Structural And Functional Analysis Of A Cancer-linked Co-regulator Complex
Funder
National Health and Medical Research Council
Funding Amount
$729,571.00
Summary
We seek to understand the mechanisms by which genes are switched on and off throughout our lifetime. A number of multi-component protein machines are involved in this process but their make-up and mechanism of action is not understood. We will investigate the structure and function of one of these machines that has been strongly linked to cancer.
Early Career Industry Fellowships - Grant ID: IE230100672
Funder
Australian Research Council
Funding Amount
$470,337.00
Summary
Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure ....Measuring real-time mental workload to improve our Defence capability. This project aims to develop a novel platform for measuring real-time variation in the cognitive workload of humans working with advanced Defence technologies. The project expects to combine innovative statistical techniques with cutting-edge psychological and neuroscience developments to measure and process workload-related brain activity in real-time. Expected outcomes of the project include an enhanced capacity to measure and respond to cognitive workload in the field. This should provide significant benefits such as enhanced performance and safety outcomes, which will provide a strategic advantage to the Australian Defence Force by facilitating the development of advanced technologies that respond to the capabilities of the human user.Read moreRead less
Platelet Glycoprotein Proteolysis: Novel Mechanisms And Risk Factors
Funder
National Health and Medical Research Council
Funding Amount
$441,473.00
Summary
Platelets are the richest source of amyloid precursor protein (APP) in the body. Platelet ADAM10 regulates both the expression and function of the major platelet collagen receptor GPVI, and protective APP processing. Coagulation protein Factor X has a role in activation of ADAM10. This activation is disrupted in blood that has been treated with direct oral anticoagulant (DOAC) rivaroxaban. This grant will investigate the implications for people taking rivaroxaban on regulation of APP and GPVI.
Autonomous Functions for Smart Cars. The aim of this project is to develop autonomous functions for smart cars, such as lane departure warning, driver fatigue warning, and automatic lane following. Every year 70,000 people are killed in road accidents, 95% of which can be attributed to driver error. The potential outcomes of this project therefore significant. Many of the theoretical methods required for this project have been developed by our group. However, further theoretical refinements fo ....Autonomous Functions for Smart Cars. The aim of this project is to develop autonomous functions for smart cars, such as lane departure warning, driver fatigue warning, and automatic lane following. Every year 70,000 people are killed in road accidents, 95% of which can be attributed to driver error. The potential outcomes of this project therefore significant. Many of the theoretical methods required for this project have been developed by our group. However, further theoretical refinements followed by experimental verification is necessary. For smart cars to be accepted, the systems must be demonstrated to be reliable and to operate in a wide range of conditions.Read moreRead less
Affective sensing technology for the detection and monitoring of depression and melancholia. This project will develop reliable and affective sensing technology and evaluate it as an objective measure of depressive disorders; a leading cause of disability worldwide. Outcomes will significantly support and aid clinicians in their diagnosis and treatment, thus providing a major breakthrough with significant research, healthcare and commercial possibilities.
