Investigation Of Neuregulin Precessing By Beta-site APP Cleaving Enzyme And Gamma Secretase In Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$46,715.00
Summary
Schizophrenia (SCZ) is a complex psychiatric disorder that appears in male and female around adulthood. To date there is no clear pathological symptoms to identify SCZ individuals and place them in a specific group. Some proteins are genetically associated with this disease. I will investigate how some of these proteins disturb the function of the brain in human. My recent published data shows decrease of one of the proteins in the brain of SCZ group. My project may help develop novel and more s ....Schizophrenia (SCZ) is a complex psychiatric disorder that appears in male and female around adulthood. To date there is no clear pathological symptoms to identify SCZ individuals and place them in a specific group. Some proteins are genetically associated with this disease. I will investigate how some of these proteins disturb the function of the brain in human. My recent published data shows decrease of one of the proteins in the brain of SCZ group. My project may help develop novel and more selective therapies with less side-effects.Read moreRead less
Investigation Of The Functional Role Of Parkin And PArkin Co-Regulated Gene (PACRG) In Neurodegenerative Disease.
Funder
National Health and Medical Research Council
Funding Amount
$82,421.00
Summary
Parkinson’s disease (PD) is a chronic neurodegenerative disorder affecting greater than 1% of the population at 65 years of age. Current treatment regimes treat the motor-associated symptoms of disease - tremor and muscle rigidity. There is no cure, or effective treatment to reverse or halt disease progression. Understanding the role of dysregulated proteins in the progression of PD will identify new targets for treatment of the motor and cognitive deficits observed in PD-affected individuals.