human and animal brain function and outcomes for patients with depression and other disorders. It will help reinforce Australia as a leading country in the development of brain stimulation techniques.Read moreRead less
Recognising, assessing, and managing high risk stalking behaviour: An evidence-based approach. Developing effective methods of assessing and treating stalkers will directly impact the health and safety of thousands of stalking victims across Australia, and reduce the number of stalkers coming into contact with the criminal justice system. Application of the assessment and treatment tools developed during this project by mental health and corrective services around Australia will help to reduce p ....Recognising, assessing, and managing high risk stalking behaviour: An evidence-based approach. Developing effective methods of assessing and treating stalkers will directly impact the health and safety of thousands of stalking victims across Australia, and reduce the number of stalkers coming into contact with the criminal justice system. Application of the assessment and treatment tools developed during this project by mental health and corrective services around Australia will help to reduce physical and psychological harm experienced by both stalkers and their victims. The development and implementation of practical and effective strategies that lessen the impact of stalking will reduce the burden of mental ill-health caused by stalking, increase community safety, and reduce overall levels of victimisation in Australian society. Read moreRead less
Poor social functioning in schizophrenia: understanding its causes and developing better treatments. This project will advance knowledge of the thinking processes and the associated neural changes that cause the lifelong social disability which characterises schizophrenia. Findings will, in turn, contribute to better identifying young people, at risk of developing schizophrenia, and inform the design of new interventions and treatments.
Moral reasoning and mental illness: towards a model of moral judgment and moral accountability. This research examines capacities for moral judgment in people with schizophrenia, some of whom act on their delusional beliefs and commit crimes. Findings will, in turn, inform legal and philosophical consideration of the moral accountability of mentally ill defendants, and advance theoretical knowledge of healthy moral decision making.