Location-Based Personalisation in Mobile Commerce (M-Commerce). M-commerce, though playing an important role in future competitiveness of Australia, suffers a low user demand. While location-based services have taken off in Europe, they are still at their infancy in Australia. In terms of IT access, Australia is ranked lower than many Asian countries. Our work gains an understanding of users' concerns and expectations of location-based services, which leads to better application designs and thus ....Location-Based Personalisation in Mobile Commerce (M-Commerce). M-commerce, though playing an important role in future competitiveness of Australia, suffers a low user demand. While location-based services have taken off in Europe, they are still at their infancy in Australia. In terms of IT access, Australia is ranked lower than many Asian countries. Our work gains an understanding of users' concerns and expectations of location-based services, which leads to better application designs and thus a wider adoption. An examination of users' attitude towards personalised content and concerns about data privacy provides insights to Australian legislation in relation to telemarketing and data-driven marketing. National benefits will stem from a balance between telemarketing efficiency and users' benefits.Read moreRead less
Automated internet warnings to prevent viewing of minor-adult sex images. Since the advent of the internet and digital cameras, the market for child exploitation material (CEM) has boomed. This project aims to explore how the visual appearance of warning messages influences internet users. It plans to conduct a randomised controlled experiment with naïve participants on a real-life website to test the effectiveness of messages designed to discourage viewers of legal ‘barely legal’ pornography. I ....Automated internet warnings to prevent viewing of minor-adult sex images. Since the advent of the internet and digital cameras, the market for child exploitation material (CEM) has boomed. This project aims to explore how the visual appearance of warning messages influences internet users. It plans to conduct a randomised controlled experiment with naïve participants on a real-life website to test the effectiveness of messages designed to discourage viewers of legal ‘barely legal’ pornography. It is anticipated that results will assist policing efforts by indicating whether warnings can be used to dissuade first-time CEM viewers and whether differences exist between harm or deterrent-focused messages.Read moreRead less
Reading facial expressions from real and virtual humans. This project aims to advance understanding of human emotional communication and improve human rapport with the virtual humans and avatars that are rapidly infiltrating our social world. Using two unique stimulus sets - naturalistic human expressions and highly realistic virtual faces - together with powerful genetic, experimental, and individual differences designs, the project expects to answer previously intractable questions in emotion ....Reading facial expressions from real and virtual humans. This project aims to advance understanding of human emotional communication and improve human rapport with the virtual humans and avatars that are rapidly infiltrating our social world. Using two unique stimulus sets - naturalistic human expressions and highly realistic virtual faces - together with powerful genetic, experimental, and individual differences designs, the project expects to answer previously intractable questions in emotion science, as well as deliver tangible outcomes, such as new psychological tests to better understand human social connection. This should provide significant benefits, by improving emotion communication and offering a new perspective on how artificial intelligence can best serve human social needs.
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Discovery Early Career Researcher Award - Grant ID: DE200101100
Funder
Australian Research Council
Funding Amount
$425,613.00
Summary
Towards Robotic Empathy: A human centred approach to future AI machines. The project aims to equip future robots with empathy by developing computational models which can leverage from verbal and non-verbal cues. With recent advances in artificial intelligence research, robots now have better cognitive and function skills, but they lack socio-emotional skills. Since these robots are expected to provide assistance to humans across different domains including rehabilitation, education and health c ....Towards Robotic Empathy: A human centred approach to future AI machines. The project aims to equip future robots with empathy by developing computational models which can leverage from verbal and non-verbal cues. With recent advances in artificial intelligence research, robots now have better cognitive and function skills, but they lack socio-emotional skills. Since these robots are expected to provide assistance to humans across different domains including rehabilitation, education and health care, empowering them with empathetic abilities is important for their success. The project will advance fundamental research in machine learning, affective computing and artificial intelligence to model human behavior, personality traits and emotions for an empathetic human-robot interaction.Read moreRead less
Improving the specificity of affective computing via multimodal analysis. This project aims to develop multimodal affective sensing techniques that can sense very subtle expressions in human moods and emotions. Much research in affective computing has investigated ways to improve the sensitivity of affect sensing approaches, resulting in more accurate estimates of affective states such as emotions or mood. What remains unsolved so far is the issue of specificity. This project will address this i ....Improving the specificity of affective computing via multimodal analysis. This project aims to develop multimodal affective sensing techniques that can sense very subtle expressions in human moods and emotions. Much research in affective computing has investigated ways to improve the sensitivity of affect sensing approaches, resulting in more accurate estimates of affective states such as emotions or mood. What remains unsolved so far is the issue of specificity. This project will address this issue through novel analyses of very subtle cues in facial and vocal expressions of affect embedded in a multimodal deep learning framework. Current approaches can successfully assist in binary classification tasks. This project will tackle the much more difficult problem of developing advanced affective sensing technology to simultaneously handle homogeneous and heterogeneous affect classes as well as continuous range estimates of affect intensity.Read moreRead less