Micro-disperse sintered nano-diamonds: a new class of versatile adsorbent for high performance liquid chromatography. Nano-diamond is currently recognised amongst researchers as a highly significant material for the development of new technologies in analytical science, diagnostics and nano-technology. Here, sintered nano-diamond, with its many unique properties, will provide a new generation of stationary phases for use in high performance liquid chromatography.
High performance chromatography based on nanostructured monolithic polymers. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pharmaceutical analysis and drug discovery; environmental, clinical, and ....High performance chromatography based on nanostructured monolithic polymers. The proposed project will generate highly significant, fundamental advances in separation science by developing new stationary phases and separation technologies suitable for the analysis of very complex samples which cannot be addressed by current methods. These technologies will be applied in a wide range of areas of national importance including pharmaceutical analysis and drug discovery; environmental, clinical, and forensic analysis; energy generation and foods. The project will also lead to very significant new intellectual property having extremely high commercial potential worldwide, and thereby generates the promise of considerable direct financial returns to Australia.Read moreRead less
Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug develo ....Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug development, and also for performing clinical diagnostics in a rural area. This will significantly impact on the quality of life of the Nation as a whole, not only due to expedient diagnosis and treatment which has obvious health benefits, but also in the considerable financial benefits that result from early and efficient treatment. Read moreRead less
Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the var ....Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the various Federal and State police and forensic agencies, and the customs service, etc, highlights the importance of this project to the nation. Finally, a PhD student and a research assistant will be involved with the project and will gain specialised skills positioning them to make strong contributions to Australia's counter-terrorism measures.Read moreRead less
Automated Sensors for a ‘wetland in a box’. Globally, and particularly in Australia, water supply and water pollution is one of the most critical constraints to our health and growth. This project seeks to validate a new portable remediation system suitable for deployment at regional locations through the integration and development of advanced sensors. We aim to develop the world’s first completely integrated platform for monitoring both water chemistry and microbiology to provide near-real-tim ....Automated Sensors for a ‘wetland in a box’. Globally, and particularly in Australia, water supply and water pollution is one of the most critical constraints to our health and growth. This project seeks to validate a new portable remediation system suitable for deployment at regional locations through the integration and development of advanced sensors. We aim to develop the world’s first completely integrated platform for monitoring both water chemistry and microbiology to provide near-real-time information regarding the quality of the remediated water. We expect this to improve the availability of regional water resources by providing a low-cost remediation solution with integrated monitoring to provide assurances of meeting the Australian Guidelines for Water Recycling (2006).Read moreRead less
Green sample preparation technologies for analytical chemistry. This project opens new directions for the sample preparation of small molecules, nanoparticles and bacterial cells prior to analysis and will reduce pollution from chemical laboratories. The proposed 'green' analytical chemistry techniques will strengthen the position of Australia as a world-leader in separation science.
Miniaturised electrophoretic systems for distributed environmental sensing. This project aims to develop new low-cost sensors to quantify a range of water nutrients for continuous automated water monitoring. The project aims to design a microfluidic cartridge to obtain a particulate-free sample for analysis by the rapid separation of inorganic anions and cations. The cartridge is intended to be operated in a portable low cost, low weight, low power instrument. The deployment of multiple units ai ....Miniaturised electrophoretic systems for distributed environmental sensing. This project aims to develop new low-cost sensors to quantify a range of water nutrients for continuous automated water monitoring. The project aims to design a microfluidic cartridge to obtain a particulate-free sample for analysis by the rapid separation of inorganic anions and cations. The cartridge is intended to be operated in a portable low cost, low weight, low power instrument. The deployment of multiple units aims to provide a continuous data stream describing the changes in nutrient profiles within various waters, to feed into environmental models and inform best practice for agriculture and aquaculture industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100043
Funder
Australian Research Council
Funding Amount
$389,000.00
Summary
Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies. This project aims to undertake fast probe-free biochemical/chemical imaging of heterogeneity within cells and materials surfaces with new infrared and Raman imaging. It will generate new fundamental knowledge on: cell heterogeneity and dynamic processes; technologies for optimising cell printing; understanding toxicity of microplastics; and protocols for measuring materials of technological relevance. Expected outcomes inc ....Rapid Molecular (Bio)material Imaging by Infrared and Raman Microscopies. This project aims to undertake fast probe-free biochemical/chemical imaging of heterogeneity within cells and materials surfaces with new infrared and Raman imaging. It will generate new fundamental knowledge on: cell heterogeneity and dynamic processes; technologies for optimising cell printing; understanding toxicity of microplastics; and protocols for measuring materials of technological relevance. Expected outcomes include: interdisciplinary collaborations in new protocols for in-vitro drug development; cell printing technologies; environmental impacts of microplastics; and materials design. Expected benefits include innovative approaches to early stage drug design; improved environmental controls and advances in innovative materials.Read moreRead less
Portable and field-deployable analytical platforms for water monitoring. This project sets out to tackle one of the costliest and most challenging environmental problems, namely, nutrient pollution in water systems. At present, nutrient pollutant monitoring is predominantly carried out using an antiquated manual approach with numerous shortcomings, inadequate to achieve truly effective water quality management. The in-situ analyser developed and deployed within this project will provide continuo ....Portable and field-deployable analytical platforms for water monitoring. This project sets out to tackle one of the costliest and most challenging environmental problems, namely, nutrient pollution in water systems. At present, nutrient pollutant monitoring is predominantly carried out using an antiquated manual approach with numerous shortcomings, inadequate to achieve truly effective water quality management. The in-situ analyser developed and deployed within this project will provide continuous real-time observations and will allow users to remotely monitor water quality; alerting them to pollutant levels, enabling immediate action to be taken to prevent environmental damage. The system is low-cost, facilitating mass adoption, yet delivers an analytical performance comparable to leading laboratory analysers. Read moreRead less